This study presents a domain-aware deep learning framework based on nnU-Net for segmenting ischemic stroke lesions on non‑contrast CT scans and quantifying net water uptake (NWU). Trained on data from Hamburg and the Acute Ischemic Stroke Dataset, the model was fine‑tuned on small target‑domain subsets from Boston and ISLES, achieving median Dice scores of 0.68 and 0.56 for lesions ≥30 mL, and an NWU mean absolute error of 1.37 percentage points on the Boston cohort. The results demonstrate that target‑domain adaptation can enable accurate NCCT‑only infarct segmentation and low‑error NWU estimation across heterogeneous multicenter datasets.
By Linus Britt, Maximilian Nielsen, Susan Klapproth, Andre Kemmling, Michael H. Lev, Gabriel Broocks, Rene Werner, Thilo Sentker
The paper introduces a bi‑temporal framework that links admission computed tomography perfusion (CTP) data with follow‑up diffusion‑weighted MRI (DWI) outcomes in acute ischemic stroke. By extracting statistical, radiomic, and deep‑learning features from CTP and classifying tissue into six outcome‑aware regions, the authors demonstrate that CTP signatures can distinguish salvaged versus infarcted penumbra and identify non‑hypoperfused tissue that later infarcts. Cross‑dataset validation on the ISLES'24 dataset confirms consistent feature‑space separations, suggesting that admission CTP contains richer outcome information than traditional core‑penumbra delineation.
By Md Sazidur Rahman, Kjersti Engan, Kathinka D{\ae}hli Kurz, Mahdieh Khanmohammadi
arXiv:2607. 03568v1 Announce Type: cross Abstract: Objective: Accurate identification of acute ischemic infarcts on diffusion-weighted magnetic resonance imaging (DWI) is a critical prerequisite for reliable lesion quantification and effective clinical decision support in the management of cerebrovascular events.
By Hasan Ulutas, Muhammet Emin Sahin, Mustafa Fatih Erkoc, Esra Yuce, Turker Tuncer, Sengul Dogan, Serkan Kiranyaz
arXiv:2601. 20503v2 Announce Type: replace-cross Abstract: White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are key imaging biomarkers of cerebral small vessel disease (SVD) detectable on magnetic resonance imaging (MRI).
By Jesse Phitidis, Alison Q. Smithard, William N. Whiteley, Joanna M. Wardlaw, Miguel O. Bernabeu, Maria Vald\'es Hern\'andez
arXiv:2608. 19769v1 Announce Type: cross Abstract: Fast and accurate segmentation of Acute Ischemic Stroke (AIS) lesions is essential for stroke prognosis and treatment planning.
By Maunil Shah, Vaanathi Sundaresan
arXiv:2609.15888v1 Announce Type: cross
Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
By Paul-Gabriel Nicolae, Irina Georgiana Mocanu