The paper introduces a statistically grounded framework for interpretable, rule-based clinical classification using Bernoulli Naïve Bayes (BNB). It employs supervised chi‑square‑guided binarization to convert continuous medical variables into binary indicators, enabling BNB to handle continuous data while maintaining transparency. On three benchmark datasets—Pima Indians Diabetes, Wisconsin Breast Cancer, and Heart Failure Prediction—the method achieved AUCs of 0.800, 0.984, and 0.919, respectively, and demonstrated reliable probability calibration through cross‑validated analysis and post‑hoc beta calibration.
arXiv:2607. 15394v1 Announce Type: new Abstract: Black-box models limit the adoption of artificial intelligence in medicine due to their lack of interpretability and reproducibility.
arXiv:2608. 04046v1 Announce Type: cross Abstract: Survival analysis is an established framework for analyzing time-to-event data, yet many clinical machine learning studies still binarize the outcome before model training.
arXiv:2601. 22324v3 Announce Type: replace Abstract: Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules.
arXiv:2606. 16337v1 Announce Type: new Abstract: Predictive modeling for clinical tabular data is central to clinical decision support and therefore requires not only strong predictive performance but also transparent decision logic.
The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.
The paper introduces a four-step pipeline that mines decision rules in the latent space of an FT-Transformer and then translates those rules back into measurable clinical features. By treating embedding dimensions that separate patient groups as latent biomarkers, small decision trees are used to extract rules, which are then mapped to raw features using gradient-input saliency and CLS attention attribution. Across six public clinical datasets, the translated rules generally outperformed raw-feature rules, achieving significant AUROC gains, though some high-performing latent rules could not be fully captured by simple raw-feature conditions.
arXiv:2605. 29058v2 Announce Type: replace Abstract: Bayesian Networks (BNs) are of interest from an explainable AI viewpoint, offering transparent probabilistic models for decision support.
arXiv:2607. 09165v1 Announce Type: cross Abstract: Achieving early and timely diagnosis and treatment for disease is a major challenge.
arXiv:2609.13192v1 Announce Type: new Abstract: This study compares traditional machine learning models and Large Language Model (LLM)-generated rule-based systems for heart disease prediction using...
arXiv:2603. 02221v2 Announce Type: replace-cross Abstract: In clinical tabular prediction, classical machine learning models with feature engineering often outperform neural methods.
arXiv:2608.29419v1 Announce Type: cross Abstract: Deep learning architectures are increasingly proposed for patient trajectory modeling in electronic health records (EHRs), yet their advantage over s...
arXiv:2608. 05203v1 Announce Type: new Abstract: Machine learning models achieve strong predictive accuracy for 90-day outcome prediction in acute ischaemic stroke, yet clinical adoption is limited by the misalignment of model explanations with clinicians' reasoning.