arXiv Computer Vision

AdaptiveCDM: Source-Free Few-Shot Domain Adaptation for Cell Detection in Microscopic Images

AdaptiveCDM is a modular framework for source‑free few‑shot domain adaptation in cell detection, enabling a pretrained model to adapt to new imaging domains using only a handful of labeled target images and no source data. It combines Resolution‑Aware Augmentation (RAug) to balance scarce, class‑imbalanced samples while preserving cellular morphology, and Category‑Aware Representation Learning (CARL) to strengthen class‑consistent proposals for better localization and classification. Experiments on M5 and Raabin‑WBC datasets show that AdaptiveCDM achieves competitive or superior mAP scores compared to state‑of‑the‑art methods under their respective supervision settings.

arXiv Machine Learning
Aug 12

Retrieval-Augmented Vision Foundation Models for Robust Leukemia Cell Classification across Multiple Microscopy Datasets

arXiv:2608. 10657v1 Announce Type: cross Abstract: Leukemia cell image classification is challenged by real-world domain shifts from acquisition, staining, illumination, and site protocols, causing single-dataset models to generalize poorly in real clinical scenarios.

By Carlos Zamora, Hiram Zuniga, Ulises Orozco-Rosas, Kenia Picos
arXiv AI
Sep 25

A Multimodal 3D Foundation Model for Light Sheet Fluorescence Microscopy Enables Few-Shot Segmentation, Classification, and Deblurring

The paper presents a 3D foundation model for light sheet fluorescence microscopy (LSM) that is pretrained on a large curated set of 3D images from various organisms, stains, and imaging protocols. By jointly optimizing for masked reconstruction and image‑text alignment, the model learns transferable volumetric representations that dramatically reduce the need for annotated data. The pretrained backbone enables efficient few‑shot adaptation to downstream tasks such as segmentation, classification, and deblurring, consistently outperforming baselines according to standard metrics and expert evaluation.

By Adina Scheinfeld, Haotan Zhang, Shang Mu, Rudolf L. M. van Herten, Lucas Stoffl, Ali Erturk, Zhuhao Wu, Johannes C. Paetzold
arXiv Computer Vision
Aug 26

Example-based Robust Abnormality Detection with Minimal Annotations using Exemplar Med-DETR

arXiv:2608.24281v1 Announce Type: new Abstract: Reducing annotation requirements remains a key challenge in developing robust medical object detectors. To address this, Vision-Language (VL) object de...

By Sheethal Bhat, Bogdan Georgescu, Awais Mansoor, Mathias Zinnen, Pranjal Sahu, Florin C. Ghesu, Sasa Grbic, Andreas Maier
arXiv Machine Learning
Aug 18

Comprehensive language-image pre-training for 3D medical image understanding

arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.

By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia