arXiv:2607. 09562v1 Announce Type: cross Abstract: Medical Vision-Language Models (VLMs) exhibit strong zero-shot performance, yet their effectiveness still declines on out-of-distribution (OOD) data due to domain shifts and class bias inherited from large-scale pretraining.
The study investigates why machine‑learning models for tuberculosis screening based on cough acoustics fail to generalize across datasets. Classical ML and deep‑learning classifiers achieved moderate performance within their own datasets (ROC‑AUC up to 0.755) but performed poorly on external data, often below 0.6. The authors found that audio features were more influenced by recording device and dataset than by TB status, and that device‑diverse training improved transfer while device mismatch degraded it. A clinical‑variable baseline showed more consistent generalization, suggesting acquisition‑specific variability is a stronger driver of poor generalizability than population shift.
arXiv:2601.17228v2 Announce Type: replace Abstract: Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches e...
arXiv:2607. 17467v1 Announce Type: cross Abstract: Few-shot Test-Time Domain Adaptation (FSTT-DA) seeks to adapt models to novel domains using only a handful of unlabeled target samples.
arXiv:2608.24281v1 Announce Type: new Abstract: Reducing annotation requirements remains a key challenge in developing robust medical object detectors. To address this, Vision-Language (VL) object de...
arXiv:2608.28923v1 Announce Type: cross Abstract: Data augmentation is a cornerstone of deep learning pipelines, yet existing strategies treat it as a static, model-agnostic preprocessing step, eithe...
Deep learning-based computer-aided diagnosis (CAD) systems have shown strong performance in breast cancer diagnosis, particularly for classification tasks in mammography. However, domain shifts across multi-site datasets remain a challenge, especially when models are applied to unseen domains.
arXiv:2608. 00632v1 Announce Type: new Abstract: Modern machine learning pipelines increasingly rely on reusing pretrained and foundation models across downstream tasks.
arXiv:2407.03463v2 Announce Type: replace-cross Abstract: In the realm of self-supervised learning (SSL), conventional wisdom has gravitated towards the utility of massive, general domain datasets fo...
arXiv:2608. 12035v1 Announce Type: cross Abstract: Deploying unsupervised domain adaptation (UDA) in clinical practice requires choosing which algorithm to use and which of its trained models to ship.
The study evaluates self‑supervised learning (SSL) models pretrained on ImageNet‑1k and the Human Protein Atlas (HPA) Field‑of‑View (FOV) for protein localization in microscopy images. DINO‑based Vision Transformer backbones pretrained on either dataset transfer well to the OpenCell dataset, achieving strong performance even without fine‑tuning and improving further when fine‑tuned (0.704 ± 0.027 macro F1 on 17 classes). At the single‑cell level, the HPA‑pretrained model outperforms others in k‑nearest‑neighbor classification across all neighborhood sizes (macro F1 ≥ 0.515).
The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.