arXiv Machine Learning By Liang You, Dongwen Ou, Hengyu Shi, Siyuan Dai

Missingness-Aware Conformal Prediction Under Cross-Hospital Distribution Shift

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The paper introduces a missingness‑aware conformal calibration method for mortality prediction that accounts for cross‑hospital distribution shifts. By selecting a measurement on an independent sample, grouping patients by whether that measurement is recorded, and applying Mondrian calibration within each group, the method avoids reusing calibration outcomes. Experiments on eICU and MIMIC‑IV data show that, compared to pooled calibration, it reduces the worst‑group coverage gap by a median of 1.9 percentage points across six settings, though the benefit varies with predictor and hospital.

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