arXiv Machine Learning

Longitudinal Risk Prediction in Mammography with Privileged History Distillation

The paper introduces SEM‑HD, a framework that leverages longitudinal mammography history as privileged information during training to improve risk prediction while requiring only a single current exam at inference. By having a student model predict latent representations of past visits and using teacher supervision from actual longitudinal data, SEM‑HD preserves temporal modeling benefits without needing prior exams at deployment. Experiments on three cohorts and two backbone architectures show consistent gains in long‑horizon AUC and pAUC, especially in low false‑positive‑rate regions, and recover much of the performance gap to full‑history models.

arXiv AI
Jul 14

Longitudinal Multi-View Breast Cancer Risk Prediction

arXiv:2607. 11343v1 Announce Type: cross Abstract: Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection.

By Solveig Thrun, Zijun Sun, Suaiba A. Salahuddin, Kristoffer Wickstr{\o}m, Elisabeth Wetzer, Stine Hansen, Robert Jenssen, Michael Kampffmeyer
arXiv Machine Learning
Aug 19

Mr.Dec: Daily-Scale Longitudinal Multimodal Modeling for 30-Day Readmission Prediction

Mr.Dec is a new Transformer‑decoder model that predicts 30‑day hospital readmission by treating each admission as a chronological sequence of daily multimodal events, integrating Electronic Health Record updates and Chest X‑ray findings. It uses disease‑specific supervised contrastive learning to shape a diagnosis‑aware latent space and preserves day‑level clinical signals that other methods often compress. Experiments on MIMIC‑IV and MIMIC‑CXR datasets show state‑of‑the‑art performance and the model can highlight "Critical Days" for actionable real‑time risk stratification.

By Minjun Kim, Jong Hak Moon
Hugging Face Trending Papers
Aug 13

Intervention-Aware Clinical World Model for Post-Op Outcome Forecasting in Cardiology

Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.

arXiv Machine Learning
2d ago

TALON: A Temporally Aware Longitudinal Framework for Radiology Report Generation

TALON is a Temporally Aware Longitudinal framework for radiology report generation that adaptively integrates variable‑length patient histories. Its Dual‑Channel Temporal Fusion Module compares each prior examination with the current one through similarity and change channels, using channel‑specific attention and a prior‑specific gate to weigh relevance and suppress redundancy. Experiments on MIMIC‑CXR demonstrate that TALON surpasses state‑of‑the‑art methods on clinical efficacy and graph‑based metrics, with performance improving as more prior examinations are available.

By Nien-Tsyr Sun, Min-Chen Chen, Hui Nien Hung, Vincent S. Tseng
arXiv Computer Vision
Sep 4

Solving the Needle-in-a-Haystack Problem in Mammography Vision-Language Model with Differentiable Subset Sampling

The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.

By Young Seok Jeon, Beatrice Brown-Mulry, Rohan Satya Isaac, Anjana Dissanayaka, Theo Dapamede, Mohammadreza Chavoshi, Judy Gichoya, Hari Trivedi
arXiv AI
2d ago

Diagnostic-Guided Longitudinal Modeling for Forecasting Retinal Atrophy Progression

The study proposes a diagnostic-guided approach to choose between stochastic and deterministic longitudinal imaging models based on whether inter-visit changes are driven by disease progression or acquisition variability. Applied to a large, heterogeneous Optos fundus autofluorescence archive, the diagnostic revealed weak time-dependent changes and limited benefit from stochastic models, leading to the development of the deterministic Temporal Retinal U‑Net (TRU). TRU outperformed other classical and deep‑learning comparators on image‑level and eye‑specific progression metrics across held‑out and independent zero‑shot transfer cohorts, though with slightly lower precision in a smaller cross‑vendor cohort.

By Liyin Chen, Souvick Mukherjee, Ines Maria De Carvalho Lains, Nazlee Zebardast, Mengyu Wang, Tobias Elze, Jason I. Comander
arXiv Machine Learning
5d ago

Mammography Foundation Models for Opportunistic Prediction of Major Adverse Cardiovascular Events

The study evaluates whether mammography foundation models, pretrained for breast cancer tasks, can predict 5‑year major adverse cardiovascular events (MACE) in women using only screening mammograms. In a cohort of 22,497 women (500 MACE events), the models achieved AUROCs of 0.823 and 0.822, outperforming an age‑only baseline. The models also identified higher risk in patients with radiologist‑documented breast arterial calcifications, despite never being trained on that label.

By Paula Feldman, Nusrat Binta Nizam, Sunwoo Kwak, Batuhan Karaman, Katerina Dodelzon, Mert Sabuncu