arXiv Computer Vision

Anatomy-Change-Aware Bidirectional Selective State-Space Memory for Clinically Deployed Thoracic Radiotherapy Auto-Contouring

The paper introduces DAMM‑Net++, a 2.5D neural network for thoracic organ‑at‑risk and target volume segmentation that tackles inter‑slice surface incoherence, small low‑contrast target failure, and lack of per‑case reliability signals. Its core is an anatomy‑change‑aware bidirectional selective state‑space memory that propagates context across axial slices, complemented by a boundary‑aware decoder and an uncertainty head for calibrated per‑voxel confidence. Evaluations on 2,146 patients, an external cohort, and a reader study show high Dice scores (0.955), low HD95 (3.78 mm), significant time savings (75‑80 %) for clinicians, and improved junior‑reader performance, with the system fully integrated into a clinical workflow.

arXiv AI
Jul 15

BAT-RM: A Boundary-Aware Transformer with Region-Aware Multi-Directional Mamba for Clinically Deployed Cervical Cancer Radiotherapy Auto-Contouring

arXiv:2607. 11949v1 Announce Type: cross Abstract: We present a clinically deployed end-to-end auto-contouring system for cervical cancer radiotherapy planning, anchored by the Boundary-Aware Transformer with Region-Aware Mamba (BAT-RM), a hybrid architecture that integrates Sobel-gated boundary attention, a linear-time, multi-directional Mamba module for long-range context, and a boundary-skeleton-guided fusion gate.

By Istiak Ahmed, Kazi Shahriar Sanjid, Galib Ahmed, Md. Tanzim Hossain, Md. Anwarul Islam, Shahrukh Khan, Md. Ashrif Rahman Arian, Md. Nishan Khan, Md. Misbah Khan, S M Hasibul Hoque, Rahnuma Shahrin Rista, Md. Jobairul Islam, Sheikh Anisul Haque, Md Arifur Rahman, Syed Md. Akram Hussain, Syeda Nashra, Sayeed Shafayet Chowdhury, Md. Mostafa Kamal Sarker, M. Monir Uddin
arXiv AI
Aug 13

A Neighborhood Attention Transformer Network for Enhanced 3D Segmentation of the Left Anterior Descending Artery

arXiv:2608. 12274v1 Announce Type: cross Abstract: Background: Accurate segmentation of the Left Anterior Descending (LAD) artery in 3D free-breathing, non-contrast CT is critical for cardiac dose sparing in thoracic radiotherapy.

By Rafi Ibn Sultan, Chengyin Li, Yiannos Demetriou, Ahmed I. Ghanem, Joshua P. Kim, Justine Cunningham, Hassan Bagher-Ebadian, Dongxiao Zhu, Kundan S. Thind
arXiv Computer Vision
Sep 4

Improving Clinical Target Volume Segmentation Accuracy using Anatomical Priors and Active Learning for the AGITG TOPGEAR Clinical Trial

The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.

By Phillip Chlap, Mark Lee, Trevor Leong, Matthew Field, Jason Dowling, Hang Min, Julie Chu, Jennifer Tan, Phillip K. Tran, Tomas Kron, Annette Haworth, Martin A. Ebert, Shalini K. Vinod, Lois Holloway
arXiv Computer Vision
Aug 28

DALE-CT: Depth-Aware 2D Slice Encoders Learn an Anatomical World Model of Chest CT

DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.

By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner
arXiv AI
1d ago

An Uncertainty-Guided Digital Twin Framework for Online Adaptive Proton Therapy in Head and Neck Cancer: A Feasibility Study

arXiv:2609.39010v1 Announce Type: cross Abstract: Objective: Head and neck (HN) proton therapy spans six to seven weeks of anatomical change, while offline replanning takes about a week. We present a...

By Yizhou Wu, Ryan J. Sanford, Huiqiao Xie, Jie Ding, Shupeng Chen, Tung-Ho Wu, Ping-Hsiu Wu, Justin Roper, Jun Zhou, Minglei Kang, Bill Stokes, Sibo Tian, David S. Yu, Xiaofeng Yang, Chih-Wei Chang