arXiv Machine Learning

Observation-Anchored Selective Assimilation for Longitudinal Tumor-State Proxy Forecasting in Post-Treatment Glioma

The paper introduces Observation‑Anchored Selective Assimilation (OASA) for forecasting tumor‑state proxies in post‑treatment glioma patients using serial MRI observations. OASA anchors the patient‑specific state with an intermediate observation and selectively updates it via a tiered rule and voxel‑wise soft gate, outperforming baseline methods in Dice score at certain thresholds. The approach is validated on 120 patient triplets and the code is publicly released.

Hugging Face Trending Papers
Aug 18

CFB-GBM v2.0: An Augmented Longitudinal Dataset for Multi-Modal Glioblastoma Segmentation, Radiomics, and RANO Progression Tracking

CFB-GBM v2.0 is an expanded longitudinal dataset of 264 glioblastoma patients, providing complete Gross Tumour Volume (GTV) delineations across all timepoints and derived volumetric RANO 2.0 response labels. The dataset includes brain masks, pre‑computed radiomic features, and WHO classification guidelines, all validated by radiation oncologists. It is publicly available on TCIA for use in computational methods for treatment response prediction and disease progression modeling.

arXiv AI
Sep 25

CATCH: Counterfactual Anatomical Tissue Inpainting with Conditional Haar Diffusion

CATCH is a conditional 3D diffusion model operating in an invertible Haar-wavelet domain designed to inpaint masked regions in T1‑weighted brain MRI with plausible, tumor‑free tissue while preserving observed anatomy. The model’s denoiser uses noisy target coefficients, voided‑image coefficients, and a signed mask, guided by tumor‑excluded wavelet reconstruction and a hole‑focused loss, and hard compositing ensures observed voxels remain unchanged. Experiments on BraTS data show that a weighted mixture of tumor‑derived, irregular‑blob, and ellipsoidal masks yields the best performance, achieving higher SSIM, PSNR, and lower MSE compared to fixed or random augmentation baselines.

By Simon Winther Albertsen, Hjalte Bjoernstrup, Said Djafar Said, Mostafa Mehdipour Ghazi
arXiv Computer Vision
Aug 28

Parameter-Efficient pretrained-CT-to-MRI Transfer for Rectal Cancer Segmentation: Performance-Calibration Trade-offs

The paper introduces SWIFT, a Swin V2‑based model pretrained on 10,444 3D CT volumes and fine‑tuned for rectal cancer segmentation on T2‑weighted MRI. Four configurations—full fine‑tuning (SWIFT), decoder compression (SWIFTe), low‑rank adaptation (SWIFTe‑LoRA), and a LoRA‑decoder ensemble (SWIFTe‑LDE4)—were evaluated on 247 cases, showing that SWIFTe reduces parameters by 70.1% while improving tumor detection and radiomic agreement. The study also demonstrates a trade‑off between detection and boundary agreement, and highlights that SWIFTe‑LDE4 achieves the lowest calibration errors after temperature scaling.

By Aneesh Rangnekar, Jorge Tapias Gomez, Joseph O Deasy, Harini Veeraraghavan
arXiv Computer Vision
Sep 3

The Diagnosis a Reporter Leaves Unspoken: Surfacing Frozen Tumor Features for Brain-Tumor MRI Reporting

The paper introduces NeuroFusion, an assistive brain‑MRI report generator that surfaces latent tumor signals from a frozen Mistral‑7B backbone. By adding discriminative field‑classifier heads over per‑lesion features, NeuroFusion restores accurate diagnoses (meningioma 0.92, metastasis 0.75) and improves prose quality while reducing latency 5–6×. A controlled negative result shows that overriding the decoder with a learned diagnosis pin harms performance, and grammar‑constrained decoding yields high schema‑validity (92.3%).

By Khawaja Murad ul Hassan, Ruqiyya Adil, Adil Qayyum, Rida Hassan, Asad Mansoor Khan, Muhammad Usman Akram, Mehran Ebrahimi
arXiv Computer Vision
Sep 11

Pre- and Post-Treatment Brain Metastases Segmentation Using nnU-Net with Post-Processing for BraTS 2026

The paper presents a segmentation pipeline for brain metastases in both pre‑ and post‑treatment cases using a 5‑fold nnU‑Net ResEnc‑L ensemble trained on 1,296 four‑modality cases. A rule‑based post‑processing cascade improves the lesion‑wise Dice similarity coefficient (LW‑DSC) for enhancing tumour, tumour core, whole tumour, and resection cavity sub‑regions, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 respectively on the official validation leaderboard. The authors conduct a five‑fold out‑of‑fold analysis to validate the robustness of each post‑processing stage, provide a mechanistic explanation of LW‑DSC behaviour, and report thirteen negative results that challenge common intuitions, with all code released under Apache‑2.0.

By Haobin Liu, Xin Wang
Hugging Face Trending Papers
Sep 10

Pre- and Post-Treatment Brain Metastases Segmentation Using nnU-Net with Post-Processing for BraTS 2026

The paper presents a pragmatic segmentation pipeline for brain metastases in the BraTS 2026 Task 1, using a 5‑fold nnU-Net ResEnc‑L ensemble trained for 1,000 epochs on 1,296 four‑modality cases. A rule‑based post‑processing cascade tuned for the lesion‑wise Dice similarity coefficient (LW‑DSC) improves performance, achieving LW‑DSC scores of 0.733, 0.751, 0.713, and 0.549 on enhancing tumour, tumour core, whole tumour, and resection cavity, respectively. The authors audit each post‑processing stage with a five‑fold out‑of‑fold analysis, confirm two stages as robust, and provide a mechanistic analysis of LW‑DSC, along with thirteen negative results that challenge common intuitions.