arXiv Computer Vision

Designing UNICORN: a Unified Benchmark for Imaging in Computational Pathology, Radiology, and Natural Language

arXiv Computer Vision
Aug 25

Expert-level vision-language foundation model for real-world radiology and comprehensive evaluation

arXiv:2409.16183v2 Announce Type: replace Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...

By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
arXiv Machine Learning
Sep 24

FFM-CP: Cross-Backbone Fusion of Vision-Language Foundation Models for Few-Shot Computational Pathology

The paper introduces FFM-CP, a framework that fuses multiple pathology vision‑language foundation models for few‑shot learning. It aligns heterogeneous representations with an Orthogonal Procrustes transformation, then uses a unified graph to refine support‑image features and class prototypes across backbones. Experiments on six histopathology datasets show that FFM‑CP outperforms the best single adapted model in 50 of 54 few‑shot comparisons.

By Anh-Tien Nguyen, Trung DQ. Dang, Nghiem Tuong Diep, Bui Ngoc Han Nguyen, Tan-Ha Mai, Miriam Cindy Maurer, Phuong Hoa Nguyen, Thi Thuy Uyen Nguyen, Youngjun Park, Daniel Sonntag, Duy Minh Ho Nguyen, Anne-Christin Hauschild
arXiv Machine Learning
Jul 9

MedPMC: A Systematic Framework for Scaling High-Fidelity Medical Multimodal Data for Foundation Models

arXiv:2607. 07673v1 Announce Type: cross Abstract: Medicine is inherently multimodal, requiring clinicians to synthesize information across diverse data streams.

By Hyunjae Kim, Dain Kim, Pan Xiao, Serina S. Applebaum, Younjoon Chung, Xuguang Ai, Yu Yin, Roy Jiang, Yuexi Du, Yawen Wei, Yiming Kong, Tuo Guo, Zhiyuan Cao, Mengmeng Du, Yuelei Fu, Yan Hu, Rui Shi, Gui Yang, Kevin W. Jin, Yuntian Liu, Yuxuan Tian, Jonathan Marquez, Zhen Chen, Sheng Zhang, Hoifung Poon, Hua Xu, Jaewoo Kang, Qingyu Chen
Hugging Face Trending Papers
Jun 24

Disease-Centric Vision-Language Pretraining with Hybrid Visual Encoding for 3D Computed Tomography

Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.

arXiv AI
Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing
arXiv Computer Vision
Sep 3

AlphaRAD: Grounded Zero-Shot Classification in Chest Radiology via $\alpha$-Corrected Binary Cross Entropy and Factorized Latent Supervision

AlphaRAD introduces a grounded zero‑shot classification framework for chest radiology that leverages structured medical concepts extracted from reports and a novel α‑Corrected Binary Cross‑Entropy loss to reduce in‑batch noise. It also presents FLaS, a lightweight cross‑modal fusion module that factorizes VLPM representations into independent subspaces, improving spatial grounding without adding parameters. The method achieves state‑of‑the‑art performance on 16 classification benchmarks and sets new records on several grounding, phrase‑grounding, and segmentation datasets.

By Jianzhong You, Yuan Gao, Chris McIntosh
arXiv AI
Aug 5

CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement

arXiv:2608. 03890v1 Announce Type: cross Abstract: A clinically useful chest X-ray system must go beyond fluent report generation: it should classify findings with tunable decision thresholds, localize them spatially, and derive the anatomical measurements upon which many diagnoses depend.

By Mercy Prasanna Ranjit, Anirban Porya, Sathvik Joel, Niharika Vadlamudi, Nikhilesh Chowdary Eathamukkala, Prasanth V V, Abhyuday Kumara Swamy, Pranay Narhari Umredkar, Pradeep Narayan, Vivek Rajagopal, Tanuja Ganu
arXiv Computer Vision
Sep 24

nnFoundation: 3D Foundation Models for Radiology

nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.

By Constantin Ulrich Harsy, Tassilo Wald, Karol Gotkowski, Yannick Kirchhoff, Marcel Knopp, Maximilian Rokuss, Elisa Stegmeier, Philipp Schader, Dasha Trofimova, Raphael Stock, Kim-Celine Kahl, Stephen Schaumann, Selen Erkan, David Zimmerer, Stefan Denner, Moritz Langenberg, Sebastian Ziegler, Katharina Eckstein, Maximilian Fischer, Jonathan Suprijadi, B\'alint Kov\'acs, Benjamin Hamm, Anand Deshpande, Dimitrios Bounias, Nico Disch, Shuhan Xiao, Jessica K\"achele, Jan Sellner, Rajesh Baidya, Jeremias Traub, Lars Kr\"amer, Maximilian Zenk, Tim R\"adsch, Stefan Dvoretskii, Robin Peretzke, Jonathan Deissler, Alexandra Ertl, Partha Ghosh, Kris Dreher, Stefan Dinkelacker, Annika Reinke, Evangelia Christodoulou, Numan Saeed, Yoland Savriama, Santiago Estrada, David K\"ugler, Laura Alexandra Daza Barragan, Cristina Isabel Gonzalez Osorio, Jan Peeken, Michael Baumgartner, Marvin Teichmann, Guillaume Chabin, Matthias Kirchler, Valentin Koch, for the ALFA study, Markus Hohenhaus, Dimitri Koslov, Nina Decker, Mohammad Yaqub, Arnd Heuser, Martin Reuter, Julia A. Schnabel, Tobias Heimann, Florin Ghesu, Paul Brachmann, Claus P. Heu{\ss}el, Alexander Radbruch, Gianluca Brugnara, Aditya Rastogi, Martha Foltyn-Dumitru, Heinz-Peter Schlemmer, Ignaz Reicht, Julius C. Holzschuh, Michael Bach, Bram Stieltjes, Kai Schlamp, Lena Maier-Hein, Marco Nolden, Ralf Floca, Paul F. J\"ager, Philipp Vollmuth, Fabian Isensee, Klaus H. Maier-Hein
arXiv Computation and Language
Sep 22

MedGPT-oss: Training a General-Purpose Vision-Language Model for Biomedicine

arXiv:2603.00842v2 Announce Type: replace Abstract: Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remai...

By Kai Zhang, Zhengqing Yuan, Cheng Peng, Songlin Zhao, Mengxian Lyu, Ziyi Chen, Yanfang Ye, Wei Liu, Ying Zhang, Kaleb E Smith, Lifang He, Lichao Sun, Yonghui Wu