The study evaluates whether mammography foundation models, pretrained for breast cancer tasks, can predict 5‑year major adverse cardiovascular events (MACE) in women using only screening mammograms. In a cohort of 22,497 women (500 MACE events), the models achieved AUROCs of 0.823 and 0.822, outperforming an age‑only baseline. The models also identified higher risk in patients with radiologist‑documented breast arterial calcifications, despite never being trained on that label.
arXiv:2608.27690v1 Announce Type: cross Abstract: Cardiovascular risk prediction remains limited by incomplete clinical data and imaging biomarkers that reduce computed tomography (CT) to a small num...
The study audited ten different classifiers—including linear, tree‑ensemble, neural, glass‑box, and tabular foundation models—on national health survey data to predict myocardial infarction. By systematically removing features that could cause target leakage, the authors found that all models’ AUROC scores collapsed into a narrow band, indicating that reported high accuracy in prior work was largely due to leakage rather than model sophistication. The glass‑box explainable boosting machine performed comparably to other models while being much faster, and the authors demonstrated that fairness, calibration, and uncertainty can be audited and repaired without sacrificing performance.
The paper introduces SEM‑HD, a framework that leverages longitudinal mammography history as privileged information during training to improve risk prediction while requiring only a single current exam at inference. By having a student model predict latent representations of past visits and using teacher supervision from actual longitudinal data, SEM‑HD preserves temporal modeling benefits without needing prior exams at deployment. Experiments on three cohorts and two backbone architectures show consistent gains in long‑horizon AUC and pAUC, especially in low false‑positive‑rate regions, and recover much of the performance gap to full‑history models.
arXiv:2607. 10358v1 Announce Type: cross Abstract: Foundation models are increasingly used as image feature extractors for mammography, but their robustness under external domain shift remains unclear.
arXiv:2606. 10725v1 Announce Type: new Abstract: Background.
arXiv:2607. 11343v1 Announce Type: cross Abstract: Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection.
arXiv:2608. 10271v1 Announce Type: cross Abstract: Breast density classification is a critical component of breast cancer risk assessment, yet AI models often struggle to generalize across clinical sites due to vendor-specific acquisition styles.
A multicenter study developed an AI-enabled electrocardiography (AI-ECG) model that predicts vessel-specific hemodynamically significant stenosis using coronary computed tomographic angiography (CCTA) as the reference. The model demonstrated strong discrimination in internal and external cohorts, including normal ECGs, and produced low-, intermediate-, and high-risk strata that correlated with stenosis severity and major adverse cardiovascular events. Calibration, decision curve analyses, and integration with guideline-based pre-test probability showed clinical utility, while waveform and attribution analyses revealed physiologically meaningful ECG features linked to high-risk predictions.
Therapy-induced cardiotoxicity is the leading non-oncological cause of treatment interruption in breast cancer patients, yet early, automated risk stratification from routine cardiac imaging remains an unsolved problem. We present EchoRisk, the first curated, multicentre, longitudinal echocardiography dataset with explicit cardiotoxicity labels, released as the primary technical reference for the EchoRisk-MICCAI 2026 challenge.
arXiv:2607. 01039v1 Announce Type: cross Abstract: Therapy-induced cardiotoxicity is the leading non-oncological cause of treatment interruption in breast cancer patients, yet early, automated risk stratification from routine cardiac imaging remains an unsolved problem.
arXiv:2606. 28179v1 Announce Type: cross Abstract: Identifying robust associations between cardiac imaging phenotypes and clinical diseases is fundamental to population-scale cardiovascular research and reliable risk stratification.
arXiv:2608. 03079v1 Announce Type: cross Abstract: Breast core needle biopsy (CNB) is central to breast cancer diagnosis yet remains challenging because limited tissue sampling, lesion heterogeneity, and subtle morphologic overlap can obscure subtype distinctions.