Whole slide images (WSIs) in digital histopathology are acquired at discrete magnification levels encoding complementary diagnostic information from global tissue architecture to fine-grained cellular morphology. Yet, deep learning models remain sensitive to scale variation.
arXiv:2609.00396v1 Announce Type: new
Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
By Chad Wong, Sicheng Chen, Tianyi Zhang, Enhui Chai, Yueming Jin, Zeyu Liu, Fei Xia
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
The paper introduces Segment Anything Small (SAS), a data‑augmentation method that improves deep‑learning segmentation of small anatomical structures in ultrasound images. SAS uses two transformations: resizing and embedding organ thumbnails into a black background to vary organ scale, and adding noise to regions of interest to mimic tissue texture variability. Experiments on one internal and five external datasets show Dice score gains up to 0.35, with an average improvement of 0.16, and demonstrate that SAS enhances model robustness and generalizability without adding hallucinations or artifacts.
By Danielle L. Ferreira, Ahana Gangopadhyay, Hsi-Ming Chang, Ravi Soni, Gopal Avinash
arXiv:2606. 06864v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become a standard paradigm for whole slide image (WSI) analysis in digital pathology, as it enables slide-level prediction without dense annotations.
By Yonghan Shin, Won-Ki Jeong
arXiv:2602. 21987v3 Announce Type: replace-cross Abstract: Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or scanner limitations, affecting both clinical interpretation and downstream analysis.
By Jitindra Fartiyal, Pedro Freire, Sergei K. Turitsyn, Sergei G. Solovski
arXiv:2608. 15915v1 Announce Type: cross Abstract: Lung cancer remains the leading cause of cancer-related mortality worldwide, while histopathological diagnosis is often affected by inter-observer variability and the substantial workload associated with manual slide examination.
By Hadi Hasan, Safaa Salman, Lama Sleem, Ralph Mouawad, Ali Chehab
arXiv:2601. 05148v2 Announce Type: replace-cross Abstract: Pathology foundation models substantially advanced the possibilities in computational pathology --- yet tradeoffs in terms of performance, robustness, and computational requirements remained, which limited their clinical deployment.
By Maximilian Alber, Timo Milbich, Alexandra Carpen-Amarie, Stephan Tietz, Jonas Dippel, Lukas Muttenthaler, Beatriz Perez Cancer, Alessandro Benetti, Panos Korfiatis, Elias Eulig, J\'er\^ome L\"uscher, Jiasen Wu, Sayed Abid Hashimi, Gabriel Dernbach, Simon Schallenberg, Neelay Shah, Moritz Kr\"ugener, Aniruddh Jammoria, Jake Matras, Patrick Duffy, Matt Redlon, Philipp Jurmeister, David Horst, Lukas Ruff, Klaus-Robert M\"uller, Frederick Klauschen, Andrew Norgan
arXiv:2507. 05077v5 Announce Type: replace-cross Abstract: Deep neural networks are increasingly applied in automated histopathology.
By Tarun Gogisetty, Naman Malpani, Gugan Thoppe, Sridharan Devarajan
arXiv:2607. 10783v1 Announce Type: cross Abstract: Whole-slide images (WSIs) provide rich tissue-level and cellular-level information, but storing and transmitting high-magnification pathology data is resource-intensive.
By Dung Minh Do, Nhat-Thanh Huynh, Duc Minh Huynh, Doanh C. Bui, Khang Nguyen
arXiv:2607. 14703v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become the main paradigm for whole-slide image (WSI) analysis in computational pathology.
By Mingxi Fu, Jiawen Li, Renao Yan, Jiali Hu, Qiehe Sun, Tian Guan, Yonghong He
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi