This study presents a domain-aware deep learning framework based on nnU-Net for segmenting ischemic stroke lesions on non‑contrast CT scans and quantifying net water uptake (NWU). Trained on data from Hamburg and the Acute Ischemic Stroke Dataset, the model was fine‑tuned on small target‑domain subsets from Boston and ISLES, achieving median Dice scores of 0.68 and 0.56 for lesions ≥30 mL, and an NWU mean absolute error of 1.37 percentage points on the Boston cohort. The results demonstrate that target‑domain adaptation can enable accurate NCCT‑only infarct segmentation and low‑error NWU estimation across heterogeneous multicenter datasets.
By Linus Britt, Maximilian Nielsen, Susan Klapproth, Andre Kemmling, Michael H. Lev, Gabriel Broocks, Rene Werner, Thilo Sentker
The paper introduces a bi‑temporal framework that links admission computed tomography perfusion (CTP) data with follow‑up diffusion‑weighted MRI (DWI) outcomes in acute ischemic stroke. By extracting statistical, radiomic, and deep‑learning features from CTP and classifying tissue into six outcome‑aware regions, the authors demonstrate that CTP signatures can distinguish salvaged versus infarcted penumbra and identify non‑hypoperfused tissue that later infarcts. Cross‑dataset validation on the ISLES'24 dataset confirms consistent feature‑space separations, suggesting that admission CTP contains richer outcome information than traditional core‑penumbra delineation.
By Md Sazidur Rahman, Kjersti Engan, Kathinka D{\ae}hli Kurz, Mahdieh Khanmohammadi
arXiv:2607. 03568v1 Announce Type: cross Abstract: Objective: Accurate identification of acute ischemic infarcts on diffusion-weighted magnetic resonance imaging (DWI) is a critical prerequisite for reliable lesion quantification and effective clinical decision support in the management of cerebrovascular events.
By Hasan Ulutas, Muhammet Emin Sahin, Mustafa Fatih Erkoc, Esra Yuce, Turker Tuncer, Sengul Dogan, Serkan Kiranyaz
arXiv:2601. 20503v2 Announce Type: replace-cross Abstract: White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are key imaging biomarkers of cerebral small vessel disease (SVD) detectable on magnetic resonance imaging (MRI).
By Jesse Phitidis, Alison Q. Smithard, William N. Whiteley, Joanna M. Wardlaw, Miguel O. Bernabeu, Maria Vald\'es Hern\'andez
arXiv:2608. 19769v1 Announce Type: cross Abstract: Fast and accurate segmentation of Acute Ischemic Stroke (AIS) lesions is essential for stroke prognosis and treatment planning.
By Maunil Shah, Vaanathi Sundaresan
arXiv:2609.15888v1 Announce Type: cross
Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
By Paul-Gabriel Nicolae, Irina Georgiana Mocanu
arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.
By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
arXiv:1907.09194v3 Announce Type: replace-cross
Abstract: Segmentation of subcortical brain structures is fundamental to computer-aided diagnosis and treatment in neurology and related clinical field...
By Binbin Yang, Weiwei Zhang
arXiv:2610.00279v1 Announce Type: new
Abstract: The segmentation of anatomical structures in medical images and particularly in MRI scans, is essential for clinical diagnosis and monitoring disease p...
By Eirini Cholopoulou, Dimitrios E. Diamantis, Dimitris K. Iakovidis
arXiv:2606. 01293v1 Announce Type: cross Abstract: Accurate segmentation of fetal brain tissues in Magnetic Resonance Imaging (MRI) is critical for early diagnosis of congenital abnormalities and improving prenatal care.
By Ashiqur Rahman, Muhammad E. H. Chowdhury, Md. Abu Sayed, Md. Sharjis Ibne Wadud, Abu Naser Md. Arafat, Mehedi Hasan Prince
arXiv:2606. 29106v1 Announce Type: cross Abstract: Neurological disorders involve diverse pathologies of the brain and nervous system, making early and accurate detection essential.
By Ali Fatahi, Hoda Zamani, Mohammad H. Nadimi-Shahraki
arXiv:2608.23745v1 Announce Type: cross
Abstract: Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis, treatment planning, surgical guidance, and diseas...
By Mohammad Mahdi Danesh Pajouh, Sara Saeedi