arXiv Machine Learning

Pre-AF 13: An Interpretable Atrial Fibrillation Risk Score Mined from Discharge Reports

arXiv:2606. 10725v1 Announce Type: new Abstract: Background.

arXiv AI
Aug 7

Trajectory-guided discharge stratification for heart failure using short-context electronic health record sequence modeling

arXiv:2511. 16839v4 Announce Type: replace-cross Abstract: Purpose: Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging.

By Falk Dippel, Yinan Yu, Annika Rosengren, Martin Lindgren, Christina E. Lundberg, Erik Aerts, Martin Adiels, Helen Sj\"oland
arXiv AI
Aug 5

FOUND-AF: Benchmarking ECG Foundation Models for Atrial Fibrillation Detection

arXiv:2608. 03597v1 Announce Type: new Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risks of stroke, heart failure, and mortality.

By Amirhossein Taleshinosrati, Yangyang Wang, Atitaya Phoemsuk, Vahid Abolghasemi, Naser Hossein Motlagh, Sadasivan Puthusserypady, Daniel Teichmann, Abdolrahman Peimankar
arXiv Machine Learning
Jun 2

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Machine Learning
Jul 20

CardioMeta: Calibrated Multi-Task Prediction of Diabetes, Hypertension, and Cardiovascular Disease Across Population and EHR Data

arXiv:2607. 15721v1 Announce Type: new Abstract: Cardiometabolic diseases remain among the most persistent drivers of preventable morbidity because diabetes, hypertension, and cardiovascular disease frequently co-occur and share metabolic, vascular, demographic, and behavioral determinants.

By S M Asif Hossain, Ruksat Khan Shayoni, M. F. Mridha, Jungpil Shin
arXiv AI
Aug 24

Fine-tuning an ECG Foundation Model to Predict Coronary CT Angiography Outcomes

A multicenter study developed an AI-enabled electrocardiography (AI-ECG) model that predicts vessel-specific hemodynamically significant stenosis using coronary computed tomographic angiography (CCTA) as the reference. The model demonstrated strong discrimination in internal and external cohorts, including normal ECGs, and produced low-, intermediate-, and high-risk strata that correlated with stenosis severity and major adverse cardiovascular events. Calibration, decision curve analyses, and integration with guideline-based pre-test probability showed clinical utility, while waveform and attribution analyses revealed physiologically meaningful ECG features linked to high-risk predictions.

By Yujie Xiao, Qinghao Zhao, Gongzheng Tang, Hao Zhang, Zhuoran Kan, Deyun Zhang, Jun Li, Guangkun Nie, Xiaocheng Fang, Haoyu Wang, Shun Huang, Tong Liu, Jian Liu, Kangyin Chen, Shenda Hong
arXiv Machine Learning
4d ago

Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

arXiv:2601.00175v3 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Computation and Language
Sep 11

Target leakage, not model class, explains reported accuracy in survey-based cardiovascular screening: a leakage-tiered audit of glass-box and tabular foundation models

The study audited ten different classifiers—including linear, tree‑ensemble, neural, glass‑box, and tabular foundation models—on national health survey data to predict myocardial infarction. By systematically removing features that could cause target leakage, the authors found that all models’ AUROC scores collapsed into a narrow band, indicating that reported high accuracy in prior work was largely due to leakage rather than model sophistication. The glass‑box explainable boosting machine performed comparably to other models while being much faster, and the authors demonstrated that fairness, calibration, and uncertainty can be audited and repaired without sacrificing performance.

By Raad Bin Tareaf, Murad Al-Rajab, Samia Loucif, Samer Ellaham, Cedric Schmitz
arXiv Machine Learning
Sep 18

Interpretable and Calibrated Classification of Clinical Data Using Supervised Feature Binarization

The paper introduces a statistically grounded framework for interpretable, rule-based clinical classification using Bernoulli Naïve Bayes (BNB). It employs supervised chi‑square‑guided binarization to convert continuous medical variables into binary indicators, enabling BNB to handle continuous data while maintaining transparency. On three benchmark datasets—Pima Indians Diabetes, Wisconsin Breast Cancer, and Heart Failure Prediction—the method achieved AUCs of 0.800, 0.984, and 0.919, respectively, and demonstrated reliable probability calibration through cross‑validated analysis and post‑hoc beta calibration.

By Antony Garcia, Adrian Noriega, Gabrielle Britton, Xinming Huang