arXiv:2607. 15721v1 Announce Type: new Abstract: Cardiometabolic diseases remain among the most persistent drivers of preventable morbidity because diabetes, hypertension, and cardiovascular disease frequently co-occur and share metabolic, vascular, demographic, and behavioral determinants.
arXiv:2505. 16941v4 Announce Type: replace-cross Abstract: Foundation models (FMs) promise to address core limitations of traditional supervised machine learning: (i) reliance on large amounts of labeled data, (ii) task specificity, and (iii) poor transportability.
The paper introduces a framework that distinguishes two causes of saturation in clinical prediction: a learner gap, where the model fails to use available information, and a measurement‑channel ceiling, where the recorded variables limit performance. It provides theoretical characterizations, finite‑sample diagnostics, and empirical audits across three large cohorts, showing that well‑tuned models approach the frontier while deficient learners leave large gaps. A PRISMA‑guided synthesis across 104 tasks reveals consistent channel‑level patterns, suggesting that improving the learner or the measurement channel can audit and potentially lift performance.
The paper introduces CALIBRA, a calibration-first multimodal temporal learning framework designed for transferable asthma‑risk forecasting across varying patient cohorts and sensor ecosystems. It processes multiple data streams—environmental, pulmonary, symptom, medication, wearable, and context—using dedicated recurrent encoders, a reliability‑conditioned gate, and gradient‑reversal training to mitigate cohort bias. CALIBRA employs a shrinkage‑based hierarchical logistic layer for probability calibration and split conformal prediction for abstention‑capable prediction sets, achieving competitive performance on a semi‑synthetic three‑cohort benchmark with controlled distribution shift.
arXiv:2511. 16839v4 Announce Type: replace-cross Abstract: Purpose: Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging.
arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.
arXiv:2607. 15394v1 Announce Type: new Abstract: Black-box models limit the adoption of artificial intelligence in medicine due to their lack of interpretability and reproducibility.
arXiv:2608.29301v1 Announce Type: new Abstract: Predicting future organ dysfunction in Intensive Care Unit (ICU) patients is critical for early clinical intervention, yet existing machine learning ap...
The paper introduces Scaling Electronic Health Record Foundation Models for Population Health Management, a large‑scale model trained on billions of medical events from over 5 million patients in Taiwan and the United States. By aligning ICD codes across different health systems, the model achieves strong scaling and generalization across 11 chronic disease prediction tasks, outperforming tree‑based, general, and biomedical language models with high sensitivity at 99% specificity. It also demonstrates superior few‑shot performance on the EHRShot benchmark and shows that cross‑system alignment provides a stronger pretraining signal than single‑site duplication in data‑limited scenarios.
arXiv:2607. 23412v1 Announce Type: new Abstract: Electrocardiograms (ECGs) are widely used for cardiovascular risk prediction, yet models often fail to transfer across hospitals because of protocol, population, and measurement differences.
arXiv:2606. 30702v1 Announce Type: cross Abstract: Structured tabular data dominates clinical medicine, yet existing benchmarks fail to reflect real-world properties like complex survey sampling, demographic oversampling, and subgroup fairness.
arXiv:2606. 10725v1 Announce Type: new Abstract: Background.
arXiv:2607. 11656v1 Announce Type: cross Abstract: Accurate diagnostic classification and disease-severity prediction for Alzheimer's disease are hampered by the incompleteness and heterogeneity of real-world clinical data.