The paper introduces an uncertainty‑driven training framework for 3D CT lung nodule classification that uses validation‑based uncertainty estimates to reweight the loss, aiming to improve predictive performance and probability calibration. Two uncertainty quantification methods—Monte Carlo Dropout and Evidential Deep Learning—are evaluated across multiple backbone architectures (ResNet, DenseNet, EfficientNet, ViT, Swin) on the LIDC‑IDRI and NoduleMNIST3D datasets. The approach yields comparable classification accuracy to conventional training while substantially reducing expected calibration error, especially on convolutional backbones, and shows that simple temperature scaling can also achieve strong calibration.
arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.
arXiv:2606. 06950v1 Announce Type: cross Abstract: Three-dimensional models are widely assumed preferable for volumetric medical imaging, yet their practical value depends on whether performance gains justify added computational cost and complexity.
The paper presents DualTTA, a model‑agnostic framework that improves the calibration of black‑box radiology AI systems by applying clinically grounded test‑time augmentations (geometric and physics‑inspired 3D CT perturbations) and learning probability‑level aggregation strategies. Without accessing model internals or training data, DualTTA achieved the best overall calibration across pulmonary embolism and intracranial hemorrhage detection tasks, reducing Expected Calibration Error by 54% and 43% respectively. It also outperformed traditional uncertainty estimation methods that require internal model access, such as Temperature Scaling, MC Dropout, and Deep Ensembles.
arXiv:2608.21571v1 Announce Type: new Abstract: Lung cancer remains a leading cause of cancer-related mortality worldwide, and early diagnosis is critical for improving survival. However, early-stage...
arXiv:2606. 15479v1 Announce Type: cross Abstract: Steerable convolutional neural networks (Steerable-CNNs) guarantee SE(3)-equivariance by parameterizing kernels as linear combinations of steerable basis functions, but their deterministic nature precludes uncertainty quantification - limiting their use in settings where confidence estimates are essential.
arXiv:2607. 22139v1 Announce Type: cross Abstract: Accurate pixel-level classification of coronary angiograms is critical for cardiovascular disease assessment, yet the field lacks standardized evaluation protocols.
arXiv:2606. 07633v1 Announce Type: cross Abstract: Accurate classification of nuclei subtypes in histopathology images is critical for downstream tasks including tumor grading, immune infiltrate quantification, and prognosis prediction.
arXiv:2609.39429v1 Announce Type: cross Abstract: Uncertainty Quantification (UQ) is a key requirement for trustworthy AI in high-stakes medical image analysis. In this work, we evaluate UQ in a mult...
arXiv:2608.21583v1 Announce Type: new Abstract: Oral cancer is a leading cause of mortality in low-to-middle-income countries, where a shortage of specialists delays diagnosis. While point-of-care sc...
arXiv:2608.28923v1 Announce Type: cross Abstract: Data augmentation is a cornerstone of deep learning pipelines, yet existing strategies treat it as a static, model-agnostic preprocessing step, eithe...
arXiv:2607. 10357v1 Announce Type: cross Abstract: The automatic detection and classification of cardiovascular disease (CVD) from computed tomography (CT) images plays an important role in clinical practice.
arXiv:2606. 09953v1 Announce Type: cross Abstract: Head computed tomography (CT) typically uses sub-millimeter in-plane resolution but 2-5 mm through-plane spacing, creating substantial anisotropy that degrades multiplanar reconstructions, volumetric measurements such as hematoma volume estimation, and downstream algorithms that assume near-isotropic voxels.