The paper presents a pragmatic segmentation pipeline for brain metastases in the BraTS 2026 Task 1, using a 5‑fold nnU-Net ResEnc‑L ensemble trained for 1,000 epochs on 1,296 four‑modality cases. A rule‑based post‑processing cascade tuned for the lesion‑wise Dice similarity coefficient (LW‑DSC) improves performance, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 on enhancing tumour, tumour core, whole tumour, and resection cavity, respectively. The authors audit each post‑processing stage with a five‑fold out‑of‑fold analysis, confirm two stages as robust, and provide a mechanistic analysis of LW‑DSC, along with thirteen negative results that challenge common intuitions.
The paper presents a segmentation pipeline for brain metastases in both pre‑ and post‑treatment cases using a 5‑fold nnU‑Net ResEnc‑L ensemble trained on 1,296 four‑modality cases. A rule‑based post‑processing cascade improves the lesion‑wise Dice similarity coefficient (LW‑DSC) for enhancing tumour, tumour core, whole tumour, and resection cavity sub‑regions, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 respectively on the official validation leaderboard. The authors conduct a five‑fold out‑of‑fold analysis to validate the robustness of each post‑processing stage, provide a mechanistic explanation of LW‑DSC behaviour, and report thirteen negative results that challenge common intuitions, with all code released under Apache‑2.0.
By Haobin Liu, Xin Wang
arXiv:2610.08660v1 Announce Type: new
Abstract: Background: Biomedical AI can generate plausible explanations without reliably verifying whether each statement is supported by patient-specific eviden...
By Mariya Miteva, Maria Nisheva-Pavlova
arXiv:2607. 16317v1 Announce Type: cross Abstract: Deep networks now subtype brain tumors on MRI about as well as specialist readers, yet accuracy is not what keeps them out of the clinic.
By Medhansh Sharma
arXiv:2609.16597v1 Announce Type: cross
Abstract: Background Non-invasive presurgical diagnosis of brain tumor types from Magnetic Resonance Imaging (MRI) is essential but challenging due to overlapp...
By Yinong Wang (Joyce), Jianwen Chen (Joyce), Zhou Chen (Joyce), Shuwen Kuang (Joyce), Haoning Jiang (Joyce), Yanzhao Shi (Joyce), Huichun Yuan (Joyce), Yan-ran (Joyce), Wang, Bing Wang, Lei Wu, Bin Tang, Li Meng, Baihua Luo, Bin Zhou, Wei Ding, Weiming Zhong, Wei Hou, Yuanbing Chen, Zhiping Wan, Wei Wang, Zhenkun Xiao, Wenwu Wan, Allen He, Yuyin Zhou, Longbo Zhang, Feifei Wang, Zhixiong Liu, Michael Iv, Xuan Gong, Liangqiong Qu
arXiv:2609.24769v1 Announce Type: new
Abstract: Brain metastases are the most common intracranial malignancy, occurring in roughly 30% of patients with primary solid tumors and carrying a median surv...
By Mahdi Islam, Musarrat Tabassum
Background Non-invasive presurgical diagnosis of brain tumor types from Magnetic Resonance Imaging (MRI) is essential but challenging due to overlapping imaging features across tumor types, inter-obse...
arXiv:2606. 19300v1 Announce Type: cross Abstract: Glioma segmentation in multiparametric MRI is a critical component of treatment planning.
By Xin Ci Wong, Duygu Sarikaya, Kieran Zucker, Marc De Kamps, Nishant Ravikumar
The paper introduces Observation‑Anchored Selective Assimilation (OASA) for forecasting tumor‑state proxies in post‑treatment glioma patients using serial MRI observations. OASA anchors the patient‑specific state with an intermediate observation and selectively updates it via a tiered rule and voxel‑wise soft gate, outperforming baseline methods in Dice score at certain thresholds. The approach is validated on 120 patient triplets and the code is publicly released.
By Yeonjae Jung, Minwoo Shin
arXiv:2609.15888v1 Announce Type: cross
Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
By Paul-Gabriel Nicolae, Irina Georgiana Mocanu
arXiv:2608.28714v1 Announce Type: cross
Abstract: Objective: Deep learning accelerates brain MRI four- to tenfold, but models can erase lesions or synthesize false tissue - failures pixel-averaged me...
By Dat Tat Mai, Thai Viet Pham, Thu Nguyen Thi Dang, James Jin Kang
The paper presents an optimal‑transport based generative model that learns the distributional differences between healthy and diseased patients, producing per‑patient counterfactuals and label‑free attribution heatmaps. On tabular breast cancer data the model achieves high malignancy scoring (AUROC ≈ 0.91) and its attributions correlate moderately with a supervised classifier, yet it does not surpass logistic regression. In chest X‑ray experiments the transport heatmaps capture population‑level signals but fail to localize real lesions, revealing a synthetic‑to‑real gap that challenges the reliability of label‑free explanations.
By Lalit Kumar