The paper introduces PRISM, a Compositional Reward Model framework that decomposes image quality into multiple verifier‑grounded stages for conditional medical image generation. By assigning distinct rewards for fine‑to‑coarse properties—such as intensity, texture, structural alignment, and semantic fidelity—and combining them via a Hierarchical Constrained Propagation mechanism, PRISM addresses shortcomings of single‑scalar reward approaches. Experiments on PanNuke, CeDeM, and ISIC datasets show that data generated with PRISM improves downstream model performance, achieving higher mDice, lower MRE, and increased F1 scores compared to baseline methods.
By Aayush Kumar Tyagi, Prathosh A. P., Mausam
The study examines how three parameter‑efficient adaptation methods—linear heads on the raw CLS token, an MLP, and an attention‑pooling module—affect pathology classification accuracy and subgroup fairness when applied to a frozen Rad‑DINO chest X‑ray encoder. Using the MIMIC‑CXR dataset, the authors evaluate eight pathologies across race, sex, and imaging‑view subgroups, finding that attention pooling yields the best overall performance and encodes protected attributes most strongly, yet higher performance does not consistently reduce subgroup disparities. The results show that attribute encoding strength and layer choice do not reliably predict fairness outcomes, indicating that fairness must be assessed directly for each task.
By Dhruv Gupta, Emma A. M. Stanley, Fabio De Sousa Ribeiro, Sujal R. Desai, Ben Glocker
arXiv:2607. 03103v1 Announce Type: cross Abstract: Clinical cardiac imaging pipelines currently deploy separate models for each dataset and modality, incurring redundant training costs and precluding knowledge sharing across anatomically related tasks.
By Jiahao Liu, Hang Wei, Shuai Wu
The paper presents a method for generating cardiac magnetic resonance (CMR) images conditioned on patient metadata using a pretrained latent diffusion model. By encoding structured clinical data and slice position as textual prompts and applying Metadata‑Free Classifier‑Free Guidance, Contrastive Batching, and Inverse‑Frequency Sampling, the authors improve the fidelity of synthetic images, achieving a 57% reduction in Fréchet Inception Distance compared to a baseline without these strategies. Evaluation on 59,058 UK Biobank CMR scans shows better distributional realism and subgroup alignment, though disease‑specific conditioning remains challenging.
By Marc Rodr\'iguez, Grzegorz Skorupko, Nay Aung, Steffen E Petersen, Karim Lekadir, Polyxeni Gkontra
arXiv:2607. 14984v1 Announce Type: new Abstract: Per-subgroup fairness audits of medical image classifiers face a sample-size problem: minority subgroups in held-out test sets have so few samples that the resulting confidence intervals on per-subgroup performance are wider than the bias the audit is meant to detect.
By Mahmoud Ibrahim, Bart Elen, Chang Sun, Gokhan Ertaylan, Michel Dumontier
arXiv:2609.14124v1 Announce Type: cross
Abstract: Medical image analysis is often hindered by biased datasets, which can lead to biased models and limited clinical applicability. A promising strategy...
By Yasin Ibrahim, Robin J. Evans, Konstantinos Kamnitsas
UniH$^3$ is a new framework for all-in-one medical image restoration that unifies hierarchical homogeneity and heterogeneity. It introduces a Hierarchical Homogeneity Memory (H2M) module to distill and retrieve shared anatomical priors, and a Hierarchical Heterogeneity Balancer (H2B) to mitigate inter- and intra-task conflicts during training. Experiments on MedIR-2D-500K and MedIR-3D-3K show that UniH$^3$ achieves state‑of‑the‑art performance for both multi‑task and single‑task restoration.
By Zhiwen Yang, Jiayin Li, Chengyu Liu, Hui Zhang, Bingzheng Wei, Yan Xu
arXiv:2607. 02998v2 Announce Type: replace-cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.
By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv:2608. 07340v1 Announce Type: cross Abstract: Registration-based Few-shot medical image segmentation (RFMIS) aims to generate pseudo-labels for unlabeled images by warping a labeled image through registration.
By Jia Wang, Jiaming Cai, Zunying Hu, Zhanjie Wu, Jinyuan Liu, Hua Cheng, Yun Peng
arXiv:2510. 19893v2 Announce Type: replace Abstract: Medical AI systems demonstrated impressive diagnostic performance, yet they routinely show uneven accuracy across demographic groups, disadvantaging underrepresented populations.
By Shiqi Dai, Wei Dai, Jiaee Cheong, Paul Pu Liang
arXiv:2607. 02998v1 Announce Type: cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.
By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv:2504. 19621v2 Announce Type: replace Abstract: Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance.
By Haroui Ma, Francesco Quinzan, Theresa Willem, Stefan Bauer