The paper introduces a physics-informed deep learning framework that reconstructs 3D coronary geometry from dual-view angiography and predicts velocity and pressure fields using a decoupled network with embedded physical priors. Across 32 patients and four flow conditions, the model achieved a trans‑stenotic pressure‑drop error of 2.02% and velocity/pressure relative‑L2 errors of 0.054 and 0.023, respectively, while matching hospital‑measured FFR with 93.8% diagnostic accuracy. The pipeline completes the full angiography‑to‑hemodynamics conversion in about 20 minutes per patient and supports sparse‑data assimilation for revascularization planning.
By Xi Chen, Jianchuan Yang, Hongde Li, Guangxin He, Qiuyu Ye, Qiang Luo, Mao Chen, Wenqi Hu
arXiv:2609.15104v1 Announce Type: cross
Abstract: We present the development and application of a three-dimensional Physics-Informed Neural Network (PINN) framework for the investigation of haemodyna...
By Adri\'an Robles Arques, Mart\'in Ruiz Fernandez, Javier Sanchis, Miguel A. Teruel, Juan Trujillo
arXiv:2606. 06313v1 Announce Type: cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients.
By Mahmoud Elhadidy, Siva Viknesh, Roshan M. D'Souza, Amirhossein Arzani
arXiv:2605. 08832v3 Announce Type: replace Abstract: Neural surrogate models for computational fluid dynamics (CFD) are typically trained as forward operators that map explicit problem specifications, such as geometry and boundary conditions, to solution fields.
By Jonas Weidner, Yeray Martin-Ruisanchez, Daniel Rueckert, Benedikt Wiestler, Julian Suk
arXiv:2602. 23035v2 Announce Type: replace Abstract: Cardiac blood flow patterns contain rich information about disease severity and clinical interventions, yet current imaging and computational methods fail to capture underlying relational structures of coherent flow features.
By Viraj Patel, Marko Grujic, Philipp Aigner, Theodor Abart, Marcus Granegger, Deblina Bhattacharjee, Katharine Fraser
The paper presents a Deep Operator Network that reconstructs full‑field 4D mitral regurgitation hemodynamics from sparse planar velocity data and boundary pressure traces. The network is pretrained on a URANS database of eleven orifice phantoms and then fine‑tuned on new cases, achieving rapid predictions in minutes. While the adaptation improves flow topology in the observed plane, reconstruction error increases sharply with distance from that plane, limiting physical consistency in the surrounding volume.
By Jakob Marcel Hoffmann, Yosuke Hasegawa, Alexander Stroh