arXiv:2606. 08305v1 Announce Type: cross Abstract: Externally controlled survival trials are increasingly used when concurrent randomized controls are infeasible, particularly in oncology and rare-disease settings with time-to-event endpoints.
By Se Yoon Lee, Yonghyun Kwon, Jae Kwang Kim
arXiv:2212. 05260v4 Announce Type: replace-cross Abstract: Proper scoring rules encourage probabilistic predictions that match the true underlying distribution and are central to model evaluation, with increasing relevance in automated workflows such as AutoML.
By John Zobolas, Raphael Sonabend, Riccardo De Bin, Johannes Piller, Philipp Kopper, Lukas Burk, Andreas Bender
arXiv:2607. 28696v1 Announce Type: new Abstract: Medical vision-language models (VLMs) can retain high observed marginal coverage after clinical shift while substantially under-covering an individual disease class.
By Mushir Akhtar, M. Tanveer
arXiv:2606. 06393v1 Announce Type: new Abstract: Proper scoring rules provide a rigorous theoretical basis for the training and evaluation of probabilistic forecasts.
By Jef Jonkers, Glenn Van Wallendael, Luc Duchateau, Sofie Van Hoecke
arXiv:2606. 18281v1 Announce Type: cross Abstract: Conditional average treatment effects (CATEs) are central to treatment decision-making in personalized medicine.
By Daniel Klippert, Sarah Friedrich, Markus Pauly
arXiv:2608. 16594v1 Announce Type: new Abstract: Cancer survival prediction supports treatment planning, risk stratification, and follow-up management.
By Tianqi Xiang, Qixiang Zhang, Xinpeng Ding, Yi Li, Xiaomeng Li
The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.
By Antony Garcia, Gabrielle Britton, Alcibiades Villarreal, Diana Oviedo, Giselle Rangel, Xinming Huang
arXiv:2605. 25050v2 Announce Type: replace-cross Abstract: Integrating multimodal datasets in clinical oncology is frequently hindered by high dimensionality and blockwise missingness, where entire data sources are unavailable for specific patient subsets.
By Mohamed Boussena, Florence Monville, Jacques Fieschi-Meric, Frederic Vely, Pierre Milpied, Julien Mazieres, Maurice Perol, Eric Vivier, Laurent Greillier, Fabrice Barlesi, Sebastien Benzekry
arXiv:2607. 25497v1 Announce Type: cross Abstract: Pathology foundation models are approaching clinical deployment, yet remain vulnerable to systematic non-biological variation across centres.
By Cl\'ement Grisi, Jeroen van der Laak, Geert Litjens
arXiv:2607. 16802v1 Announce Type: new Abstract: Deep survival models are evaluated almost exclusively by the concordance index (C-index), yet they are commonly trained using likelihood objectives such as the Cox partial likelihood, discrete-time negative log-likelihood, and DeepHit likelihood.
By Meixu Chen, Kai Wang, Jing Wang
arXiv:2609.38181v1 Announce Type: new
Abstract: Survival analysis estimates time-to-event outcomes from patient covariates and is widely used for medical risk assessment. Patients seeking prognostic...
By Juan M Zambrano Chaves, Peniel Argaw, Risa Ueno, Carlo Bifulco, Kristina Young, Rom Leidner, Tristan Naumann, Hoifung Poon
The study develops a 1‑D ResNet classifier that uses a fixed 17‑channel hemodynamic representation derived from photoplethysmography (PPG) to predict in‑hospital stroke risk states up to six hours before clinical recognition. Using data from MIMIC‑III and MC‑MED, the model achieved F1‑scores ranging from 0.7956 to 0.9888 across 4‑, 5‑, and 6‑hour horizons, outperforming four non‑waveform clinical and structured‑EHR comparators in all cohort‑horizon settings. Retrospective analysis showed that the PPG model’s false‑positive rates on high‑risk non‑stroke controls could be reduced through persistence aggregation, though the study does not establish a calibrated bedside alarm or a clinically validated prediction lead time.
By Jiaming Liu, Cheng Ding, Jian Wu, Hongxia Xu, Daoqiang Zhang