arXiv:2601. 08127v2 Announce Type: replace-cross Abstract: Expert-annotated training data remains the critical bottleneck for AI in histopathology, particularly for rare pathologies where even dozens of cases may be unavailable.
By Mohamad Koohi-Moghadam, Mohammad-Ali Nikouei Mahani, Rex K. H. Au-Yeung, Raymond Yu O, Monalyn Marabi, Piyapharom Intarawichian, Fabian Z. X. Lean, Andrew Ferguson, Kyongtae Tyler Bae
arXiv:2608. 03990v1 Announce Type: new Abstract: Synthetic histopathology image generation has emerged as an approach that may address data scarcity in computational pathology, yet current evaluation methodologies may not fully assess synthetic data quality for medical applications.
By Seyed Kahaki, Shijie Li, Weijie Chen, Nicholas Petrick
arXiv:2607. 12464v1 Announce Type: cross Abstract: When labeled data are scarce, off-the-shelf diffusion models can augment training sets for few-shot medical image classification, but not all generated samples are equally useful for the downstream task.
By Jeeyung Kim, Erfan Esmaeili, Qiang Qiu
arXiv:2608.22532v1 Announce Type: new
Abstract: Domain shift across imaging modalities and acquisition sites remains a significant barrier to the clinical deployment of segmentation models. Source-fr...
By Tal Grossman, Noa Cahan, Hayit Greenspan
Deep learning-based computer-aided diagnosis (CAD) systems have shown strong performance in breast cancer diagnosis, particularly for classification tasks in mammography. However, domain shifts across multi-site datasets remain a challenge, especially when models are applied to unseen domains.
The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.
By Gauthier Miralles, Loic Le Folgoc, Vincent Jugnon, Pietro Gori
arXiv:2608. 12035v1 Announce Type: cross Abstract: Deploying unsupervised domain adaptation (UDA) in clinical practice requires choosing which algorithm to use and which of its trained models to ship.
By Yiheng Xiong, Luisa Gall\'ee, Daniel Santak Wolf, Heiko Hillenhagen, Michael G\"otz
arXiv:2607. 03103v1 Announce Type: cross Abstract: Clinical cardiac imaging pipelines currently deploy separate models for each dataset and modality, incurring redundant training costs and precluding knowledge sharing across anatomically related tasks.
By Jiahao Liu, Hang Wei, Shuai Wu
The paper explores large‑scale pretraining to enhance deep learning‑based geometric distortion correction for diffusion‑weighted imaging (DWI). By framing the task as image reconstruction, the authors compare a non‑pretrained baseline with self‑supervised and generative pretrained models, finding that the cWDM model yields the best quantitative and qualitative results. When applied to low‑resource, high‑throughput settings in a low‑ and middle‑income country, the pretrained models faced transferability issues, but aligning images to a common standard space improved predictions, indicating that harmonized preprocessing can aid cross‑domain deployment.
By Saroj Khanal, Yashawant Kumar Yadav, Kritam Bhattarai, Jeevan Neupane, Shristi Subedi, Saship Gwachha, Manish Kumar Tiwari, Dong Zhang, Confidence Raymond, Aondona Moses Iorumbur, Udunna Anazodo, Surendra Maharjan, Bishesh Khanal, Mahesh Shakya, Pralhad Kumar Shrestha
arXiv:2605. 23995v4 Announce Type: replace-cross Abstract: Self-supervised learning (SSL) is increasingly used in medical image analysis to reduce dependence on costly expert annotations by learning transferable representations from unlabeled data.
By Chathura Wimalasiri, Kishor Nandakishor, Marimuthu Palaniswami
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv:2511.05782v3 Announce Type: replace
Abstract: Unsupervised domain adaptation (UDA) for medical image segmentation remains challenging due to substantial domain shifts across imaging modalities,...
By Lalit Maurya, Honghai Liu, Reyer Zwiggelaar