arXiv Computer Vision

Universal Drift Correction for Multidimensional Scanning Microscopy

arXiv Computer Vision
Sep 23

Real-Time Atomic-Resolution Electron Phase Imaging without Probe Calibration via Ptychography-Supervised Learning

The paper introduces a ptychography‑supervised learning framework that transforms 4D‑STEM data into real‑time atomic‑resolution phase images. By training a compact model on physics‑constrained reference phase maps from a single AuPd dataset, the method predicts local phase patches directly from diffraction patterns without probe calibration or iterative optimization. The resulting workflow achieves an online latency of ~0.27 ms per probe position, a 1,000‑fold speed‑up over GPU‑accelerated ePIE, and maintains atomic‑scale lattice contrast while generalizing across materials, defocus conditions, and instruments.

By H. Yue, C. -C. Chen, C. -N. Hsiao, J. Cheng, Y. Liu, X. Z. Liao, Steve F. Shu
arXiv Computer Vision
Sep 1

Compact Snapshot Spectral Imaging with Calibration-Free Aperture Diffraction

The paper introduces ADIS, a compact, cost‑effective, calibration‑free snapshot spectral imaging system that uses only a diffractive lens, a binary mask, and a Bayer‑filtered sensor. ADIS disperses and multiplexes wavelengths, mapping energy to distinct sensor locations, and employs theoretically computed PSFs for calibration‑free spectral reconstruction. The authors further present the Orthogonal Diffraction‑Aware Unfolding Voxel Shift Transformer (ODAUVST) to solve the sparsely‑constrained inverse problem, achieving full‑resolution recovery with reduced parameters and demonstrating superior performance in real SSI experiments.

By Tao Lv, Quan Yuan, Shiqiao Li, Chenglong Huang, Linsen Chen, Chongde Zi, Shuming Wang, Xun Cao
arXiv Machine Learning
Jun 10

Unsupervised Deep Learning for Limited-Angle STEM-EDX Tomography -- Application to 3D Chemical Analysis of Phase-Change Memory Devices

arXiv:2606. 10547v1 Announce Type: cross Abstract: Energy Dispersive X-ray (EDX) tomography in Scanning Transmission Electron Microscopy (STEM) enables 3D compositional and elemental mapping at the nanoscale, but its use is limited by restricted tilt ranges and low-dose conditions required to avoid beam damage.

By Daniel del Pozo Bueno, Serge Brosset, Theo Monniez, Gabriele Navarro, Philippe Ciuciu, Zineb Saghi
arXiv Machine Learning
Aug 11

Multitask Scanning Probe Microscopy

arXiv:2608. 09104v1 Announce Type: cross Abstract: Scanning probe microscopy provides nanoscale access to structural, electrical, electromechanical, magnetic, and mechanical properties of materials.

By Aditya Raghavan, Yu Liu, Ian Mercer, JP Maria, Sergei Kalinin
arXiv Machine Learning
Sep 14

A unified self-supervised framework for single-frame Fresnel CDI and overlapped ptychography

The paper introduces a self‑supervised neural network that unifies single‑frame Fresnel coherent diffraction imaging (CDI) and overlapped ptychography. By using a fixed, pre‑estimated probe and optimizing with a Poisson negative log‑likelihood objective, the method reconstructs object patches from either a single diffraction frame or multiple overlapping measurements, achieving high SSIM scores and a ten‑fold improvement in photon‑dose efficiency. Demonstrations on synthetic patterns and real datasets from APS and LCLS show robust, high‑throughput reconstructions, with a 36× speedup over iterative solvers for a 10,304‑frame workload.

By Oliver Hoidn, Steven Henke, Albert Vong, Aashwin Mishra, Apurva Mehta, Matthew Seaberg
arXiv Computer Vision
Aug 28

Differentiable Jitter Correction using Deep Learning-based Image Quality Metric for Phase-Contrast Micro-CT

This paper introduces a fully differentiable jitter correction technique for X‑ray phase‑contrast micro‑CT that uses a deep learning‑based image quality metric to estimate and compensate per‑projection rigid jitter directly from the acquired data, eliminating the need for a motion‑free reference scan. The method adapts a gradient‑based auto‑focus strategy to parallel‑beam geometry, benchmarks several objective functions, and validates the sensitivity of the visual information fidelity (VIF) metric to jitter artifacts. A compact 3D CNN predicts VIF scores from corrupted volumes, while a spatially selective total variation penalty suppresses spurious high‑frequency structures during optimization; experiments on biological specimens from multiple synchrotron beamlines confirm that the pipeline reliably restores fine structural detail across morphologically distinct samples.

By Junan Chen, Yiting Jia, Joscha Maier, Dominik John, Sami Wirtensohn, Imke Greving, Silja Flenner, Matthias Wieczorek, Julia Herzen
arXiv AI
Jul 21

CORE -- A Cell-Level Coarse-to-Fine Image Registration Engine for Multi-stain Image Alignment

arXiv:2511. 03826v4 Announce Type: replace-cross Abstract: Accurate and efficient registration of whole slide images (WSIs) is essential for high-resolution, nuclei-level analysis in multi-stained tissue slides.

By Esha Sadia Nasir, Behnaz Elhaminia, Mark Eastwood, Catherine King, Owen Cain, Lorraine Harper, Paul Moss, Dimitrios Chanouzas, David Snead, Nasir Rajpoot, Adam Shephard, Shan E Ahmed Raza
arXiv Machine Learning
Aug 11

Beyond Isotropic Assumptions: Continuity-Constrained Segmentation and GPU Morphometry for Nanoscale GBM Analysis

arXiv:2608. 07575v1 Announce Type: cross Abstract: Confocal microscopy of optically cleared and swelled tissue resolves complex biological structures in 3D, but such acquisitions are highly anisotropic: along the under-sampled axial direction the structure can appear discontinuous, hampering reconstruction and automated quantitative analysis.

By Arash Fatehi, Robin Ebbestad, Linus Butt, Hans Blom, Sigrid Lundberg, Hannes Olauson, Hjalmar Brismar, David Unnersj\"o-Jess, Thomas Benzing, Katarzyna Bozek
arXiv Computer Vision
Sep 10

Advanced Brain Tissue Imaging with Data-Consistent Diffusion Priors in Laminographic X-Ray Nanoimaging

arXiv:2609.10456v1 Announce Type: new Abstract: Nanoscale imaging of mammalian brains is critical for connectomics. X-ray laminography enables high-throughput imaging of extended, plate-like biologic...

By Wenxuan Fang, Abraham L. Levitan, Ana Diaz, Carles Bosch, Adrian Wanner, Andreas T. Schaefer, Mirko Holler, Tomas Aidukas, Nicholas W. Phillips, Yuxin Zhang, Alexandra Pacureanu, Manuel Guizar-Sicairos, Luis Barba