arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.
By Simon Baur, Arne Schernich, Ekin B\"oke, Wojciech Samek, Jackie Ma
arXiv:2608.24518v1 Announce Type: new
Abstract: Uncertainty Quantification (UQ) plays a vital role in enhancing the reliability of deep learning model predictions, especially in scenarios with high-d...
By Leonhard F. Feiner, Manuel Nickel, Martin Menten, Laurin Lux, Rickmer Braren, Daniel Rueckert, Georgios Kaissis, Raphael Rehms, Johannes Paetzold
Uncertainty Quantification (UQ) plays a vital role in enhancing the reliability of deep learning model predictions, especially in scenarios with high-dimensional output spaces. This paper addresses th...
arXiv:2606. 18860v1 Announce Type: cross Abstract: Reliable pixel-level uncertainty quantification holds the potential to transform clinical workflows by enabling high-fidelity longitudinal monitoring and distinguishing true pathological changes from artifacts.
By Hana Jebril, Thomas Pinetz, G\"unter Klambauer, Hrvoje Bogunovi\'c
arXiv:2609.39429v1 Announce Type: cross
Abstract: Uncertainty Quantification (UQ) is a key requirement for trustworthy AI in high-stakes medical image analysis. In this work, we evaluate UQ in a mult...
By Gonzalo Esteban Mosquera Rojas, Sebastian R. van der Voort, Carolin M. Pirkl, Sandeep Kaushik, Marion Smits, Stefan Klein
The paper introduces an uncertainty‑driven training framework for 3D CT lung nodule classification that uses validation‑based uncertainty estimates to reweight the loss, aiming to improve predictive performance and probability calibration. Two uncertainty quantification methods—Monte Carlo Dropout and Evidential Deep Learning—are evaluated across multiple backbone architectures (ResNet, DenseNet, EfficientNet, ViT, Swin) on the LIDC‑IDRI and NoduleMNIST3D datasets. The approach yields comparable classification accuracy to conventional training while substantially reducing expected calibration error, especially on convolutional backbones, and shows that simple temperature scaling can also achieve strong calibration.
By Giuseppe Tripodi, Alessandro De Rosis, Saleh Rezaeiravesh
arXiv:2606. 30374v1 Announce Type: cross Abstract: Multimodal MRI is essential for accurate brain tumor segmentation.
By Seunghun Baek, Jihwan Park, Jaeyoon Sim, Hoseok Lee, Seungjoo Lee, Won Hwa Kim
The paper introduces a ground‑truth framework for disentangling uncertainty into epistemic and aleatoric components using sample‑conditional pointwise posterior risk. It evaluates current methods, finding that Spectral‑normalized Neural Gaussian Processes and Variational Latent Gaussian Processes best recover the ground‑truth uncertainty, while most methods align more closely with posterior variance and miss predictor bias. The study also explores the entanglement of estimated uncertainties and the impact of modeling choices, providing practical guidance and releasing 13 semi‑synthetic datasets for further validation.
By Frieder Wizgall, Georg Tirpitz, Moritz Seiler, Kerstin Ritter, B\'alint Mucs\'anyi
arXiv:2603. 04024v2 Announce Type: replace-cross Abstract: Ambiguous 3D medical image segmentation often involves boundaries where different expert delineations are non-identical yet clinically plausible.
By Chao Wu, Mahesh Bhosale, Kangxian Xie, Pouya Karimian, David Doermann, Mingchen Gao
arXiv:2608. 05995v1 Announce Type: new Abstract: Reliable uncertainty estimates are critical in safety-sensitive applications, where understanding the sources of predictive uncertainty is essential.
By Frieder Wizgall, Georg Tirpitz, Moritz Seiler, Kerstin Ritter, B\'alint Mucs\'anyi
arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
By Pranav Kaliaperumal, Manisha Kaliaperumal
arXiv:2607. 28248v1 Announce Type: cross Abstract: The deployment of deep neural networks in safety-critical domains demands reliable estimates of predictive confidence, yet conventional architectures lack principled uncertainty quantification.
By H. Martin Gillis, Thomas Trappenberg