arXiv:2608.28714v1 Announce Type: cross Abstract: Objective: Deep learning accelerates brain MRI four- to tenfold, but models can erase lesions or synthesize false tissue - failures pixel-averaged me...
The study presents an explainable multimodal deep‑learning framework that combines a 3D CNN for T1‑weighted MRI with a feedforward network for harmonized clinical and demographic data to diagnose Alzheimer’s disease. Using 6,479 ADNI records and 1,703 OASIS‑3 records, the authors compare various model configurations on three‑way and pairwise diagnostic tasks, finding that performance and explanations vary by task, modality, fusion strategy, and cohort. SHAP and Integrated Gradients consistently highlight the MMSE score as the most influential tabular feature, while CAM‑based explanations differ across model setups and cohorts, indicating that explainability is not a stable property under cohort shift.
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
The study presents a multimodal BrainAGE framework that fuses structural T1-weighted MRI with DeepCBV maps—vascular information synthesized from non‑contrast MRI—to estimate brain age more accurately. Using two separate 3D convolutional neural networks, the combined model achieved a mean absolute error of 3.95 years on cognitively normal controls, outperforming single‑modality models. Saliency analyses showed MRI highlighted white matter and cortical atrophy, while DeepCBV emphasized vascular‑rich regions, and the integrated approach revealed stronger differentiation between stable and progressive MCI, indicating sensitivity to early vascular changes.
arXiv:2607. 08595v1 Announce Type: new Abstract: Cardiovascular disease risk prediction models often rely on data from a single institution or centrally pooled datasets.
arXiv:2609.37387v1 Announce Type: cross Abstract: Enlarged perivascular spaces (PVS) visible in brain magnetic resonance imaging (MRI) are increasingly thought to be linked to poor brain health. PVS...
arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.
arXiv:2509. 10517v3 Announce Type: replace Abstract: Machine learning can predict in-hospital mortality, but data privacy and the statistical heterogeneity of clinical data hamper its use.
The paper presents an intelligent system that predicts stroke risk using eleven clinical features and evaluates seven supervised machine learning algorithms. Ensemble methods—Random Forest, Stacking Classifier, and Bagging Classifier—achieved the highest accuracies, reaching 99.52%, while other models such as KNN, TabNet, and a custom feedforward network also performed well. The study demonstrates that ensemble approaches are particularly effective for stroke classification tasks.
Deep learning models for neuroimaging have largely been developed for individual tasks, limiting knowledge transfer across applications. Here we introduce GenFAR, a modular deep learning framework that learns general, clinically informed features from brain MRIs.
The paper introduces the first federated learning framework for infant movement analysis, specifically targeting General Movement Assessment using skeletal motion data. It employs Monte Carlo Dropout to estimate predictive uncertainty and proposes an Uncertainty-Aware Federated Averaging (UA‑FedAvg) strategy that weights client updates by this uncertainty. Experiments with three clients show that federated learning outperforms local models and approaches centralized training performance, with UA‑FedAvg generally surpassing standard FedAvg.
arXiv:2504. 06299v2 Announce Type: replace-cross Abstract: Multimodal prediction models based on imaging and clinical data are increasingly used for clinical decision support, yet their interpretability remains limited.