AtlasPatch is a scalable, high‑throughput whole‑slide image preprocessing method that uses a foundation‑model‑based tissue detector operating at thumbnail resolution. By updating only 0.076% of the SAM2 model weights and leveraging a curated dataset of 30,000 thumbnail‑mask pairs, it generates accurate tissue masks and directly produces patch coordinates at the desired magnification, eliminating repeated patch‑level inference. The approach achieves 0.986 precision, is up to 16× faster than existing deep‑learning methods, and maintains downstream multiple‑instance learning performance across six slide‑level classification tasks.
By Ahmed Alagha, Christopher Leclerc, Yousef Kotp, Omar Metwally, Calvin Moras, Peter Rentopoulos, Ghodsiyeh Rostami, Bich Ngoc Nguyen, Jumanah Baig, Abdelhakim Khellaf, Vincent Quoc-Huy Trinh, Rabeb Mizouni, Hadi Otrok, Jamal Bentahar, Mahdi S. Hosseini
arXiv:2607. 10783v1 Announce Type: cross Abstract: Whole-slide images (WSIs) provide rich tissue-level and cellular-level information, but storing and transmitting high-magnification pathology data is resource-intensive.
By Dung Minh Do, Nhat-Thanh Huynh, Duc Minh Huynh, Doanh C. Bui, Khang Nguyen
arXiv:2507. 05077v5 Announce Type: replace-cross Abstract: Deep neural networks are increasingly applied in automated histopathology.
By Tarun Gogisetty, Naman Malpani, Gugan Thoppe, Sridharan Devarajan
MagViT is an interpretable multi‑magnification transformer that classifies breast histopathology images by extracting representations from four BreakHis magnifications (40X, 100X, 200X, 400X) and fusing them with a learnable, scale‑gated mechanism that can mask missing scales. The model selects the most accurate architectural branch at the patient level using five‑fold cross‑validation, achieving high performance on BreakHis (mean image accuracy 0.9191, patient accuracy 0.9643, macro‑F1 0.9042) and demonstrating preliminary cross‑dataset generalization on BUSI and IDC. Grad‑CAM visualizations confirm that the network focuses on diagnostically relevant regions across magnifications.
By Nabil Ashab, Soumit Kumar Kundu, Saif Mahmud Parvez, Shahadat Hossain Sohag, Bidhan Biswas, Nazmus Subha
arXiv:2603.02843v2 Announce Type: replace
Abstract: Generalisation across image scales remains a fundamental challenge for deep networks, which often fail to handle images at scales not seen during t...
By Andrzej Perzanowski, Tony Lindeberg
The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.
By Young Seok Jeon, Beatrice Brown-Mulry, Rohan Satya Isaac, Anjana Dissanayaka, Theo Dapamede, Mohammadreza Chavoshi, Judy Gichoya, Hari Trivedi