arXiv:2607. 10358v1 Announce Type: cross Abstract: Foundation models are increasingly used as image feature extractors for mammography, but their robustness under external domain shift remains unclear.
arXiv:2608. 10271v1 Announce Type: cross Abstract: Breast density classification is a critical component of breast cancer risk assessment, yet AI models often struggle to generalize across clinical sites due to vendor-specific acquisition styles.
The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.
arXiv:2608. 09801v1 Announce Type: cross Abstract: Joint exam-level prediction and candidate-region localization may improve the usefulness of AI support in mammography.
DINO-Med introduces a patch‑based framework that adapts natural‑image foundation models, specifically DINOv3, to multi‑modal medical imaging. The method uses training‑free registration, automated localization, and mask‑filtered patch extraction to aggregate patch‑level features into subject‑level diagnostics. In liver fibrosis staging, DINOv3 outperforms handcrafted radiomics, ResNet, and SAM‑Med2D features, achieving 78.4% accuracy for mild fibrosis (S1) and 75.8% for cirrhosis (S4) on the CARE 2025 cohort.
arXiv:2608.21300v1 Announce Type: new Abstract: Foundation models for medical image segmentation, like prompt-based MedSAM, generalize well across domains and modalities, often in zero or few-shot se...
Deep learning-based computer-aided diagnosis (CAD) systems have shown strong performance in breast cancer diagnosis, particularly for classification tasks in mammography. However, domain shifts across multi-site datasets remain a challenge, especially when models are applied to unseen domains.
OncoVision is a privileged‑information training framework that learns from mammography images and clinical data during training but performs inference using only mammographic images. It employs an attention‑based encoder‑decoder to jointly segment masses, calcifications, axillary findings, and breast tissue, and predicts ten structured clinical features such as BI‑RADS. Two late‑fusion strategies (Independent and Dependent) integrate imaging, radiomic, and clinical information to improve diagnostic precision, and a retrospective multi‑reader study showed higher diagnostic confidence, reduced reading time, and segmentation accuracy comparable to or better than radiologists.
The paper introduces DINO-Med, a patch‑based framework that adapts natural‑image foundation models to multi‑modal medical imaging, specifically for liver fibrosis staging. It processes raw multimodal scans through training‑free registration, automated localization, and mask‑filtered patch extraction, then aggregates patch‑level insights into subject‑level diagnostics. Using the CARE 2025 Liver Track 4 cohort, the DINOv3‑based approach achieved the highest classification accuracy (78.4% for mild fibrosis and 75.8% for cirrhosis) compared to other feature representations.
arXiv:2608. 07749v1 Announce Type: cross Abstract: Parameter-efficient fine-tuning enables the adaptation of vision foundation models to biomedical tasks under limited computational resources, but a single low-rank update can constrain all task-specific changes to one narrow parameter subspace.
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
arXiv:2512. 17605v2 Announce Type: replace-cross Abstract: Robust mammography registration is essential for clinically relevant applications like tracking disease progression in breast tissue.
This study evaluates the classification accuracy of six modern deep‑learning architectures—VGG19, ResNet50, GoogleNet, ConvNeXt, EfficientNet, and Vision Transformers—on breast ultrasound images categorized by BI‑RADS. Using 2,945 training images and 936 validation images from 1,540 patients, the models were tested in full fine‑tuning, linear evaluation, and training‑from‑scratch settings. The best performance was achieved with full fine‑tuning, yielding 76.39 % accuracy and a 67.94 % F1 score.