arXiv:2608. 05244v1 Announce Type: cross Abstract: We developed a unified covariate-adjusted causal inference framework for estimating the desirability of outcome ranking (DOOR) probability for benefit-risk evaluation in randomized trials and observational studies.
arXiv:2606. 17113v1 Announce Type: new Abstract: Distinguishing causal adverse drug events (ADEs) from spurious correlations remains a central challenge in pharmacovigilance.
arXiv:2604. 16763v3 Announce Type: replace Abstract: Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from structured data.
arXiv:2608. 19383v1 Announce Type: cross Abstract: Average dose-response functions are widely used to summarize causal effects of continuous treatments, but most existing methods assume that the observed sample represents the target population.
arXiv:2606. 03332v1 Announce Type: new Abstract: Probabilistic models are typically trained using task-agnostic objectives like log-loss, which can lead to significant errors in downstream estimation.
arXiv:2608. 19501v1 Announce Type: cross Abstract: Diagnostic medical tests and devices provide useful information for evaluating the potential benefits and risks of therapeutic treatments.
arXiv:2609.00071v1 Announce Type: new Abstract: Prediction error is widely used to evaluate nuisance-function estimators in causal inference, but its relationship with causal estimator performance ma...
The paper introduces a new framework for identifying average dose-response functions in the presence of unmeasured confounding by using instrumental variables. It defines a uniform regular weighting function and partitions the treatment space into open sets where local identification is possible. For estimation, the authors propose an augmented inverse probability weighted score within a debiased machine learning setting, along with practical guidance for constructing weighting functions, falsification tests for the additive IV condition, and asymptotic theory for kernel regression or empirical risk minimization estimators.
arXiv:2607. 26521v1 Announce Type: new Abstract: Conventional subgroup analyses can yield unstable and difficult-to-interpret conclusions, especially in observational biomedical data where each individual is observed under only one exposure state, true individual treatment effects are unavailable, and causal structure is uncertain.
arXiv:2609.17238v1 Announce Type: cross Abstract: High-dimensional data create challenges for causal effect estimation because identifying the covariates needed for correct model specification become...
arXiv:2609.22383v1 Announce Type: cross Abstract: Instrumental variable (IV) methods address treatment endogeneity, but with non-compliance and heterogeneous treatment effects a binary instrument gen...
arXiv:2606. 01184v1 Announce Type: cross Abstract: Many interventions alter the structure of an outcome distribution rather than its mean: they can split a population into disconnected regimes, create loops or holes, generate branches, or reorganize an outcome cloud while leaving the average response nearly unchanged.
arXiv:2607. 22762v1 Announce Type: cross Abstract: Causal inference has become a central issue across various fields, including computer science, statistics, economics, education, healthcare, and medicine.