arXiv:2607. 07189v1 Announce Type: new Abstract: Vision-language models (VLMs) and agentic AI have shown strong performance on semantic visual tasks, but it remains unclear whether they can handle the physics and inverse problems that underlie computational imaging.
By Ethan Chung, Chuanjun Zheng, Jasper Tan, Jingxi Li, Haopeng Zhang, Huaijin Chen
The paper introduces an agentic AI Scientist workflow that automates the entire baseline development process for medical imaging by combining literature-guided reasoning, automated code generation, and hypothesis-driven experimentation. Evaluated on four public benchmarks covering segmentation, classification, and detection, the pipeline consistently improves validation performance, achieving competitive leaderboard results such as 6th place on both PUMA tracks and 31st on MILK10k. The approach also shows strong domain generalization on MIDOG25 across scanners, tumor types, and species, demonstrating that a skill-based, literature-guided agentic workflow can reduce engineering effort without task-specific redesign.
By Eugenia Moris, Jos\'e Ignacio Orlando
arXiv:2607. 10522v1 Announce Type: cross Abstract: Large language model (LLM) agents are beginning to automate machine learning engineering (MLE) by coupling planning, code execution, debugging, and empirical feedback.
By Shengyuan Liu, Jia-Xuan Jiang, Boyun Zheng, Cheng Wang, Zipei Wang, Wentao Pan, Hongtao Wu, Houwen Peng, Yu Gu, Lichao Sun, Yixuan Yuan
Large language model (LLM) agents are beginning to automate machine learning engineering (MLE) by coupling planning, code execution, debugging, and empirical feedback. Translating this capability to medical imaging remains difficult because each task imposes modality-specific experimentation and strict requirements for validation protocols and prediction artifacts.
arXiv:2605. 11359v3 Announce Type: replace Abstract: Scientific data processing often requires task-specific algorithms or AI models, creating a barrier for domain scientists who need to analyze their data but may not have extensive computing or image-processing expertise.
By Ming Du, Xiangyu Yin, Yanqi Luo, Dishant Beniwal, Songyuan Tang, Hemant Sharma, Mathew J. Cherukara
arXiv:2606. 00472v1 Announce Type: cross Abstract: Conventional tissue image analysis software provides foundational capabilities for cellular analysis, including segmentation, basic morphological feature extraction, and spatial organization analysis.
By Hung Q. Vo, Huy Q. Vo, Son T. Ly, Zhihao Wan, Anh-Vu Nguyen, Hong Zhao, Jianting Sheng, Stephen T. C. Wong, Hien V. Nguyen
arXiv:2508. 05321v4 Announce Type: replace-cross Abstract: Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available.
By Laura Hellwege, Johann Christopher Engster, Moritz Schaar, Thorsten M. Buzug, Maik Stille
The paper critiques the prevailing model-first approach in AI-driven image processing, arguing that researchers often prioritize benchmark performance over genuine understanding of real-world imaging problems. It proposes a problem-first framework that separates the physical imaging issue, solution principle, statistical estimator, and computational implementation, and introduces a six-stage workflow to guide research from problem formulation to evaluation. Case studies in super-resolution and low-light enhancement illustrate how benchmark datasets can misrepresent real tasks and emphasize the need for clearer standards on evidence, reproducibility, and uncertainty.
By Guoping Qiu
nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.
By Constantin Ulrich Harsy, Tassilo Wald, Karol Gotkowski, Yannick Kirchhoff, Marcel Knopp, Maximilian Rokuss, Elisa Stegmeier, Philipp Schader, Dasha Trofimova, Raphael Stock, Kim-Celine Kahl, Stephen Schaumann, Selen Erkan, David Zimmerer, Stefan Denner, Moritz Langenberg, Sebastian Ziegler, Katharina Eckstein, Maximilian Fischer, Jonathan Suprijadi, B\'alint Kov\'acs, Benjamin Hamm, Anand Deshpande, Dimitrios Bounias, Nico Disch, Shuhan Xiao, Jessica K\"achele, Jan Sellner, Rajesh Baidya, Jeremias Traub, Lars Kr\"amer, Maximilian Zenk, Tim R\"adsch, Stefan Dvoretskii, Robin Peretzke, Jonathan Deissler, Alexandra Ertl, Partha Ghosh, Kris Dreher, Stefan Dinkelacker, Annika Reinke, Evangelia Christodoulou, Numan Saeed, Yoland Savriama, Santiago Estrada, David K\"ugler, Laura Alexandra Daza Barragan, Cristina Isabel Gonzalez Osorio, Jan Peeken, Michael Baumgartner, Marvin Teichmann, Guillaume Chabin, Matthias Kirchler, Valentin Koch, for the ALFA study, Markus Hohenhaus, Dimitri Koslov, Nina Decker, Mohammad Yaqub, Arnd Heuser, Martin Reuter, Julia A. Schnabel, Tobias Heimann, Florin Ghesu, Paul Brachmann, Claus P. Heu{\ss}el, Alexander Radbruch, Gianluca Brugnara, Aditya Rastogi, Martha Foltyn-Dumitru, Heinz-Peter Schlemmer, Ignaz Reicht, Julius C. Holzschuh, Michael Bach, Bram Stieltjes, Kai Schlamp, Lena Maier-Hein, Marco Nolden, Ralf Floca, Paul F. J\"ager, Philipp Vollmuth, Fabian Isensee, Klaus H. Maier-Hein
arXiv:2604.16729v2 Announce Type: replace-cross
Abstract: State-of-the-art large language models (LLMs) show high performance in general visual question answering. However, a fundamental limitation r...
By Ayhan Can Erdur, Daniel Scholz, Jiazhen Pan, Benedikt Wiestler, Daniel Rueckert, Jan C. Peeken
arXiv:2608. 05839v1 Announce Type: cross Abstract: Deep neural networks have shown great empirical success in the solution of a wide variety of ill-posed inverse problems in imaging.
By Alexander Auras, Martin Burger, Samira Kabri, Michael Moeller, Michael Schopf-Kuester
arXiv:2606. 07718v1 Announce Type: new Abstract: Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where scientists care about correctness and robustness, not implementation details.
By Kai A. Horstmann, Ethan Lin, Alice A. Robie, Jennifer J. Sun, Kristin Branson