arXiv AI

Anatomy-Informed Neural Networks: Encoding Anatomic Priors in Loss and Architecture, with an SE(3) Formulation of Guidewire-Induced Aortoiliac Deformation

The paper introduces Anatomy-Informed Neural Networks (AINN), which embed soft and hard anatomical priors into the loss function and network architecture to prevent anatomically impossible predictions. AINN is applied to a clinical scenario of aortoiliac deformation caused by a guidewire, modeling vessel and wire dynamics in SE(3) and training with a Wasserstein-2 loss from 2D angiograms. The study verifies the kinematics and loss against ground truth but does not yet train a network, outlining future work to apply the model to real CT data.

arXiv Machine Learning
Aug 17

Learning Unsteady Aneurysm Hemodynamics with Physics-Informed DeepONets

arXiv:2608. 13629v1 Announce Type: cross Abstract: Clinically actionable, patient-specific hemodynamic assessment, specifically wall shear stress, vortex structure and pressure distributions, is critical for determining risky or unfavorable evolution in Abdominal Aortic Aneurysms (AAA).

By Oscar L. Cruz-Gonzalez, Val\'erie Deplano, Badih Ghattas
arXiv Machine Learning
Jun 5

Wall Shear Stress Reconstruction from Concentration: Differentiable Physics and Physics-Informed Neural Networks

arXiv:2606. 06313v1 Announce Type: cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients.

By Mahmoud Elhadidy, Siva Viknesh, Roshan M. D'Souza, Amirhossein Arzani
arXiv Computer Vision
Sep 7

Segmentation of the aorta in 4D flow MRI using 4D convolutional kernels and learning from sparse annotations

The study presents a fully automated 4D U‑Net that segments the ascending aorta, arch, and proximal descending aorta in 4D flow MRI using a hybrid 4D convolutional kernel and sparse 4D labels derived from 2D expert contours and centerlines. Trained on 268 scans from eight centers, the model achieved high Dice scores (0.927 internal, 0.911 external) and excellent agreement with expert measurements of peak velocity, net flow, wall shear stress, and diameters (ICC ≥0.954 internal, ≥0.980 external). Compared to frame‑wise 3D networks and semi‑automatic methods, the 4D U‑Net outperformed in diastole and generalised well to independent post‑contrast data.

By Hinrich Rahlfs, Julio Garcia, Chiara Manini, Markus H\"ullebrand, Sebastian Schmitter, Sarah Nordmeyer, Titus K\"uhne, Heiko Stern, Christian Meierhofer, Andreas Harloff, Sebastian Kelle, Alexander Lenz, Peter Bannas, Jeanette Schulz-Menger, Ralf F Trauzeddel, Anja Hennemuth
arXiv Machine Learning
Aug 4

MedSAM2-Anatomy: Training-Free Inference-Time Optimization for Musculoskeletal Segmentation

arXiv:2608. 00195v1 Announce Type: cross Abstract: High-resolution 3D segmentation of hip and shoulder anatomy from CT and MRI is essential for surgical planning, yet frozen segmentation models often fail under domain shift.

By John Garcia Henao, Nicholas B\"unger, Benedikt Herzog, Cindy Guerrero Toro, Benjamin Vella, Matthias Biner, Rico Br\"utsch, Carmen Castroviejo Fernandez, Felix \"Ottl, Norman Juchler, Armando Hoch, Bettina Hochreiter, Sven Hirsch, Sebastiano Caprara
arXiv Machine Learning
Sep 2

LLM-driven design of physics-constrained constitutive models: two agents are better than one

The paper presents a novel multi‑agent approach to generating physics‑constrained constitutive models using large language models (LLMs). A Creator agent proposes a model tailored to the data, while an Inspector agent audits each proposal against nine physical constraints and requests refinement if violations occur. Experiments with constitutive artificial neural networks on brain tissue, rubber, and porcine skin show that adding the Inspector increases the proportion of models passing all checks from 90 % to 95 % for Claude Opus 4.7 and from 47 % to 60 % for Kimi K2.5, while the resulting models match or exceed expert‑designed models in accuracy and generalization.

By Marius Tacke, Matthias Busch, Kian Abdolazizi, Jonas Eichinger, Kevin Linka, Roland Aydin, Christian Cyron
arXiv Machine Learning
Aug 12

Learning Disease-Sensitive Latent Interaction Graphs From Noisy Cardiac Flow Measurements

arXiv:2602. 23035v2 Announce Type: replace Abstract: Cardiac blood flow patterns contain rich information about disease severity and clinical interventions, yet current imaging and computational methods fail to capture underlying relational structures of coherent flow features.

By Viraj Patel, Marko Grujic, Philipp Aigner, Theodor Abart, Marcus Granegger, Deblina Bhattacharjee, Katharine Fraser
arXiv Machine Learning
Sep 21

Reconstruction of 4D Mitral Regurgitation Hemodynamics from Sparse Planar Data using Deep Operator Networks with Test-Time Adaptation

The paper presents a Deep Operator Network that reconstructs full‑field 4D mitral regurgitation hemodynamics from sparse planar velocity data and boundary pressure traces. The network is pretrained on a URANS database of eleven orifice phantoms and then fine‑tuned on new cases, achieving rapid predictions in minutes. While the adaptation improves flow topology in the observed plane, reconstruction error increases sharply with distance from that plane, limiting physical consistency in the surrounding volume.

By Jakob Marcel Hoffmann, Yosuke Hasegawa, Alexander Stroh
Hugging Face Trending Papers
Jul 28

Where Physics Meets Privacy: Federated PINNs for Privacy-Preserving Brain Tumor Biomechanical Modeling

Brain tumors such as glioma, meningioma, and pituitary adenoma alter the mechanical behavior of soft brain tissue, yet common diagnostic methods rely on static imaging that cannot capture tumor growth, tissue displacement, or changes in stiffness over time. Deep learning models for this task typically require pooling patient data at one site, which conflicts with privacy rules such as GDPR and HIPAA and limits generalization across institutions, a challenge that is pronounced in neuro oncology given patient diversity.