The paper introduces a deep dictionary network (DDN) foundation model designed for ultra‑low‑dose CT (ULDCT) denoising across multiple organs. By cascading convolutional sparse coding layers with iterative soft‑thresholding, the architecture offers inherent interpretability, while dynamic dictionary and threshold modules enhance representation. The model is pre‑trained on over one million normal‑dose CT images and fine‑tuned on multi‑organ ULDCT datasets, achieving state‑of‑the‑art performance that consistently outperforms existing methods.
arXiv:2508.17299v2 Announce Type: replace Abstract: Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despi...
arXiv:2602. 21987v3 Announce Type: replace-cross Abstract: Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or scanner limitations, affecting both clinical interpretation and downstream analysis.
arXiv:2607. 11941v1 Announce Type: cross Abstract: Computed tomography (CT) is a critical imaging modality for clinical diagnosis, but reducing radiation dose inevitably introduces severe noise and structured artifacts that degrade image quality.
arXiv:2608.13791v2 Announce Type: replace-cross Abstract: Positron emission tomography (PET) imaging suffers from limited spatial resolution and low signal-to-noise ratio, which can compromise quanti...
arXiv:2608. 15246v1 Announce Type: cross Abstract: Sparse-view computed tomography (CT) reduces radiation dose by acquiring fewer projection views, but the resulting inverse problem is highly ill-posed and often produces severe streak artifacts.
Most existing deep learning-based PET image denoising methods assume a fixed and known dose reduction factor (DRF) for low-dose PET images. However, these methods encounter significant performance degradation when the DRF varies beyond the assumed one in practical applications.
Noise2Match is a self‑supervised method for low‑dose CT denoising that uses an adaptive inter‑slice matching network to model and correct the label transition between adjacent slices. By ensuring the equal‑mean condition of the Noise2Noise framework, it theoretically matches supervised training with paired noisy‑clean data. The approach also extends effectively to low‑dose cone‑beam CT, outperforming existing image‑domain self‑supervised methods.
arXiv:2608.10343v2 Announce Type: replace Abstract: While deep learning-based denoising has become widely adopted in low-dose CT, conventional models use generic architectures designed for natural im...
The paper introduces a one‑pass conditional 3D rectified flow (3D Flow) framework for denoising whole‑body PET images, employing an optimized non‑uniform sampling strategy and a linear‑interpolant velocity‑matching objective. It reconstructs a full 3D volume in about 30 seconds, dramatically faster than multi‑hour 3D diffusion models, while maintaining high global image quality and lesion conspicuity even at ultra‑low doses (down to 1/100 of standard). Zero‑shot transfer tests on independent clinical data demonstrate robust performance across datasets and unseen dose levels.
arXiv:2609.12860v1 Announce Type: new Abstract: Computed tomography (CT) and positron emission tomography (PET) provide complementary anatomical and functional information for cancer diagnosis and tr...
The paper introduces Conditional Diffusion Posterior Alignment (CDPA), a method that scales diffusion-based sparse‑view CT reconstruction to large 3D volumes by conditioning a 2D U‑Net diffusion model on an initial 3D reconstruction and enforcing data‑consistency alignment. CDPA addresses high memory demands, limited 3D training data, and slice‑wise inconsistencies, achieving state‑of‑the‑art performance on synthetic and real Cone Beam CT data. The authors also demonstrate that the same approach improves fast denoising U‑Nets, delivering near‑diffusion quality at a fraction of the computational cost.
nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.