The paper introduces SWIFT, a Swin V2‑based model pretrained on 10,444 3D CT volumes and fine‑tuned for rectal cancer segmentation on T2‑weighted MRI. Four configurations—full fine‑tuning (SWIFT), decoder compression (SWIFTe), low‑rank adaptation (SWIFTe‑LoRA), and a LoRA‑decoder ensemble (SWIFTe‑LDE4)—were evaluated on 247 cases, showing that SWIFTe reduces parameters by 70.1% while improving tumor detection and radiomic agreement. The study also demonstrates a trade‑off between detection and boundary agreement, and highlights that SWIFTe‑LDE4 achieves the lowest calibration errors after temperature scaling.
By Aneesh Rangnekar, Jorge Tapias Gomez, Joseph O Deasy, Harini Veeraraghavan
arXiv:2609.24769v1 Announce Type: new
Abstract: Brain metastases are the most common intracranial malignancy, occurring in roughly 30% of patients with primary solid tumors and carrying a median surv...
By Mahdi Islam, Musarrat Tabassum
The paper introduces DAMM‑Net++, a 2.5D neural network for thoracic organ‑at‑risk and target volume segmentation that tackles inter‑slice surface incoherence, small low‑contrast target failure, and lack of per‑case reliability signals. Its core is an anatomy‑change‑aware bidirectional selective state‑space memory that propagates context across axial slices, complemented by a boundary‑aware decoder and an uncertainty head for calibrated per‑voxel confidence. Evaluations on 2,146 patients, an external cohort, and a reader study show high Dice scores (0.955), low HD95 (3.78 mm), significant time savings (75‑80 %) for clinicians, and improved junior‑reader performance, with the system fully integrated into a clinical workflow.
By Galib Ahmed, Istiak Ahmed, Aritra Islam Saswato, Asib Mostakim Fony, Kazi Shahriar Sanjid, Md. Tanzim Hossain, Md. Anwarul Islam, Md. Nishan Khan, Md. Misbah Khan, Labiba Faiza Karim, Jobaer Rahman, S M Hasibul Hoque, Rahnuma Shahrin Rista, Kamruzzaman Rumman, Md Arifur Rahman, Syed Md. Akram Hussain, Mohammad Ashrafuzzaman Khan, M. Monir Uddin
The study introduces a voxel-spacing-aware radiomic framework that incorporates physical geometry into texture computation without resampling, modifying PyRadiomics to preserve native image signals. Four extraction configurations—native non-resampled (NR), isotropic resampling (RS), voxel-spacing-aware (VS), and fake-isotropic preprocessing (FK)—were compared across 685 CT pulmonary nodules and 209 MRI breast cases, evaluating 196 radiomic descriptors. Results show that VS closely matches NR (median ICC(A,1) ≈0.998) while RS and FK exhibit lower agreement, indicating that spacing metadata alone can significantly influence radiomic features.
By David Corral Fontecha, Juan Miranda Bautista, Pablo Menendez Fern\'andez-Miranda, Sergio Rubio-Mart\'in, Lara Lloret Iglesias, Jose A. Vega
arXiv:2608.28773v1 Announce Type: cross
Abstract: Perceptual losses are widely used in medical image synthesis because they encourage agreement in high-level structure beyond voxel-wise intensity sim...
By Changsheng Fang, Dayang Wang, T. Campbell Arnold, Enhao Gong, Srivathsa Pasumarthi
CATCH is a conditional 3D diffusion model operating in an invertible Haar-wavelet domain designed to inpaint masked regions in T1‑weighted brain MRI with plausible, tumor‑free tissue while preserving observed anatomy. The model’s denoiser uses noisy target coefficients, voided‑image coefficients, and a signed mask, guided by tumor‑excluded wavelet reconstruction and a hole‑focused loss, and hard compositing ensures observed voxels remain unchanged. Experiments on BraTS data show that a weighted mixture of tumor‑derived, irregular‑blob, and ellipsoidal masks yields the best performance, achieving higher SSIM, PSNR, and lower MSE compared to fixed or random augmentation baselines.
By Simon Winther Albertsen, Hjalte Bjoernstrup, Said Djafar Said, Mostafa Mehdipour Ghazi
Objective: Radiomic texture features are usually computed in voxel-index neighborhoods, implicitly assuming isotropic spatial relationships. In anisotropic images, this can confound voxel geometry with interpolation-induced signal changes.
arXiv:2606. 07658v1 Announce Type: cross Abstract: Maximal safe resection is the primary objective in glioma surgery.
By Santiago Cepeda, Olga Esteban-Sinovas, Ignacio Arrese, Rosario Sarabia
The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.
By Valentin Boussot, Cedric Hemon, Caroline Lafond, Jean-Claude Nunes, Jean-Louis Dillenseger
arXiv:2609.13838v1 Announce Type: new
Abstract: Purpose: To develop and evaluate TotalSynth, a reusable pretrained framework for whole-body synthetic CT (sCT) generation from MRI and cone-beam CT (CB...
By Valentin Boussot, Cedric Hemon, Anais Barateau, Caroline Lafond, Jean-Claude Nunes, Jean-Louis Dillenseger
arXiv:2605.05522v3 Announce Type: replace-cross
Abstract: Although self-supervised pretraining is expected to learn broadly transferable representations, its effectiveness across imaging modalities s...
By Aneesh Rangnekar, Joao Miranda, Natally Horvat, Stephanie Chahwan, Samir Alrayess, Aditya Apte, Aditi Iyer, Eve LoCastro, Revathi Ravella, Marc J Gollub, Iva Petkovska, Jesse Joshua Smith, Paul Romesser, Julio Garcia-Aguilar, Harini Veeraraghavan, Joseph O Deasy
CFB-GBM v2.0 is an expanded longitudinal dataset of 264 glioblastoma patients, providing complete Gross Tumour Volume (GTV) delineations across all timepoints and derived volumetric RANO 2.0 response labels. The dataset includes brain masks, pre‑computed radiomic features, and WHO classification guidelines, all validated by radiation oncologists. It is publicly available on TCIA for use in computational methods for treatment response prediction and disease progression modeling.