arXiv:2609.24725v1 Announce Type: cross Abstract: Head-and-neck anatomy changes over a six-to-seven-week proton course, and the anatomy of a later week cannot be imaged when the plan is made. We pres...
The paper introduces DAMM‑Net++, a 2.5D neural network for thoracic organ‑at‑risk and target volume segmentation that tackles inter‑slice surface incoherence, small low‑contrast target failure, and lack of per‑case reliability signals. Its core is an anatomy‑change‑aware bidirectional selective state‑space memory that propagates context across axial slices, complemented by a boundary‑aware decoder and an uncertainty head for calibrated per‑voxel confidence. Evaluations on 2,146 patients, an external cohort, and a reader study show high Dice scores (0.955), low HD95 (3.78 mm), significant time savings (75‑80 %) for clinicians, and improved junior‑reader performance, with the system fully integrated into a clinical workflow.
arXiv:2607. 11949v1 Announce Type: cross Abstract: We present a clinically deployed end-to-end auto-contouring system for cervical cancer radiotherapy planning, anchored by the Boundary-Aware Transformer with Region-Aware Mamba (BAT-RM), a hybrid architecture that integrates Sobel-gated boundary attention, a linear-time, multi-directional Mamba module for long-range context, and a boundary-skeleton-guided fusion gate.
arXiv:2509. 21913v2 Announce Type: replace-cross Abstract: Background: Cone-beam computed tomography CBCT is a commonly used modality for image guided radiotherapy.
The paper introduces SWIFT, a Swin V2‑based model pretrained on 10,444 3D CT volumes and fine‑tuned for rectal cancer segmentation on T2‑weighted MRI. Four configurations—full fine‑tuning (SWIFT), decoder compression (SWIFTe), low‑rank adaptation (SWIFTe‑LoRA), and a LoRA‑decoder ensemble (SWIFTe‑LDE4)—were evaluated on 247 cases, showing that SWIFTe reduces parameters by 70.1% while improving tumor detection and radiomic agreement. The study also demonstrates a trade‑off between detection and boundary agreement, and highlights that SWIFTe‑LDE4 achieves the lowest calibration errors after temperature scaling.
CATCH is a conditional 3D diffusion model operating in an invertible Haar-wavelet domain designed to inpaint masked regions in T1‑weighted brain MRI with plausible, tumor‑free tissue while preserving observed anatomy. The model’s denoiser uses noisy target coefficients, voided‑image coefficients, and a signed mask, guided by tumor‑excluded wavelet reconstruction and a hole‑focused loss, and hard compositing ensures observed voxels remain unchanged. Experiments on BraTS data show that a weighted mixture of tumor‑derived, irregular‑blob, and ellipsoidal masks yields the best performance, achieving higher SSIM, PSNR, and lower MSE compared to fixed or random augmentation baselines.
arXiv:2608.28705v1 Announce Type: cross Abstract: Dose accumulation is increasingly important in adaptive radiation therapy and reirradiation, but its clinical validity depends on the performance of...
arXiv:2609.13838v1 Announce Type: new Abstract: Purpose: To develop and evaluate TotalSynth, a reusable pretrained framework for whole-body synthetic CT (sCT) generation from MRI and cone-beam CT (CB...
The paper introduces Observation‑Anchored Selective Assimilation (OASA) for forecasting tumor‑state proxies in post‑treatment glioma patients using serial MRI observations. OASA anchors the patient‑specific state with an intermediate observation and selectively updates it via a tiered rule and voxel‑wise soft gate, outperforming baseline methods in Dice score at certain thresholds. The approach is validated on 120 patient triplets and the code is publicly released.
arXiv:2608.29348v1 Announce Type: new Abstract: Background: Patient details and acquisition metadata are important for clinical decisions, image quality control, and automated research pipelines, but...
An integrated, web‑based platform has been developed to process diffusion‑weighted imaging (DWI) from MR‑guided linear accelerators and provide structured, literature‑grounded clinical interpretations. The system combines a deep‑learning pipeline for distortion correction, denoising, and IVIM/ADC fitting with a retrieval‑augmented generation (RAG) agent that references a curated knowledge base and traces each statement to its source. Independent expert ratings of nine glioblastoma cases showed high scores for clinical reasoning, citation quality, and overall utility, with a mean rating of 4.65 out of 5.
arXiv:2605.20470v2 Announce Type: replace-cross Abstract: Cone-beam CT (CBCT) is routinely acquired during radiotherapy for patient setup, but its quantitative reliability is degraded by scatter, noi...