The study investigates whether pathology foundation models (PFMs) carry center-related biases into whole-slide image (WSI) classification. By training models with increasing class-center correlations and evaluating six PFMs across four datasets and two MIL aggregators, the authors introduce the Area Under the Cramér's V Curve (AUCC) to measure both accuracy and degradation due to spurious correlations. Results reveal that center information propagates to WSI predictions, with robustness varying by PFM and MIL strategy, and that ComBat harmonization does not consistently improve robustness.
By Il\'an Carretero, Pablo Meseguer, Roc\'io del Amor, Valery Naranjo
Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class skin lesion classification.
arXiv:2606. 18860v1 Announce Type: cross Abstract: Reliable pixel-level uncertainty quantification holds the potential to transform clinical workflows by enabling high-fidelity longitudinal monitoring and distinguishing true pathological changes from artifacts.
By Hana Jebril, Thomas Pinetz, G\"unter Klambauer, Hrvoje Bogunovi\'c
arXiv:2510. 00053v2 Announce Type: replace-cross Abstract: Pathology whole-slide images (WSIs) are widely used for cancer survival analysis because of their comprehensive histopathological information at both cellular and tissue levels, enabling quantitative, large-scale, and prognostically rich tumor feature analysis.
By Yucheng Xing, Ling Huang, Jingying Ma, Ruping Hong, Jiangdong Qiu, Pei Liu, Kai He, Huazhu Fu, Mengling Feng
arXiv:2608. 11280v1 Announce Type: cross Abstract: Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models.
By Rofiqul Islam, Lilatul Ferdouse
arXiv:2609.39429v1 Announce Type: cross
Abstract: Uncertainty Quantification (UQ) is a key requirement for trustworthy AI in high-stakes medical image analysis. In this work, we evaluate UQ in a mult...
By Gonzalo Esteban Mosquera Rojas, Sebastian R. van der Voort, Carolin M. Pirkl, Sandeep Kaushik, Marion Smits, Stefan Klein