arXiv AI

EPC-RawDC: Equivariant Physics Constrained 3D Diffusion with Raw Data Consistency for CBCT to CT Image Synthesis

EPC‑RawDC is a 3‑D latent diffusion model that synthesises CT images from CBCT scans by enforcing two physics‑based constraints: a geometry‑equivariant projection loss and raw data consistency using scan‑specific CBCT projections. Trained on two clinical cohorts with different scanner geometries, the method achieved SSIM of 0.97 and improved PSNR and MAE over a baseline DDPM, reducing projection and equivariant errors by 55 % and 41 % respectively.

arXiv AI
3d ago

EUReCA: End-to-End Unified CBCT Reconstruction Across Clinical Acquisitions

EUReCA is a geometry‑aware, feed‑forward model that reconstructs cone‑beam CT images from 8–100 projections without needing view‑specific retraining. It encodes each projection with a shared multiscale backbone, back‑projects features into 3‑D grids, aggregates variable views at fixed cost, and refines the volume using a global transformer and decoder. On simulated and real patient data, EUReCA outperforms existing feed‑forward and iterative methods, achieving high PSNR and superior performance across all tested view counts.

By Jiening Zhu, Chengzhu Zhang, Jason Fan, LiCheng Kuo, Weixing Cai, Xiuxiu He, Laura Cervino, Jean Moran, Xiang Li, Tianfang Li, Yabo Fu
arXiv AI
Aug 11

Toward CT-Equivalent Image Quality in Low-Dose Radiotherapy Planning: Conditional Diffusion-Based CBCT-to-CT Synthesis and the Impact of CBCT Input Representation

arXiv:2608. 08919v1 Announce Type: cross Abstract: During standard radiotherapy planning, repeated CT acquisitions are often required for patient registration, verification, and adaptive planning, resulting in increased cumulative X-ray dose.

By Alzahra Altalib, Chunhui Li, Christopher Hamill Taylor, Sankar Pillai, Alessandro Perelli
arXiv AI
Sep 17

Dose-Aware Cold Diffusion with Physics Consistency for Generalizable Low-Dose CT Reconstruction

The paper introduces Dose-Aware Cold Diffusion (DACD), a physics-consistent framework that treats radiation dose as a continuous latent variable in a cold diffusion process for low-dose CT reconstruction. DACD combines dose-aware perception, multi-scale structural priors, and dose-calibrated step allocation to guide denoising, and adds an iterative forward-backprojection correction to enforce projection-domain consistency. Experiments on Mayo-2020, Mayo-2016, and LoDoPaB-CT show DACD outperforms existing diffusion-based and physics-guided methods, especially at ultra-low doses, and generalizes robustly across continuous, unseen dose levels.

By Md Imam Ahasan, Guangchao Yang, A F M Abdun Noor, S M Hasan Mahmud, Md Mahfuzur Rahman
arXiv Machine Learning
Aug 5

Dual-domain U-Nets with embedded back projection operators for motion-resolved 4D CBCT reconstruction

arXiv:2608. 03430v1 Announce Type: cross Abstract: Four-dimensional cone beam CT (4D CBCT) is important for image-guided radiation therapy of thoracic cancers, but its use is limited by long scan times, causing high patient dose and motion/sparse-sampling artifacts.

By Ivo Herzig, Pascal Paysan, Daniel Barco, Marc Andr\'e Stadelmann, Frank-Peter Schilling, Igor Peterlik, Michal Walczak, Lijin Aryananda, Woo Sang Ahn, Rudolf Marcel F\"uchslin, Lukas Lichtensteiger
arXiv Machine Learning
Sep 3

Conditional Diffusion Posterior Alignment for Sparse-View CT Reconstruction

The paper introduces Conditional Diffusion Posterior Alignment (CDPA), a method that scales diffusion-based sparse‑view CT reconstruction to large 3D volumes by conditioning a 2D U‑Net diffusion model on an initial 3D reconstruction and enforcing data‑consistency alignment. CDPA addresses high memory demands, limited 3D training data, and slice‑wise inconsistencies, achieving state‑of‑the‑art performance on synthetic and real Cone Beam CT data. The authors also demonstrate that the same approach improves fast denoising U‑Nets, delivering near‑diffusion quality at a fraction of the computational cost.

By Luis Barba, Johannes Kirschner, Benjamin Bejar
arXiv Machine Learning
Jul 15

GenDiff: A Dose and Anatomy Aware Diffusion Model with Structural Prior Refinement for Low-Dose CT Reconstruction and Generalization

arXiv:2607. 11941v1 Announce Type: cross Abstract: Computed tomography (CT) is a critical imaging modality for clinical diagnosis, but reducing radiation dose inevitably introduces severe noise and structured artifacts that degrade image quality.

By Md Imam Ahasan, Guangchao Yang, A F M Abdun Noor, Kah Ong Michael Goh, S. M. Hasan Mahmud, Md Mahfuzur Rahman
arXiv Computer Vision
Sep 16

Efficient 3D Whole-Body PET Image Denoising via Conditional Rectified Flow With Optimized Sampling Strategy

The paper introduces a one‑pass conditional 3D rectified flow (3D Flow) framework for denoising whole‑body PET images, employing an optimized non‑uniform sampling strategy and a linear‑interpolant velocity‑matching objective. It reconstructs a full 3D volume in about 30 seconds, dramatically faster than multi‑hour 3D diffusion models, while maintaining high global image quality and lesion conspicuity even at ultra‑low doses (down to 1/100 of standard). Zero‑shot transfer tests on independent clinical data demonstrate robust performance across datasets and unseen dose levels.

By Jiale Shen, Guolin Wang, Chenhao Wang, Xinhui Su, Wei Luo, Feng Yu
arXiv AI
Sep 24

Field-of-View Extension in Dental Cone-Beam CT via Implicit Neural Representations and Diffusion Model-Based Refinement

The paper presents a three‑stage framework to extend the field of view in dental cone‑beam CT scans that are limited by truncated detector configurations. First, an implicit neural representation estimates missing projection data; second, an iterative reconstruction generates a secondary volumetric image with better anatomical consistency; third, a fast diffusion model refines the image for enhanced quality. Experiments show reduced truncation artifacts and improved reconstruction of structures beyond the original field of view.

By Susanne Schaub, Florentin Bieder, Matheus L. Oliveira, Yulan Wang, Buyanbileg Sodnom-ish, Dorothea Dagassan-Berndt, Michael M. Bornstein, Philippe C. Cattin