arXiv Computer Vision

nnFoundation: 3D Foundation Models for Radiology

nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.

arXiv Computer Vision
Aug 25

Expert-level vision-language foundation model for real-world radiology and comprehensive evaluation

arXiv:2409.16183v2 Announce Type: replace Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...

By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
arXiv Computer Vision
Sep 22

MTMed3D: A Multi-Task Transformer-Based Model for 3D Medical Imaging

MTMed3D is a multi-task Transformer-based model that jointly performs 3D detection, segmentation, and classification in medical imaging. It uses a shared Transformer encoder to produce multi-scale features, with separate CNN decoders for each task. Evaluated on BraTS 2018 and 2019, it achieves strong results, especially in detection, while reducing computational cost and inference time compared to single-task models.

By Fan Li, Arun Iyengar, Lanyu Xu
arXiv Computer Vision
Aug 28

Unsupervised Adaptation of 3D CT Foundation Models for 3D CBCT Segmentation

The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.

By Gauthier Miralles, Loic Le Folgoc, Vincent Jugnon, Pietro Gori
arXiv Machine Learning
Aug 18

Comprehensive language-image pre-training for 3D medical image understanding

arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.

By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
arXiv AI
Aug 11

Resolution Meets Reduction: Efficient Visual Context for 3D Radiology Report Generation

arXiv:2608. 08713v1 Announce Type: cross Abstract: Vision-language models offer a promising path toward automating radiology report generation, but applying them to full 3D CT volumes poses substantial computational challenges.

By Jonathan Suprijadi, Raphael Stock, Moritz Langenberg, David Zimmerer, Kim-Celine Kahl, Stefan Denner, Yannick Kirchhoff, Karol Gotkowski, Maximilian Rokuss, Jeremias Traub, Tassilo Wald, Constantin Ulrich, Klaus Maier-Hein
arXiv AI
Jul 9

Vision Foundation Models in Radiology: A Scoping Review of Data, Methodology, Evaluation and Clinical Translation

arXiv:2607. 07219v1 Announce Type: cross Abstract: Vision foundation models (VFMs) are increasingly being developed for radiological imaging, yet their definition, development and evaluation remain heterogeneous.

By Alejandro Vergara-Richart (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain, Universitat Polit\`ecnica de Val\`encia, Val\`encia, Spain), Xavier Rafael-Palou (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain), Almudena Fuster-Matanzo (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain), Ignacio Iborra Roncales (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain), \'Angel Alberich-Bayarri (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain), Ana Jim\'enez-Pastor (Quantitative Imaging Biomarkers in Medicine, Quibim S.L., Val\`encia, Spain)
arXiv Machine Learning
Jun 3

GLINT: Sparsely Gated Vision-Language Alignment for Fine-Grained Radiology Representations

arXiv:2606. 03180v1 Announce Type: cross Abstract: Vision-language models (VLMs) for radiology have emerged as a scalable paradigm by leveraging image-report pairs naturally produced in clinical workflows.

By Jonggwon Park, Seongeun Lee, Junhyun Park, Hannah Yun, Hyunwoong Kim, Sohyun Jeong, Hyewon Kang, Byungmu Yoon, Kyoyun Choi
arXiv AI
Aug 11

Compositional Cross-Modality Translation via Whole-Volume Multitask Latent Flow Matching

arXiv:2608. 08135v1 Announce Type: cross Abstract: Cross-modality medical image translation can reduce the burden of multi-modal acquisitions, yet the field remains constrained by two coupled limitations: methods operate on 2D slices or 3D patches rather than whole volumes, and train a separate model for each translation task.

By Daniele Molino, Alessio Zoboli, Camillo Maria Caruso, Valerio Guarrasi, Paolo Soda
arXiv Computer Vision
Sep 15

Designing UNICORN: a Unified Benchmark for Imaging in Computational Pathology, Radiology, and Natural Language

arXiv:2603.02790v2 Announce Type: replace Abstract: Foundation models are changing the way we develop medical artificial intelligence. By learning broadly generalizable features across diverse data m...

By Michelle Stegeman (and on behalf of the UNICORN consortium), Lena Philipp (and on behalf of the UNICORN consortium), Fennie van der Graaf (and on behalf of the UNICORN consortium), Marina D'Amato (and on behalf of the UNICORN consortium), Cl\'ement Grisi (and on behalf of the UNICORN consortium), Luc Builtjes (and on behalf of the UNICORN consortium), Joeran S. Bosma (and on behalf of the UNICORN consortium), Judith Lefkes (and on behalf of the UNICORN consortium), Rianne A. Weber (and on behalf of the UNICORN consortium), James A. Meakin (and on behalf of the UNICORN consortium), Thomas Koopman (and on behalf of the UNICORN consortium), Anne Mickan (and on behalf of the UNICORN consortium), Mathias Prokop (and on behalf of the UNICORN consortium), Ewoud J. Smit (and on behalf of the UNICORN consortium), Fr\'ed\'erique Meeuwsen (and on behalf of the UNICORN consortium), Geert Litjens (and on behalf of the UNICORN consortium), Jeroen van der Laak (and on behalf of the UNICORN consortium), Bram van Ginneken (and on behalf of the UNICORN consortium), Maarten de Rooij (and on behalf of the UNICORN consortium), Henkjan Huisman (and on behalf of the UNICORN consortium), Colin Jacobs (and on behalf of the UNICORN consortium), Francesco Ciompi (and on behalf of the UNICORN consortium), Alessa Hering (and on behalf of the UNICORN consortium)