arXiv:2607. 26521v1 Announce Type: new Abstract: Conventional subgroup analyses can yield unstable and difficult-to-interpret conclusions, especially in observational biomedical data where each individual is observed under only one exposure state, true individual treatment effects are unavailable, and causal structure is uncertain.
arXiv:2606. 19092v1 Announce Type: cross Abstract: Chronic disease management relies on regular patient-provider interactions to follow-up on disease progression and control.
arXiv:2605. 13430v3 Announce Type: replace-cross Abstract: Selection bias is pervasive in observational studies.
arXiv:2604. 16763v3 Announce Type: replace Abstract: Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from structured data.
arXiv:2606. 08305v1 Announce Type: cross Abstract: Externally controlled survival trials are increasingly used when concurrent randomized controls are infeasible, particularly in oncology and rare-disease settings with time-to-event endpoints.
arXiv:2606. 30702v1 Announce Type: cross Abstract: Structured tabular data dominates clinical medicine, yet existing benchmarks fail to reflect real-world properties like complex survey sampling, demographic oversampling, and subgroup fairness.
arXiv:2608. 05244v1 Announce Type: cross Abstract: We developed a unified covariate-adjusted causal inference framework for estimating the desirability of outcome ranking (DOOR) probability for benefit-risk evaluation in randomized trials and observational studies.
arXiv:2607. 27224v1 Announce Type: cross Abstract: External and synthetic control arms (ECAs) are entering psychiatric drug development, but the field lacks a benchmark that evaluates the properties regulators care about: not only how accurately a method reconstructs untreated trajectories, but whether its uncertainty is calibrated, whether it is robust to the informative observation times common in mental-health records (sicker patients are seen more often), and what false-positive rate it induces in go/no-go trial decisions.
arXiv:2606. 01184v1 Announce Type: cross Abstract: Many interventions alter the structure of an outcome distribution rather than its mean: they can split a population into disconnected regimes, create loops or holes, generate branches, or reorganize an outcome cloud while leaving the average response nearly unchanged.
arXiv:2607. 05620v1 Announce Type: cross Abstract: In many decision-making settings, new interventions are acceptable only if they do not reduce outcomes below some established threshold.
arXiv:2504. 20908v3 Announce Type: replace Abstract: Current subgroup identification methods typically follow a two-step approach: first estimate conditional average treatment effects and then apply thresholding or rule-based procedures to define subgroups.
arXiv:2510. 19893v2 Announce Type: replace Abstract: Medical AI systems demonstrated impressive diagnostic performance, yet they routinely show uneven accuracy across demographic groups, disadvantaging underrepresented populations.
arXiv:2607. 15446v1 Announce Type: new Abstract: The cost of healthcare remains a concern in the United States and may have been influenced by disruptions associated with the COVID-19 pandemic.