arXiv Machine Learning

A Multi-Cohort Validation of Censoring-Aware Conformal Lower Predictive Bounds for Pathology Survival Models

arXiv:2608. 04025v1 Announce Type: cross Abstract: Whole-slide survival models commonly provide risk rankings without calibrated statements about individual event times.

arXiv Machine Learning
Jul 22

When Are Scoring Rules Proper? Bridging Theory and Practice in Survival Model Evaluation

arXiv:2212. 05260v4 Announce Type: replace-cross Abstract: Proper scoring rules encourage probabilistic predictions that match the true underlying distribution and are central to model evaluation, with increasing relevance in automated workflows such as AutoML.

By John Zobolas, Raphael Sonabend, Riccardo De Bin, Johannes Piller, Philipp Kopper, Lukas Burk, Andreas Bender
arXiv Machine Learning
Sep 18

Machine-Learning Assessment of the Predictive Value of Inflammatory Biomarkers for Cognitive Impairment in an Older Hispanic Adult Cohort

The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.

By Antony Garcia, Gabrielle Britton, Alcibiades Villarreal, Diana Oviedo, Giselle Rangel, Xinming Huang
arXiv Machine Learning
Jul 24

Multimodality Stacking with Blockwise missing values and application to the PIONeeR biomarkers study for prediction of resistance to immunotherapy

arXiv:2605. 25050v2 Announce Type: replace-cross Abstract: Integrating multimodal datasets in clinical oncology is frequently hindered by high dimensionality and blockwise missingness, where entire data sources are unavailable for specific patient subsets.

By Mohamed Boussena, Florence Monville, Jacques Fieschi-Meric, Frederic Vely, Pierre Milpied, Julien Mazieres, Maurice Perol, Eric Vivier, Laurent Greillier, Fabrice Barlesi, Sebastien Benzekry
arXiv Computation and Language
3d ago

Large Language Models are Approximate Survival Estimators

arXiv:2609.38181v1 Announce Type: new Abstract: Survival analysis estimates time-to-event outcomes from patient covariates and is widely used for medical risk assessment. Patients seeking prognostic...

By Juan M Zambrano Chaves, Peniel Argaw, Risa Ueno, Carlo Bifulco, Kristina Young, Rom Leidner, Tristan Naumann, Hoifung Poon
arXiv Machine Learning
Sep 14

In-Hospital Stroke Risk-State Classification from PPG-Derived Hemodynamic Features

The study develops a 1‑D ResNet classifier that uses a fixed 17‑channel hemodynamic representation derived from photoplethysmography (PPG) to predict in‑hospital stroke risk states up to six hours before clinical recognition. Using data from MIMIC‑III and MC‑MED, the model achieved F1‑scores ranging from 0.7956 to 0.9888 across 4‑, 5‑, and 6‑hour horizons, outperforming four non‑waveform clinical and structured‑EHR comparators in all cohort‑horizon settings. Retrospective analysis showed that the PPG model’s false‑positive rates on high‑risk non‑stroke controls could be reduced through persistence aggregation, though the study does not establish a calibrated bedside alarm or a clinically validated prediction lead time.

By Jiaming Liu, Cheng Ding, Jian Wu, Hongxia Xu, Daoqiang Zhang