arXiv Machine Learning

Mitigating Class-Tail Undercoverage in Medical Vision-Language Models under Clinical Shift

arXiv:2607. 28696v1 Announce Type: new Abstract: Medical vision-language models (VLMs) can retain high observed marginal coverage after clinical shift while substantially under-covering an individual disease class.

arXiv Machine Learning
Jul 9

A Quiet Failure in Calibrated Virtual Screening: Marginal Conformal Prediction Under-Covers the Minority Class, and a Class-Conditional Fix Recovers It

arXiv:2607. 06605v1 Announce Type: new Abstract: Conformal prediction is being adopted in drug discovery to put an honest number on model reliability: pick an error rate alpha, and the method returns prediction sets containing the true label with probability at least 1 - alpha.

By Muhammadjon Tursunbadalov (School of Science and Technology, Champions College Prep, United States), Mustafojon Tursunbadalov (School of Science and Technology, Champions College Prep, United States)
arXiv Machine Learning
5d ago

Missingness-Aware Conformal Prediction Under Cross-Hospital Distribution Shift

The paper introduces a missingness‑aware conformal calibration method for mortality prediction that accounts for cross‑hospital distribution shifts. By selecting a measurement on an independent sample, grouping patients by whether that measurement is recorded, and applying Mondrian calibration within each group, the method avoids reusing calibration outcomes. Experiments on eICU and MIMIC‑IV data show that, compared to pooled calibration, it reduces the worst‑group coverage gap by a median of 1.9 percentage points across six settings, though the benefit varies with predictor and hospital.

By Liang You, Dongwen Ou, Hengyu Shi, Siyuan Dai
arXiv AI
Sep 15

Adaptive Conformal Redistribution for Inter-class Transitional Uncertainty in Medical Image Classification

The paper introduces AdaConRed, a label‑free post‑conformal decision rule that transforms ambiguous conformal prediction sets into single class assignments for medical image classification. It employs a five‑stage pipeline—vision‑language generative augmentation, a frozen DermFoundation encoder, a lightweight MLP classifier, an entropy‑modulated margin‑aware nonconformity score, and a reassignment step for transitional samples—to improve accuracy on OSCC and ISIC benchmarks. Results show notable gains in malignant class accuracy while maintaining overall performance.

By Saibal Ghosh, Samarup Bhattacharya, Sanjoy Kumar Saha, Umapada Pal, Tapabrata Chakraborti
arXiv Machine Learning
Jul 30

CalTwin: Towards Calibrated, Shift-Robust Medical World Models via Fisher-Information Regularisation

arXiv:2607. 26752v1 Announce Type: new Abstract: Medical world models aim to learn a latent state of patient or organ physiology and a transition function that forecasts how that state evolves under interventions, supporting downstream tasks from imaging-based diagnosis to digital-twin treatment planning.

By Behraj Khan, Shabir Ahmad, Syed Ahmad Chan Bukhari, Tahir Qasim Syed
arXiv Computer Vision
Aug 28

MVC-Bench: Benchmarking Calibration of Medical Vision-Language Models

MVC-Bench is a new benchmark designed to evaluate the calibration of vision‑language models (VLMs) and medical VLMs (Medical‑VLMs) for medical image classification. It tests calibration across robustness to modality, backbone, and domain shift; effectiveness of calibration strategies and prompt‑tuning methods; and stability under prompt‑template and random‑seed variations. The benchmark includes eight backbones, three medical modalities (fundus imaging, histopathology, chest X‑ray), and compares post‑hoc, train‑time, and zero‑shot calibration approaches, reporting accuracy, Expected Calibration Error (ECE), Maximum Calibration Error (MCE), and Adaptive Calibration Error (ACE) over 1,638 experiments, while also proposing a Multi‑Class Margin (MCM) regularization technique that improves ECE in most settings.

By Ashshak Sharifdeen, Shihab Aaqil Ahamed, Ufaq Khan, Muhammad Akhtar Munir Sujair Ibrahim, Mohamed Rafeek Mareer Ahamed, Yutong Xie, Imran Razzak, Muhammad Haris Khan
Hugging Face Trending Papers
Aug 27

MVC-Bench: Benchmarking Calibration of Medical Vision-Language Models

MVC-Bench is a calibration-focused benchmark for medical vision‑language models, evaluating how well these models express confidence across different modalities, backbones, and domain shifts. It tests robustness to modality, backbone, and domain changes, the effectiveness of calibration and prompt‑tuning strategies, and stability under prompt‑template and random‑seed variations. The benchmark includes 1638 experiments, reporting accuracy and Expected Calibration Error (ECE) along with other calibration metrics, and introduces a simple train‑time calibration method, Multi‑Class Margin (MCM) regularization, that achieves the lowest ECE in most settings.