arXiv Machine Learning
Aug 31

Destroy Me: Automatic Artifact Generation for Histopathology Images

The paper introduces "Destroy Me", a hybrid framework that generates realistic histopathology artifacts using Stable Diffusion and physics‑based modeling to create six common artifact types. Artifact realism is evaluated with KID and color Wasserstein metrics, and models trained on these augmented images outperform baselines on lung adenocarcinoma classification, achieving a 10.5% relative boost in macro F1‑score and a 15% increase in Cohen’s Kappa. The study highlights that selective, impact‑weighted augmentation is essential for enhancing robustness while preserving subtle diagnostic features.

By Zuzanna Krawczyk-Borysiak, Adam Krawczyk, Mateusz Miller, Gabriela Kaczmarek, S{\l}awomir Paku{\l}o, Ma{\l}gorzata Sok\'o{\l}, \.Zaneta Swiderska-Chadaj
arXiv Computer Vision
Sep 3

AtlasPatch: Scalable Foundation Model-based Tissue Detection and Patch Extraction for Computational Pathology

AtlasPatch is a scalable, high‑throughput whole‑slide image preprocessing method that uses a foundation‑model‑based tissue detector operating at thumbnail resolution. By updating only 0.076% of the SAM2 model weights and leveraging a curated dataset of 30,000 thumbnail‑mask pairs, it generates accurate tissue masks and directly produces patch coordinates at the desired magnification, eliminating repeated patch‑level inference. The approach achieves 0.986 precision, is up to 16× faster than existing deep‑learning methods, and maintains downstream multiple‑instance learning performance across six slide‑level classification tasks.

By Ahmed Alagha, Christopher Leclerc, Yousef Kotp, Omar Metwally, Calvin Moras, Peter Rentopoulos, Ghodsiyeh Rostami, Bich Ngoc Nguyen, Jumanah Baig, Abdelhakim Khellaf, Vincent Quoc-Huy Trinh, Rabeb Mizouni, Hadi Otrok, Jamal Bentahar, Mahdi S. Hosseini
arXiv Computer Vision
Aug 25

LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis

LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.

By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
arXiv AI
Jun 8

DaX: Learning General Pathology Representations Across Scales

arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.

By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
arXiv AI
Jul 31

PatchDenoiser: Parameter-efficient multi-scale patch learning and fusion denoiser for Low-dose CT imaging

arXiv:2602. 21987v3 Announce Type: replace-cross Abstract: Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or scanner limitations, affecting both clinical interpretation and downstream analysis.

By Jitindra Fartiyal, Pedro Freire, Sergei K. Turitsyn, Sergei G. Solovski