arXiv:2607. 22727v1 Announce Type: cross Abstract: Medical image segmentation models often report high benchmark accuracy under ideal imaging conditions, yet their failures under clinical degradation can be quiet: sensor noise, patient motion, low- resolution acquisition, and contrast variability may all alter model behavior without producing an obvious warning.
By Pranav Kaliaperumal, Manisha Kaliaperumal
arXiv:2607. 05035v1 Announce Type: cross Abstract: Few-shot brain tumor segmentation remains challenging due to noisy support masks, inter-patient variations between support and query images, and the lack of pixel-wise confidence estimation.
By Dongyi He, Xiangkai Wang, Binbing Xu, Bin Jiang, Hongjie Yan, Weixiang Liu, Wai Ting Siok, Nizhuan Wang
arXiv:2606. 19300v1 Announce Type: cross Abstract: Glioma segmentation in multiparametric MRI is a critical component of treatment planning.
By Xin Ci Wong, Duygu Sarikaya, Kieran Zucker, Marc De Kamps, Nishant Ravikumar
arXiv:2603. 04024v2 Announce Type: replace-cross Abstract: Ambiguous 3D medical image segmentation often involves boundaries where different expert delineations are non-identical yet clinically plausible.
By Chao Wu, Mahesh Bhosale, Kangxian Xie, Pouya Karimian, David Doermann, Mingchen Gao
Multimodal based approaches often outperform single modality approaches in downstream tasks as the different modalities provide complementary information, yet acquiring paired clinical data remains a significant challenge in real world scenarios. While cross-modal knowledge distillation addresses this, existing methods often struggle with large modality gaps and the propagation of noise from uncertain source-domain predictions.
arXiv:2604. 15271v3 Announce Type: replace-cross Abstract: Reliable uncertainty estimation is critical for medical image segmentation, where automated contours feed downstream quantification and clinical decision support.
By Tianhao Fu, Austin Wang, Charles Chen, Roby Aldave-Garza, Yucheng Chen
arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.
By Simon Baur, Arne Schernich, Ekin B\"oke, Wojciech Samek, Jackie Ma
arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.
By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
arXiv:2603. 17415v2 Announce Type: replace-cross Abstract: Image registration is an ill-posed dense vision task, where multiple solutions achieve similar loss values, motivating probabilistic inference.
By Ivor J. A. Simpson, Neill D. F. Campbell
arXiv:2606. 16484v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) hold great potential for medicine, as they inherit knowledge from LLM and allow multiple data modalities to be integrated, analysed and interpreted in natural language.
By Zhiyun Song, Che Liu, Tian Xia, Avinash Kori, Wenjia Bai
arXiv:2606. 15837v1 Announce Type: cross Abstract: Deep neural networks (DNNs) frequently fail to generalize to out-of-distribution (OOD) medical images because of variations in scanners and acquisition protocols.
By Jimut B. Pal, Suyash P. Awate
arXiv:2605. 00941v5 Announce Type: replace Abstract: Flow matching provides a highly effective framework for generative modeling, yet estimating the uncertainty of its generated samples remains a fundamental challenge.
By Jiarui Xing, Song Wang, Jian Wang