arXiv:2607. 20453v1 Announce Type: cross Abstract: Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models.
By Jessica Sena, Shesadree Priyadarshani, Miguel Contreras, Bharat Gandhi, Scott Siegel, Subhash Nerella, Parisa Rashidi
arXiv:2607. 28788v1 Announce Type: new Abstract: Clinical diagnosis at hospital admission must be made rapidly from limited, incomplete evidence.
By Jiahui Li, Ruili Fang, Zishuai Liu, Yutong Guo, Nan Yang, Wenzhan Song, Jin Lu, Fei Dou
arXiv:2601. 14590v3 Announce Type: replace Abstract: Counterfactual explanations (CFEs) provide human-centric interpretability by identifying the minimal, actionable changes required to alter a machine learning model's prediction.
By Shovito Barua Soumma, Asiful Arefeen, Stephanie M. Carpenter, Melanie Hingle, Hassan Ghasemzadeh
arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.
By Raghu Vamshi Hemadri, Geetha Krishna Guruju, Kristi Topollai, Anna Ewa Choromanska
arXiv:2505. 16941v4 Announce Type: replace-cross Abstract: Foundation models (FMs) promise to address core limitations of traditional supervised machine learning: (i) reliance on large amounts of labeled data, (ii) task specificity, and (iii) poor transportability.
By Vincent Jeanselme, Zilin Jing, Aparajita Kashyap, Chao Pang, Florent Pollet, Young Sang Choi, Xinzhuo Jiang, Yuta Kobayashi, Yanwei Li, Sara Matijevic, Karthik Natarajan, Shalmali Joshi
arXiv:2606. 18933v1 Announce Type: new Abstract: Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision.
By Binyamin Perets, Natalie Mendelson, Shiran Vainberg, Yehuda Chowers, Shai Shen-Orr, Shie Mannor
arXiv:2606. 12006v1 Announce Type: cross Abstract: Predicting time-to-event outcomes such as mortality is a fundamental task in clinical decision-making, commonly addressed through survival analysis.
By Minh-Khoi Pham, Luca Cotugno, Alina Sirbu, Tai Tan Mai, Martin Crane, Marija Bezbradica
arXiv:2608. 14792v1 Announce Type: cross Abstract: Objectives: To determine whether zero-shot prompting of a large language model (LLM) is sufficient to detect shared decision-making (SDM) behaviors in real clinical encounters, and whether supervised learning adds value under patient-grouped, nested evaluation.
By Bernardo Modenesi, Jody Lin, Kimberly Kaphingst, Angela Zhu, Maya Wheeler, Peilu Zhang, Angela Fagerlin
arXiv:2606. 19183v1 Announce Type: cross Abstract: Large language models (LLMs) can make clinical decision support more accessible by interpreting free-text documentation, but their direct use as diagnostic engines is limited by sensitivity to prompts, information order, and plausible but incorrect outputs.
By Soheyl Bateni, Maryam Abdolali
arXiv:2602. 19502v2 Announce Type: replace Abstract: Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide.
By Lalitha Pranathi Pulavarthy, Raajitha Muthyala, Aravind V Kuruvikkattil, Zhenan Yin, Rashmita Kudamala, Saptarshi Purkayastha
arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.
By Lin Lawrence Guo, Adam Paul Yan, Emily Vettese, Lillian Sung
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi