arXiv AI

Physics Informed Neural Network model for the dynamical study of Abdominal Aortic Aneurysm

arXiv Machine Learning
Aug 17

Learning Unsteady Aneurysm Hemodynamics with Physics-Informed DeepONets

arXiv:2608. 13629v1 Announce Type: cross Abstract: Clinically actionable, patient-specific hemodynamic assessment, specifically wall shear stress, vortex structure and pressure distributions, is critical for determining risky or unfavorable evolution in Abdominal Aortic Aneurysms (AAA).

By Oscar L. Cruz-Gonzalez, Val\'erie Deplano, Badih Ghattas
arXiv Machine Learning
Jun 5

Wall Shear Stress Reconstruction from Concentration: Differentiable Physics and Physics-Informed Neural Networks

arXiv:2606. 06313v1 Announce Type: cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients.

By Mahmoud Elhadidy, Siva Viknesh, Roshan M. D'Souza, Amirhossein Arzani
arXiv Machine Learning
Aug 12

Learning Disease-Sensitive Latent Interaction Graphs From Noisy Cardiac Flow Measurements

arXiv:2602. 23035v2 Announce Type: replace Abstract: Cardiac blood flow patterns contain rich information about disease severity and clinical interventions, yet current imaging and computational methods fail to capture underlying relational structures of coherent flow features.

By Viraj Patel, Marko Grujic, Philipp Aigner, Theodor Abart, Marcus Granegger, Deblina Bhattacharjee, Katharine Fraser
arXiv Machine Learning
4d ago

A Physics-Conditioned Neural Operator for Generalization of Atrioventricular Valve Mechanics across Pressure and Tissue Properties

The paper presents a Physics‑Conditioned Neural Operator (PCNO), a transformer‑based model that predicts mitral and tricuspid valve leaflet displacement, strain, and stress fields conditioned on systolic blood pressure and tissue properties. Trained on FEBio finite‑element simulations, PCNO achieves a displacement error of 4.48 % and maintains mean errors of unsupervised geometric measures within 3.5 % even when pressure and material parameters lie outside the training set, demonstrating a conditioned solution operator rather than simple interpolation. Compared to graph neural network baselines, PCNO shows superior accuracy, particularly in stress predictions.

By Shawn Koohy, Wensi Wu, Matthew A Jolley, Paris Perdikaris
arXiv AI
Aug 24

Anatomy-Informed Neural Networks: Encoding Anatomic Priors in Loss and Architecture, with an SE(3) Formulation of Guidewire-Induced Aortoiliac Deformation

The paper introduces Anatomy-Informed Neural Networks (AINN), which embed soft and hard anatomical priors into the loss function and network architecture to prevent anatomically impossible predictions. AINN is applied to a clinical scenario of aortoiliac deformation caused by a guidewire, modeling vessel and wire dynamics in SE(3) and training with a Wasserstein-2 loss from 2D angiograms. The study verifies the kinematics and loss against ground truth but does not yet train a network, outlining future work to apply the model to real CT data.

By David P. Stonko
arXiv AI
Sep 18

Physics-Informed Hemodynamic Modeling for Data-Free Prediction and Sparse-Data Assimilation

The paper introduces a physics-informed deep learning framework that reconstructs 3D coronary geometry from dual-view angiography and predicts velocity and pressure fields using a decoupled network with embedded physical priors. Across 32 patients and four flow conditions, the model achieved a trans‑stenotic pressure‑drop error of 2.02% and velocity/pressure relative‑L2 errors of 0.054 and 0.023, respectively, while matching hospital‑measured FFR with 93.8% diagnostic accuracy. The pipeline completes the full angiography‑to‑hemodynamics conversion in about 20 minutes per patient and supports sparse‑data assimilation for revascularization planning.

By Xi Chen, Jianchuan Yang, Hongde Li, Guangxin He, Qiuyu Ye, Qiang Luo, Mao Chen, Wenqi Hu
arXiv Computer Vision
Sep 7

Segmentation of the aorta in 4D flow MRI using 4D convolutional kernels and learning from sparse annotations

The study presents a fully automated 4D U‑Net that segments the ascending aorta, arch, and proximal descending aorta in 4D flow MRI using a hybrid 4D convolutional kernel and sparse 4D labels derived from 2D expert contours and centerlines. Trained on 268 scans from eight centers, the model achieved high Dice scores (0.927 internal, 0.911 external) and excellent agreement with expert measurements of peak velocity, net flow, wall shear stress, and diameters (ICC ≥0.954 internal, ≥0.980 external). Compared to frame‑wise 3D networks and semi‑automatic methods, the 4D U‑Net outperformed in diastole and generalised well to independent post‑contrast data.

By Hinrich Rahlfs, Julio Garcia, Chiara Manini, Markus H\"ullebrand, Sebastian Schmitter, Sarah Nordmeyer, Titus K\"uhne, Heiko Stern, Christian Meierhofer, Andreas Harloff, Sebastian Kelle, Alexander Lenz, Peter Bannas, Jeanette Schulz-Menger, Ralf F Trauzeddel, Anja Hennemuth