Whole slide images (WSIs) in digital histopathology are acquired at discrete magnification levels encoding complementary diagnostic information from global tissue architecture to fine-grained cellular morphology. Yet, deep learning models remain sensitive to scale variation.
arXiv:2609.07313v1 Announce Type: new
Abstract: Segmentation of complex structures in X-ray tomographic data is a fundamental task in biomedical research, but it often requires large amounts of preci...
By Daniele Rusconi, Michela Ascolese, Stephanie Fest-Santini, Alberto Bravin, Maurizio Santini
arXiv:2507. 05077v5 Announce Type: replace-cross Abstract: Deep neural networks are increasingly applied in automated histopathology.
By Tarun Gogisetty, Naman Malpani, Gugan Thoppe, Sridharan Devarajan
AtlasPatch is a scalable, high‑throughput whole‑slide image preprocessing method that uses a foundation‑model‑based tissue detector operating at thumbnail resolution. By updating only 0.076% of the SAM2 model weights and leveraging a curated dataset of 30,000 thumbnail‑mask pairs, it generates accurate tissue masks and directly produces patch coordinates at the desired magnification, eliminating repeated patch‑level inference. The approach achieves 0.986 precision, is up to 16× faster than existing deep‑learning methods, and maintains downstream multiple‑instance learning performance across six slide‑level classification tasks.
By Ahmed Alagha, Christopher Leclerc, Yousef Kotp, Omar Metwally, Calvin Moras, Peter Rentopoulos, Ghodsiyeh Rostami, Bich Ngoc Nguyen, Jumanah Baig, Abdelhakim Khellaf, Vincent Quoc-Huy Trinh, Rabeb Mizouni, Hadi Otrok, Jamal Bentahar, Mahdi S. Hosseini
arXiv:2609.24116v1 Announce Type: new
Abstract: Although deep learning has advanced Whole Slide Image (WSI) Analysis, tissue artifacts like bubbles and folds often cause silent failures by concealing...
By Hyeseong Lee, Eunsu Kim, D M Bappy, Ho Heon Kim, Youngsuk Lee, Se Young Chun, Jang-Hwan Choi, Sung Hak Lee, Sangjeong Ahn
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat
arXiv:2609.18578v1 Announce Type: new
Abstract: Pathologists diagnose diseases by first locating suspicious tissue and then examining it at higher magnification, whereas self-supervised vision transf...
By Anabel Stammer, Valay Bundele, Mehran Hosseinzadeh, Hendrik P. A. Lensch
arXiv:2606. 06864v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become a standard paradigm for whole slide image (WSI) analysis in digital pathology, as it enables slide-level prediction without dense annotations.
By Yonghan Shin, Won-Ki Jeong
arXiv:2606. 17412v1 Announce Type: cross Abstract: Pathological images are inherently multi-scale, requiring pathologists to integrate evidence from global tissue architecture at low magnification to cellular morphology at higher magnification for accurate diagnosis.
By Chi Phan, Tianyi Zhang, Qiaochu Xue, Yufeng Wu, Dan Hu, Zeyu Liu, Sudong Wang, Yueming Jin
arXiv:2607. 13237v1 Announce Type: cross Abstract: Precise spatial-temporal annotation of laparoscopic videos is time-consuming and requires expert knowledge.
By Manasa Dendukuri, Matjaz Jogan, Daniel A. Hashimoto, Guiqiu Liao
arXiv:2609.36429v1 Announce Type: new
Abstract: Predicting gene expression from H&E-stained histology images offers a scalable alternative to costly spatial transcriptomics, yet most existing methods...
By Zijun Gao, Chunbin Gu, Jinxi Xiang, Xiangde Luo, Pheng-Ann Heng
arXiv:2609.00396v1 Announce Type: new
Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
By Chad Wong, Sicheng Chen, Tianyi Zhang, Enhui Chai, Yueming Jin, Zeyu Liu, Fei Xia