arXiv AI By Alzahra Altalib, Chunhui Li, Alessandro Perelli

EPC-RawDC: Equivariant Physics Constrained 3D Diffusion with Raw Data Consistency for CBCT to CT Image Synthesis

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EPC‑RawDC is a 3‑D latent diffusion model that synthesises CT images from CBCT scans by enforcing two physics‑based constraints: a geometry‑equivariant projection loss and raw data consistency using scan‑specific CBCT projections. Trained on two clinical cohorts with different scanner geometries, the method achieved SSIM of 0.97 and improved PSNR and MAE over a baseline DDPM, reducing projection and equivariant errors by 55 % and 41 % respectively.

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