arXiv:2508.17299v2 Announce Type: replace
Abstract: Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despi...
By Zhihao Chen, Qi Gao, Zilong Li, Junping Zhang, Yi Zhang, Jun Zhao, Hongming Shan
The paper introduces Dose-Aware Cold Diffusion (DACD), a physics-consistent framework that treats radiation dose as a continuous latent variable in a cold diffusion process for low-dose CT reconstruction. DACD combines dose-aware perception, multi-scale structural priors, and dose-calibrated step allocation to guide denoising, and adds an iterative forward-backprojection correction to enforce projection-domain consistency. Experiments on Mayo-2020, Mayo-2016, and LoDoPaB-CT show DACD outperforms existing diffusion-based and physics-guided methods, especially at ultra-low doses, and generalizes robustly across continuous, unseen dose levels.
By Md Imam Ahasan, Guangchao Yang, A F M Abdun Noor, S M Hasan Mahmud, Md Mahfuzur Rahman
arXiv:2608. 08919v1 Announce Type: cross Abstract: During standard radiotherapy planning, repeated CT acquisitions are often required for patient registration, verification, and adaptive planning, resulting in increased cumulative X-ray dose.
By Alzahra Altalib, Chunhui Li, Christopher Hamill Taylor, Sankar Pillai, Alessandro Perelli
arXiv:2509. 21913v2 Announce Type: replace-cross Abstract: Background: Cone-beam computed tomography CBCT is a commonly used modality for image guided radiotherapy.
By Alzahra Altalib, Chunhui Li, Alessandro Perelli
The paper introduces Conditional Diffusion Posterior Alignment (CDPA), a method that scales diffusion-based sparse‑view CT reconstruction to large 3D volumes by conditioning a 2D U‑Net diffusion model on an initial 3D reconstruction and enforcing data‑consistency alignment. CDPA addresses high memory demands, limited 3D training data, and slice‑wise inconsistencies, achieving state‑of‑the‑art performance on synthetic and real Cone Beam CT data. The authors also demonstrate that the same approach improves fast denoising U‑Nets, delivering near‑diffusion quality at a fraction of the computational cost.
By Luis Barba, Johannes Kirschner, Benjamin Bejar
The paper introduces a high‑resolution Rectified Flow Matching model trained on 256×256 chest CT images to serve as a generative prior for CT reconstruction. A two‑stage training strategy—initial strong anatomically informed augmentation followed by fine‑tuning—helps mitigate overfitting and improve structural fidelity. When evaluated on various CT inverse problems, Flow Matching‑based reconstruction methods outperform diffusion‑based algorithms in PSNR, SSIM, and perceptual quality while requiring fewer sampling steps.
By Davide Evangelista
The paper introduces a deep dictionary network (DDN) foundation model designed for ultra‑low‑dose CT (ULDCT) denoising across multiple organs. By cascading convolutional sparse coding layers with iterative soft‑thresholding, the architecture offers inherent interpretability, while dynamic dictionary and threshold modules enhance representation. The model is pre‑trained on over one million normal‑dose CT images and fine‑tuned on multi‑organ ULDCT datasets, achieving state‑of‑the‑art performance that consistently outperforms existing methods.
By Baoshun Shi, Shuangyi Yang, Ke Jiang, Bin Zhu, Zhanli Hu, Huazhu Fu
The paper introduces a one‑pass conditional 3D rectified flow (3D Flow) framework for denoising whole‑body PET images, employing an optimized non‑uniform sampling strategy and a linear‑interpolant velocity‑matching objective. It reconstructs a full 3D volume in about 30 seconds, dramatically faster than multi‑hour 3D diffusion models, while maintaining high global image quality and lesion conspicuity even at ultra‑low doses (down to 1/100 of standard). Zero‑shot transfer tests on independent clinical data demonstrate robust performance across datasets and unseen dose levels.
By Jiale Shen, Guolin Wang, Chenhao Wang, Xinhui Su, Wei Luo, Feng Yu
The paper proposes a single diffusion model trained across multiple imaging domains to act as a reusable prior for computed tomography (CT) reconstruction. By keeping the model frozen, it is applied to three distinct datasets—flaw analysis in additively manufactured metal parts using cone‑beam X‑ray CT, and concrete microstructure imaging with parallel‑beam neutron CT—each differing in modality, geometry, material, and degradation. In all cases, the method outperforms analytic reconstructions, demonstrating its potential as a foundation plug‑and‑play prior for heterogeneous CT problems.
By Haley Duba-Sullivan, Patxi Fernandez-Zelaia, Obaidullah Rahman, Amirkoushyar Ziabari
arXiv:2606. 16212v1 Announce Type: cross Abstract: Sparse-view CT reduces radiation dose and scanning time by acquiring fewer projection views, but angular undersampling makes reconstruction severely ill-posed, causing streak artifacts, structural blurring, and loss of fine details.
By Jigang Duan, Jiayi Wang, Heran Wang, Ping Yang, Genwei Ma, Xing Zhao
arXiv:2608. 15246v1 Announce Type: cross Abstract: Sparse-view computed tomography (CT) reduces radiation dose by acquiring fewer projection views, but the resulting inverse problem is highly ill-posed and often produces severe streak artifacts.
By Tran Xuan Hieu Le, Doanh C. Bui, Vu Trung Duong Le, Hoai Luan Pham, Khang Nguyen, Mai K. Nguyen, Tu Bao Ho, Yasuhiko Nakashima
arXiv:2605.20470v2 Announce Type: replace-cross
Abstract: Cone-beam CT (CBCT) is routinely acquired during radiotherapy for patient setup, but its quantitative reliability is degraded by scatter, noi...
By Alzahra Altalib, Chunhui Li, Haytham Ahmad Alewaidat, Khaled Z. Alawneh, Ahmad Awad Qandeel, Alessandro Perelli