Longitudinal Multi-View Breast Cancer Risk Prediction
arXiv:2607. 11343v1 Announce Type: cross Abstract: Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection.
The paper introduces SEM‑HD, a framework that leverages longitudinal mammography history as privileged information during training to improve risk prediction while requiring only a single current exam at inference. By having a student model predict latent representations of past visits and using teacher supervision from actual longitudinal data, SEM‑HD preserves temporal modeling benefits without needing prior exams at deployment. Experiments on three cohorts and two backbone architectures show consistent gains in long‑horizon AUC and pAUC, especially in low false‑positive‑rate regions, and recover much of the performance gap to full‑history models.
arXiv:2607. 11343v1 Announce Type: cross Abstract: Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection.
arXiv:2608. 13518v1 Announce Type: new Abstract: Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint.
Mr.Dec is a new Transformer‑decoder model that predicts 30‑day hospital readmission by treating each admission as a chronological sequence of daily multimodal events, integrating Electronic Health Record updates and Chest X‑ray findings. It uses disease‑specific supervised contrastive learning to shape a diagnosis‑aware latent space and preserves day‑level clinical signals that other methods often compress. Experiments on MIMIC‑IV and MIMIC‑CXR datasets show state‑of‑the‑art performance and the model can highlight "Critical Days" for actionable real‑time risk stratification.
Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.
arXiv:2609.12834v1 Announce Type: new Abstract: Modelling how a disease progresses over time requires longitudinal imaging cohorts, which are scarce and small, whereas cross-sectional data -- one ima...
TALON is a Temporally Aware Longitudinal framework for radiology report generation that adaptively integrates variable‑length patient histories. Its Dual‑Channel Temporal Fusion Module compares each prior examination with the current one through similarity and change channels, using channel‑specific attention and a prior‑specific gate to weigh relevance and suppress redundancy. Experiments on MIMIC‑CXR demonstrate that TALON surpasses state‑of‑the‑art methods on clinical efficacy and graph‑based metrics, with performance improving as more prior examinations are available.
The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.
arXiv:2604. 26283v3 Announce Type: replace-cross Abstract: High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation.
arXiv:2606. 23487v2 Announce Type: replace Abstract: Medical vision-language models (VLMs) such as BiomedCLIP generalize broadly, but adapting them to a clinical service is as much a safety problem as an accuracy one.
The study proposes a diagnostic-guided approach to choose between stochastic and deterministic longitudinal imaging models based on whether inter-visit changes are driven by disease progression or acquisition variability. Applied to a large, heterogeneous Optos fundus autofluorescence archive, the diagnostic revealed weak time-dependent changes and limited benefit from stochastic models, leading to the development of the deterministic Temporal Retinal U‑Net (TRU). TRU outperformed other classical and deep‑learning comparators on image‑level and eye‑specific progression metrics across held‑out and independent zero‑shot transfer cohorts, though with slightly lower precision in a smaller cross‑vendor cohort.
The study evaluates whether mammography foundation models, pretrained for breast cancer tasks, can predict 5‑year major adverse cardiovascular events (MACE) in women using only screening mammograms. In a cohort of 22,497 women (500 MACE events), the models achieved AUROCs of 0.823 and 0.822, outperforming an age‑only baseline. The models also identified higher risk in patients with radiologist‑documented breast arterial calcifications, despite never being trained on that label.
arXiv:2605.28397v2 Announce Type: replace Abstract: Predicting which people with mild cognitive impairment will develop dementia matters for early treatment. Yet structural imaging models have relied...