Multi-task learning for the automatic grading of enlarged perivascular space burden using MRI
Read the original on arXiv Machine Learning →The Flow has not summarised this story yet — read it at arXiv Machine Learning.
The Flow has not summarised this story yet — read it at arXiv Machine Learning.
The study evaluated a pragmatic deep‑learning approach for segmenting acute ischemic stroke lesions on diffusion‑weighted MRI. Using a self‑configured nnU‑Net trained on 1,744 cases and tested on 436, the baseline model achieved a median Dice similarity coefficient of 0.84, outperforming the DeepISLES ensemble, especially for smaller infarcts. The approach required minimal preprocessing and fast inference, suggesting it could streamline clinical stroke imaging workflows.
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The paper introduces AURA, an nnU-Net-based asymmetric supervision strategy for segmenting ultra‑low‑field (0.064 T) pediatric brain MRI. It treats high‑field‑derived (HF) and low‑field‑edited (LF) annotations as distinct observations, anchoring training to the HF mask while gating LF contributions through a reliability mechanism. On a 16‑case development split, AURA achieved Dice scores comparable to HF‑only training and improved boundary metrics, demonstrating its potential for ULF MRI segmentation.
The study presents an explainable multimodal deep‑learning framework that combines a 3D CNN for T1‑weighted MRI with a feedforward network for harmonized clinical and demographic data to diagnose Alzheimer’s disease. Using 6,479 ADNI records and 1,703 OASIS‑3 records, the authors compare various model configurations on three‑way and pairwise diagnostic tasks, finding that performance and explanations vary by task, modality, fusion strategy, and cohort. SHAP and Integrated Gradients consistently highlight the MMSE score as the most influential tabular feature, while CAM‑based explanations differ across model setups and cohorts, indicating that explainability is not a stable property under cohort shift.