arXiv:2609.00396v1 Announce Type: new
Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
By Chad Wong, Sicheng Chen, Tianyi Zhang, Enhui Chai, Yueming Jin, Zeyu Liu, Fei Xia
Whole slide images (WSIs) in digital histopathology are acquired at discrete magnification levels encoding complementary diagnostic information from global tissue architecture to fine-grained cellular morphology. Yet, deep learning models remain sensitive to scale variation.
arXiv:2607. 10783v1 Announce Type: cross Abstract: Whole-slide images (WSIs) provide rich tissue-level and cellular-level information, but storing and transmitting high-magnification pathology data is resource-intensive.
By Dung Minh Do, Nhat-Thanh Huynh, Duc Minh Huynh, Doanh C. Bui, Khang Nguyen
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat
arXiv:2512. 21414v2 Announce Type: replace-cross Abstract: Recent tool-use frameworks powered by vision-language models (VLMs) improve image understanding by grounding model predictions with specialized tools.
By Christina Liu, Alan Q. Wang, Joy Hsu, Jiajun Wu, Ehsan Adeli
arXiv:2511.22232v2 Announce Type: replace-cross
Abstract: Multimodal large language models (MLLMs) are increasingly capable in medical imaging, yet most focus on single-image settings. Clinical inter...
By Zhen Chen, Yihang Fu, Rong Zhou, Serina Applebaum, Min Kyu Kim, Aidan Gilson, Morten Lee, Salahudeen Mirza, Gabriel Madera, Mauro Giuffre, Yuanting Pan, Roy Jiang, Hyunjae Kim, Hua Xu, Qingyu Chen
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
AtlasPatch is a scalable, high‑throughput whole‑slide image preprocessing method that uses a foundation‑model‑based tissue detector operating at thumbnail resolution. By updating only 0.076% of the SAM2 model weights and leveraging a curated dataset of 30,000 thumbnail‑mask pairs, it generates accurate tissue masks and directly produces patch coordinates at the desired magnification, eliminating repeated patch‑level inference. The approach achieves 0.986 precision, is up to 16× faster than existing deep‑learning methods, and maintains downstream multiple‑instance learning performance across six slide‑level classification tasks.
By Ahmed Alagha, Christopher Leclerc, Yousef Kotp, Omar Metwally, Calvin Moras, Peter Rentopoulos, Ghodsiyeh Rostami, Bich Ngoc Nguyen, Jumanah Baig, Abdelhakim Khellaf, Vincent Quoc-Huy Trinh, Rabeb Mizouni, Hadi Otrok, Jamal Bentahar, Mahdi S. Hosseini
arXiv:2607. 14703v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become the main paradigm for whole-slide image (WSI) analysis in computational pathology.
By Mingxi Fu, Jiawen Li, Renao Yan, Jiali Hu, Qiehe Sun, Tian Guan, Yonghong He
arXiv:2603.02790v2 Announce Type: replace
Abstract: Foundation models are changing the way we develop medical artificial intelligence. By learning broadly generalizable features across diverse data m...
By Michelle Stegeman (and on behalf of the UNICORN consortium), Lena Philipp (and on behalf of the UNICORN consortium), Fennie van der Graaf (and on behalf of the UNICORN consortium), Marina D'Amato (and on behalf of the UNICORN consortium), Cl\'ement Grisi (and on behalf of the UNICORN consortium), Luc Builtjes (and on behalf of the UNICORN consortium), Joeran S. Bosma (and on behalf of the UNICORN consortium), Judith Lefkes (and on behalf of the UNICORN consortium), Rianne A. Weber (and on behalf of the UNICORN consortium), James A. Meakin (and on behalf of the UNICORN consortium), Thomas Koopman (and on behalf of the UNICORN consortium), Anne Mickan (and on behalf of the UNICORN consortium), Mathias Prokop (and on behalf of the UNICORN consortium), Ewoud J. Smit (and on behalf of the UNICORN consortium), Fr\'ed\'erique Meeuwsen (and on behalf of the UNICORN consortium), Geert Litjens (and on behalf of the UNICORN consortium), Jeroen van der Laak (and on behalf of the UNICORN consortium), Bram van Ginneken (and on behalf of the UNICORN consortium), Maarten de Rooij (and on behalf of the UNICORN consortium), Henkjan Huisman (and on behalf of the UNICORN consortium), Colin Jacobs (and on behalf of the UNICORN consortium), Francesco Ciompi (and on behalf of the UNICORN consortium), Alessa Hering (and on behalf of the UNICORN consortium)
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
This study presents a clinically relevant framework for evaluating deep neural networks that segment lymphoma lesions in PET/CT images, addressing gaps such as out‑of‑distribution testing and comparison with expert annotators. Using 611 multi‑institutional cases, the authors assess four networks (ResUNet, SegResNet, DynUNet, SwinUNETR) with lesion‑specific metrics, detection criteria, and metabolic‑characteristic‑based thresholds, finding that models perform best on large, intense lesions. The work also demonstrates that network errors mirror those of physicians, highlighting shared challenges with small, faint lesions.
By Shadab Ahamed, Yixi Xu, Sara Kurkowska, Claire Gowdy, Joo H. O, Ingrid Bloise, Don Wilson, Patrick Martineau, Fran\c{c}ois B\'enard, Fereshteh Yousefirizi, Rahul Dodhia, Juan M. Lavista, William B. Weeks, Carlos F. Uribe, Arman Rahmim