arXiv AI

A Negative-Control Protocol for Clinical EEG Foundation-Model Benchmarks: Dataset Identity and External-Cohort Stress Testing

arXiv:2607. 24519v3 Announce Type: replace-cross Abstract: EEG foundation-model gains may depend on cohort, montage, or probe design.

Hugging Face Trending Papers
Jul 27

Stress-Testing EEG Foundation Models for Clinical Decoding: Dataset Identity and Targeted Negative Controls

Pretrained EEG foundation models are increasingly proposed for clinical decoding, but their transfer across populations and robustness to negative controls remain unclear. We benchmark six models (LaBraM, EEGMamba, CBraMod, REVE, BENDR, and BIOT) on five clinical tasks across four datasets using frozen linear probes with leave-one-subject-out, subject-grouped, or explicitly identified recording-level splits.

arXiv AI
3d ago

NeuroAtlas: Benchmarking Foundation Models for Clinical EEG and Brain-Computer Interfaces

NeuroAtlas is the largest EEG benchmark to date, comprising 42 datasets and 260,000 hours of clinical EEG data across epilepsy, sleep medicine, brain age estimation, and brain‑computer interfaces. The study evaluates foundation models (FMs) for EEG against supervised baselines and generic time‑series FMs, finding that EEG‑specific FMs do not consistently outperform generic ones. It also demonstrates that standard machine‑learning metrics are inadequate for clinical relevance, advocating for task‑specific measures such as event‑level decision quality, hypnogram features, and brain‑age gap.

By Konstantinos Kontras, Trui Osselaer, Stylianos G. Mouslech, Angeliki-Ilektra Karaiskou, Guido Gagliardi, Thomas Strypsteen, Mohammad Hossein Badiei, Anku Rani, Maarten Vanmarcke, Miguel Bhagubai, Chanakya Ekbote, Jaedong Hwang, Christos Chatzichristos, Paul Pu Liang, Maarten De Vos
arXiv Machine Learning
Sep 2

Lightweight Adaptation of EEG Foundation Models for Stroke Motor Imagery Decoding: Domain Shift and Subject-Level Robustness

The study investigates whether Low‑Rank Adaptation (LoRA) can adapt three pretrained EEG foundation models—LaBraM‑base, REVE‑base, and REVE‑large—for binary left‑ vs. right‑hand motor imagery decoding in stroke patients. Using subject‑wise five‑fold cross‑validation on the PhysioNet EEG Motor Movement/Imagery Dataset and a binary subset of the UET175 stroke dataset, LoRA significantly improved accuracy for LaBraM‑base (0.822) and REVE‑base (0.957) on the healthy cohort, but only REVE‑base LoRA achieved high performance (0.847±0.194) on stroke data, with a best mean accuracy of 0.952 in leave‑one‑subject‑out evaluation. The results demonstrate that healthy‑benchmark performance does not guarantee transfer to stroke EEG, highlighting the need for target‑domain adaptation and subject‑level assessment in rehabilitation BCIs.

By Anh T. Nguyen, Zihua Sun, Michelle J. Johnson
arXiv AI
Jun 2

CLSP-REQA: A Real-Time Quality-Aware Closed-Loop Seizure Prediction Framework with Mamba-BiLSTM and Confidence-Gated Intervention

arXiv:2606. 00074v1 Announce Type: cross Abstract: Reliable seizure prediction is a prerequisite for closed-loop neurostimulation therapy, yet existing methods rarely account for the variability in EEG signal quality encountered in real-world deployment, and the overwhelming majority adopt non-strict evaluation protocols that overestimate generalisation performance.

By Mufeng Chen, Qi Wu, Bingchao Huang, Xiwen Lai, Zekai Chen, Xinge Ouyang, Quansheng Ren
arXiv Machine Learning
Aug 31

Leveraging a Foundation Model for the EEG-Based Diagnosis of Alzheimer's Disease

The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.

By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung