arXiv:2506.15626v3 Announce Type: replace-cross Abstract: $\textbf{Objective:}$ Brain-predicted age difference (BrainAGE) is a neuroimaging biomarker reflecting brain health. However, training robust...
The study investigates how image‑domain Poisson perturbations affect the classification of ischemic core/penumbra in non‑contrast CT slices. Using a CPAISD cohort, the authors compared direct ResNet‑18 classification with a denoising‑then‑classifying pipeline and found that denoising generally reduced performance. A prospective experiment with joint denoising‑classification models showed no statistically significant advantage over direct noisy classification, indicating limited robustness to Poisson noise.
arXiv:2609.37387v1 Announce Type: cross Abstract: Enlarged perivascular spaces (PVS) visible in brain magnetic resonance imaging (MRI) are increasingly thought to be linked to poor brain health. PVS...
MIRTO is an evaluation protocol for unsupervised anomaly segmentation in brain MRI that explicitly documents key methodological choices—such as registration alignment, threshold setting, and false‑positive budgeting—and measures their impact. It applies a registration check, uses validation data for thresholding, reports realized false‑positive volumes, and repeats each comparison across 15,552 evaluation pipelines with bootstrap intervals. In a study on four UAD methods and 312 BraTS 2020 subjects, MIRTO revealed that an axis‑order mismatch dramatically lowered a diffusion model’s voxel AUROC, and that many performance differences were driven by lesion definition and threshold transfer rather than model quality.
arXiv:2608. 06429v1 Announce Type: cross Abstract: Interpretability methods for large language models (LLMs) describe internal state but do not directly test whether that state is causally sufficient to produce the observed behavior.
arXiv:2609.15888v1 Announce Type: cross Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
This study presents a domain-aware deep learning framework based on nnU-Net for segmenting ischemic stroke lesions on non‑contrast CT scans and quantifying net water uptake (NWU). Trained on data from Hamburg and the Acute Ischemic Stroke Dataset, the model was fine‑tuned on small target‑domain subsets from Boston and ISLES, achieving median Dice scores of 0.68 and 0.56 for lesions ≥30 mL, and an NWU mean absolute error of 1.37 percentage points on the Boston cohort. The results demonstrate that target‑domain adaptation can enable accurate NCCT‑only infarct segmentation and low‑error NWU estimation across heterogeneous multicenter datasets.
arXiv:2603.28387v3 Announce Type: replace-cross Abstract: Trustworthy clinical AI must use real evidence and avoid relying on surface-level artifacts. We evaluate 12 open-weight vision-language model...
The study evaluated a pragmatic deep‑learning approach for segmenting acute ischemic stroke lesions on diffusion‑weighted MRI. Using a self‑configured nnU‑Net trained on 1,744 cases and tested on 436, the baseline model achieved a median Dice similarity coefficient of 0.84, outperforming the DeepISLES ensemble, especially for smaller infarcts. The approach required minimal preprocessing and fast inference, suggesting it could streamline clinical stroke imaging workflows.
arXiv:2609.36837v1 Announce Type: cross Abstract: Generative super-resolution models can turn portable 64 mT MRI into images that look like 3T scans, and the field evaluates them with PSNR, SSIM, and...
The paper introduces NeuroFusion, an assistive brain‑MRI report generator that surfaces latent tumor signals from a frozen Mistral‑7B backbone. By adding discriminative field‑classifier heads over per‑lesion features, NeuroFusion restores accurate diagnoses (meningioma 0.92, metastasis 0.75) and improves prose quality while reducing latency 5–6×. A controlled negative result shows that overriding the decoder with a learned diagnosis pin harms performance, and grammar‑constrained decoding yields high schema‑validity (92.3%).
The paper examines dataset contamination in public brain‑tumor MRI classification benchmarks, introducing a three‑layer framework—duplicate, patient, and source‑label leakage—to evaluate integrity. Audits of the three most used corpora reveal severe leakage: up to 28.8% of test images duplicate training images, 22.3% are byte‑identical, and 95.5% share patients with training data. Even after removing all leaked images, model accuracy remains unchanged, indicating that benchmark integrity cannot be inferred from stable leaderboard scores alone.