arXiv Machine Learning

Leakage-Safe Empirical Benchmarking of EEG-Based Machine Learning Pipelines for Dementia Classification

arXiv AI
Oct 1

NeuroAtlas: Benchmarking Foundation Models for Clinical EEG and Brain-Computer Interfaces

NeuroAtlas is the largest EEG benchmark to date, comprising 42 datasets and 260,000 hours of clinical EEG data across epilepsy, sleep medicine, brain age estimation, and brain‑computer interfaces. The study evaluates foundation models (FMs) for EEG against supervised baselines and generic time‑series FMs, finding that EEG‑specific FMs do not consistently outperform generic ones. It also demonstrates that standard machine‑learning metrics are inadequate for clinical relevance, advocating for task‑specific measures such as event‑level decision quality, hypnogram features, and brain‑age gap.

By Konstantinos Kontras, Trui Osselaer, Stylianos G. Mouslech, Angeliki-Ilektra Karaiskou, Guido Gagliardi, Thomas Strypsteen, Mohammad Hossein Badiei, Anku Rani, Maarten Vanmarcke, Miguel Bhagubai, Chanakya Ekbote, Jaedong Hwang, Christos Chatzichristos, Paul Pu Liang, Maarten De Vos
arXiv Machine Learning
Aug 31

Leveraging a Foundation Model for the EEG-Based Diagnosis of Alzheimer's Disease

The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.

By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung
arXiv Machine Learning
Aug 4

SingLEM: Single-Channel Large EEG Model

arXiv:2509. 17920v2 Announce Type: replace Abstract: Current deep learning models for electroencephalography (EEG) are often task-specific and depend on large labeled datasets, limiting their adaptability.

By Jamiyan Sukhbaatar, Satoshi Imamura, Ibuki Inoue, Shoya Murakami, Kazi Mahmudul Hassan, Seungwoo Han, Ingon Chanpornpakdi, Toshihisa Tanaka
arXiv Machine Learning
Oct 16

KnowEEG: Explainable Knowledge Driven EEG Classification

KnowEEG is a feature‑based EEG classification pipeline that extracts 783 per‑electrode statistical features and cross‑brain connectivity metrics, using a balanced sampling strategy to integrate high‑dimensional per‑electrode data with connectivity information. It achieves performance that matches or surpasses state‑of‑the‑art deep learning models on five diverse tasks—including emotion detection, mental workload, eyes open/closed, abnormal EEG, and event detection—without requiring GPU resources. The approach also offers inherent explainability via feature importance rankings, identifying occipital biomarkers in the eyes open/closed task that align with established neuroscience literature.

By Amarpal Sahota, Navid Mohammadi Foumani, Raul Santos-Rodriguez, Zahraa S. Abdallah
Hugging Face Trending Papers
Jul 27

Stress-Testing EEG Foundation Models for Clinical Decoding: Dataset Identity and Targeted Negative Controls

Pretrained EEG foundation models are increasingly proposed for clinical decoding, but their transfer across populations and robustness to negative controls remain unclear. We benchmark six models (LaBraM, EEGMamba, CBraMod, REVE, BENDR, and BIOT) on five clinical tasks across four datasets using frozen linear probes with leave-one-subject-out, subject-grouped, or explicitly identified recording-level splits.

arXiv AI
Sep 28

LEAD: An EEG Foundation Model for Alzheimer's Disease Detection

LEAD is a gated temporal‑spatial Transformer foundation model designed for EEG‑based Alzheimer's disease detection. It was trained on the world’s largest EEG‑AD corpus of 2,238 subjects and uses a subject‑regularized strategy and medical contrastive learning across 13 datasets. LEAD outperforms existing methods on five downstream AD datasets, achieving the best average ranking across 20 evaluations.

By Yihe Wang, Nan Huang, Nadia Mammone, Marco Cecchi, Xiang Zhang
arXiv AI
Sep 15

Schizophrenia Detection from EEG Signals: A Transformer Framework with Spectrogram Representation

The paper presents a transformer-based framework for detecting schizophrenia from EEG signals. It converts preprocessed EEG recordings into spectrograms via Short-Time Fourier Transform and classifies them using both traditional machine learning algorithms and deep learning models, including CNN-Transformer hybrids. Subject-level data partitioning ensures reliable evaluation, yielding an AUC-ROC of 88.41% for the CNN-Transformer model and 92.88% for the CNN + Squeeze and Excitation + Transformer model on an independent test set.

By Abtin Shafiei, Mohsen Hooshmand, Majid Ramezani