arXiv Machine Learning

Longitudinal Risk Prediction in Mammography with Privileged History Distillation

The paper introduces SEM‑HD, a framework that leverages longitudinal mammography history as privileged information during training to improve risk prediction while requiring only a single current exam at inference. By having a student model predict latent representations of past visits and using teacher supervision from actual longitudinal data, SEM‑HD preserves temporal modeling benefits without needing prior exams at deployment. Experiments on three cohorts and two backbone architectures show consistent gains in long‑horizon AUC and pAUC, especially in low false‑positive‑rate regions, and recover much of the performance gap to full‑history models.

arXiv AI
Jul 14

Longitudinal Multi-View Breast Cancer Risk Prediction

arXiv:2607. 11343v1 Announce Type: cross Abstract: Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection.

By Solveig Thrun, Zijun Sun, Suaiba A. Salahuddin, Kristoffer Wickstr{\o}m, Elisabeth Wetzer, Stine Hansen, Robert Jenssen, Michael Kampffmeyer
arXiv Machine Learning
Sep 23

Foundation model embeddings capture pre-diagnostic changes on screening mammograms

The study examined whether embeddings from four foundation models—Mammo-CLIP, HOPPR, MedImageInsight, and BiomedCLIP—could detect pre‑diagnostic changes in screening mammograms. Using 1,773 biopsied women and matched controls, the researchers measured the speed of movement along a data‑derived “cancer direction” in embedding space over successive screening intervals. They found that embeddings from clinically grounded models (Mammo‑CLIP, HOPPR, MedImageInsight) showed faster drift in malignant cases compared to controls, while the general biomedical model BiomedCLIP did not, indicating that foundation model embeddings can encode early tissue changes without task‑specific fine‑tuning.

By Kalina P. Slavkova, Eric Brattain, Aditya Gowd, Akash Pattnaik, Jean-Benoit Delbrouck, Matthew Morgan, Julie Bauml, Javid Abderezaei, Khan Siddiqui
arXiv Machine Learning
Aug 19

Mr.Dec: Daily-Scale Longitudinal Multimodal Modeling for 30-Day Readmission Prediction

Mr.Dec is a new Transformer‑decoder model that predicts 30‑day hospital readmission by treating each admission as a chronological sequence of daily multimodal events, integrating Electronic Health Record updates and Chest X‑ray findings. It uses disease‑specific supervised contrastive learning to shape a diagnosis‑aware latent space and preserves day‑level clinical signals that other methods often compress. Experiments on MIMIC‑IV and MIMIC‑CXR datasets show state‑of‑the‑art performance and the model can highlight "Critical Days" for actionable real‑time risk stratification.

By Minjun Kim, Jong Hak Moon
Hugging Face Trending Papers
Aug 13

Intervention-Aware Clinical World Model for Post-Op Outcome Forecasting in Cardiology

Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.

arXiv Machine Learning
Sep 21

TALON: A Temporally Aware Longitudinal Framework for Radiology Report Generation

TALON is a Temporally Aware Longitudinal framework for radiology report generation that adaptively integrates variable‑length patient histories. Its Dual‑Channel Temporal Fusion Module compares each prior examination with the current one through similarity and change channels, using channel‑specific attention and a prior‑specific gate to weigh relevance and suppress redundancy. Experiments on MIMIC‑CXR demonstrate that TALON surpasses state‑of‑the‑art methods on clinical efficacy and graph‑based metrics, with performance improving as more prior examinations are available.

By Nien-Tsyr Sun, Min-Chen Chen, Hui Nien Hung, Vincent S. Tseng
arXiv Machine Learning
Oct 8

Patient, Place, Prior (P$^3$): What Counts as Personalization in Medical World Models?

The paper introduces Patient, Place, Prior (P³), an audit framework that evaluates whether a longitudinal medical imaging forecast benefits from a patient’s own imaging history (Patient), from patient‑matched spatial support (Place), and from predictive value beyond a population‑average model (Prior). It applies this framework to Cancer JEPA, a one‑step model that predicts future breast dynamic contrast‑enhanced MRI scans during neoadjuvant therapy, incorporating a lesion‑constrained neural correction trained with an occlusion‑based latent objective. Validation shows lower forecast error when the neural correction uses the patient’s own history and matched lesion maps, though the 95% interval comparing patient‑specific to population‑average corrections includes zero, illustrating that P³ distinguishes input usage from true patient‑specific predictive advantage.

By Xingrui Gu, Hanxue Gu, Yuxiang Zhang, Yang Yang