arXiv AI

The Ceiling Is in the Channel: Auditing Learner Gaps and Measurement Frontiers in Clinical Prediction

The paper introduces a framework that distinguishes two causes of saturation in clinical prediction: a learner gap, where the model fails to use available information, and a measurement‑channel ceiling, where the recorded variables limit performance. It provides theoretical characterizations, finite‑sample diagnostics, and empirical audits across three large cohorts, showing that well‑tuned models approach the frontier while deficient learners leave large gaps. A PRISMA‑guided synthesis across 104 tasks reveals consistent channel‑level patterns, suggesting that improving the learner or the measurement channel can audit and potentially lift performance.

arXiv AI
Aug 11

FoMoH: A clinically meaningful foundation model evaluation for structured electronic health records

arXiv:2505. 16941v4 Announce Type: replace-cross Abstract: Foundation models (FMs) promise to address core limitations of traditional supervised machine learning: (i) reliance on large amounts of labeled data, (ii) task specificity, and (iii) poor transportability.

By Vincent Jeanselme, Zilin Jing, Aparajita Kashyap, Chao Pang, Florent Pollet, Young Sang Choi, Xinzhuo Jiang, Yuta Kobayashi, Yanwei Li, Sara Matijevic, Karthik Natarajan, Shalmali Joshi
arXiv Machine Learning
Jul 14

Imputation-free transformer learning enables robust Alzheimer's disease prediction and calibrated uncertainty quantification across heterogeneous clinical cohorts

arXiv:2607. 11656v1 Announce Type: cross Abstract: Accurate diagnostic classification and disease-severity prediction for Alzheimer's disease are hampered by the incompleteness and heterogeneity of real-world clinical data.

By Christelle Schneuwly Diaz, Narmina Baghirova, Duy-Thanh Vu, Duy-Cat Can, Gilles Allali, Philippe Ryvlin, Oliver Y. Ch\'en
arXiv Machine Learning
Jul 20

CardioMeta: Calibrated Multi-Task Prediction of Diabetes, Hypertension, and Cardiovascular Disease Across Population and EHR Data

arXiv:2607. 15721v1 Announce Type: new Abstract: Cardiometabolic diseases remain among the most persistent drivers of preventable morbidity because diabetes, hypertension, and cardiovascular disease frequently co-occur and share metabolic, vascular, demographic, and behavioral determinants.

By S M Asif Hossain, Ruksat Khan Shayoni, M. F. Mridha, Jungpil Shin
arXiv Machine Learning
Jul 21

Differentiable latent structure discovery for interpretable forecasting in clinical time series

arXiv:2604. 27967v2 Announce Type: replace Abstract: Background: We introduce StructGP, a continuous-time multi-task Gaussian process that couples process convolutions with differentiable structure learning to uncover a sparse, ordered directed acyclic graph (DAG) of inter-variable dependencies while preserving principled uncertainty.

By Ivan Lerner, Jean Feydy, Alexandre Kalimouttou, Anita Burgun, Francis Bach
arXiv AI
Aug 20

FairGlucose: A CGM Fairness Benchmark Reveals Subgroup Disparities Hidden in Population-Level Validation

FairGlucose is a 300‑patient CGM cohort balanced across 12 demographic strata, providing 132,480 forecasting samples and 3,945 behavioral events. Benchmarking 33 models on 2‑hour glucose forecasting revealed that population‑level validation masks significant subgroup disparities, with error ratios ranging from 0.8 to 1.4 and T1D patients experiencing 6 mg/dL higher error than T2D. The study shows that these gaps persist across all models, align with clinically hard cases, and vary with input‑length sensitivity, underscoring the need for subgroup‑disaggregated reporting in digital health AI.

By Junjie Luo, Xuzhe Zhi, Rui Han, Abhimanyu Kumbara, Anand K. Iyer, Mansur E. Shomali, Ritu Agarwal, Guodong Gordon Gao
arXiv AI
Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing
arXiv Machine Learning
Jul 30

CalTwin: Towards Calibrated, Shift-Robust Medical World Models via Fisher-Information Regularisation

arXiv:2607. 26752v1 Announce Type: new Abstract: Medical world models aim to learn a latent state of patient or organ physiology and a transition function that forecasts how that state evolves under interventions, supporting downstream tasks from imaging-based diagnosis to digital-twin treatment planning.

By Behraj Khan, Shabir Ahmad, Syed Ahmad Chan Bukhari, Tahir Qasim Syed
arXiv Computer Vision
Aug 27

Reliability analysis for BraTS-GoAT segmentation: a controlled robustness study of deep-ensemble uncertainty

The study evaluates the reliability of deep‑ensemble uncertainty for brain tumour segmentation on the BraTS‑GoAT dataset. A 5‑fold cross‑validated nnU‑Net baseline and a 3‑seed deep ensemble were compared for calibration and error detection; the ensemble showed modest gains in calibration on in‑distribution data but the single model’s confidence remained flat while accuracy degraded under synthetic corruptions. Disagreement among ensemble members rose sharply with corruption severity, proving to be a more sensitive indicator of acquisition shift than single‑model confidence.

By Riya Deepak Shet, Chenxi Liang, Le Zhang