arXiv Machine Learning

BatchBench: Benchmarking AI Robustness to Batch Effects and Domain Shift in Biomedical Images - A JUMP Cell Painting Leaderboard

BatchBench is a new leaderboard designed to assess AI robustness to batch effects and domain shift in biomedical images. It evaluates performance on unseen experimental batches and data sources using the large JUMP-CP dataset, which is generated via the Cell Painting assay and exhibits pronounced batch effects. The benchmark aims to highlight remaining performance gaps despite recent domain adaptation advances.

arXiv Computer Vision
Aug 25

Can Coding Agents Build Robust Baselines? A Skill-Based Approach for Automating the Medical Imaging Model-Development Pipeline

The paper introduces an agentic AI Scientist workflow that automates the entire baseline development process for medical imaging by combining literature-guided reasoning, automated code generation, and hypothesis-driven experimentation. Evaluated on four public benchmarks covering segmentation, classification, and detection, the pipeline consistently improves validation performance, achieving competitive leaderboard results such as 6th place on both PUMA tracks and 31st on MILK10k. The approach also shows strong domain generalization on MIDOG25 across scanners, tumor types, and species, demonstrating that a skill-based, literature-guided agentic workflow can reduce engineering effort without task-specific redesign.

By Eugenia Moris, Jos\'e Ignacio Orlando
arXiv Machine Learning
Jul 31

Scalable Drift Monitoring in Medical Imaging AI

arXiv:2410. 13174v3 Announce Type: replace-cross Abstract: The integration of artificial intelligence (AI) into medical imaging has advanced clinical diagnostics but poses challenges in managing model drift and ensuring long-term reliability.

By Jameson Merkow, Felix J. Dorfner, Xiyu Yang, Alexander Ersoy, Giridhar Dasegowda, Mannudeep Kalra, Matthew P. Lungren, Christopher P. Bridge, Ivan Tarapov
arXiv Machine Learning
Jul 15

Steering Diffusion Models via Class-Contrastive Influence for Few-Shot Medical Classification

arXiv:2607. 12464v1 Announce Type: cross Abstract: When labeled data are scarce, off-the-shelf diffusion models can augment training sets for few-shot medical image classification, but not all generated samples are equally useful for the downstream task.

By Jeeyung Kim, Erfan Esmaeili, Qiang Qiu
arXiv Machine Learning
Aug 31

EXPOSE: Explainable and Domain-Robust Embeddings from Pathology Vision Foundation Models using Sparse Autoencoders

EXPOSE is a framework that applies Sparse Autoencoders to Vision Foundation Model embeddings in computational pathology, aiming to separate biological signals from domain‑specific noise. By training a sparse representation of VFM features and using a linear classifier to flag domain‑specific latent dimensions, the method masks these components before downstream relapse prediction, avoiding the need to retrain the backbone model. Experiments on a large prostate cancer dataset demonstrate that removing domain‑specific features improves cross‑domain performance and raises the Domain Robustness Index (DoRI).

By Anja Witte, Maximilian Lennartz, Jan Baumbach, Guido Sauter, Stefan Bonn, Patrick Fuhlert, Marina Zimmermann
arXiv AI
Jul 14

Imaging-101: Benchmarking LLM Coding Agents on Scientific Computational Imaging

arXiv:2607. 10789v1 Announce Type: new Abstract: Computational imaging, which recovers hidden signals from indirect, noisy measurements, underpins quantitative discovery across scientific disciplines, yet building a correct reconstruction pipeline demands deep domain expertise and remains laborious even for domain scientists.

By Siyi Chen, Jiahe Ying, Yixuan Jia, Yuxuan Gu, Enze Ye, Weimin Bai, Zhijun Zeng, Shaochi Ren, Binhong Gao, Yubing Li, Tianhan Zhang, He Sun
arXiv Computer Vision
Sep 22

AdaptiveCDM: Source-Free Few-Shot Domain Adaptation for Cell Detection in Microscopic Images

AdaptiveCDM is a modular framework for source‑free few‑shot domain adaptation in cell detection, enabling a pretrained model to adapt to new imaging domains using only a handful of labeled target images and no source data. It combines Resolution‑Aware Augmentation (RAug) to balance scarce, class‑imbalanced samples while preserving cellular morphology, and Category‑Aware Representation Learning (CARL) to strengthen class‑consistent proposals for better localization and classification. Experiments on M5 and Raabin‑WBC datasets show that AdaptiveCDM achieves competitive or superior mAP scores compared to state‑of‑the‑art methods under their respective supervision settings.

By Nimra Dilawar, Sara Nadeem, Javed Iqbal, Waqas Sultani, Mohsen Ali